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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GFPT1
Full Name:
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
Alias:
D-fructose-6-phosphate amidotransferase 1; Glutamine:fructose 6 phosphate amidotransferase 1; Glutamine;fructose 6 phosphate amidotransferase 1; Hexosephosphate aminotransferase 1
Type:
Transferase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.6.1.16
Mass (Da):
78806
Number AA:
699
UniProt ID:
Q06210
International Prot ID:
IPI00217952
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004360
GO:0005529
PhosphoSite+
KinaseNET
Biological Process:
GO:0016051
GO:0006112
GO:0006002
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
G
I
F
A
Y
L
N
Y
H
V
P
R
T
R
R
Site 2
T15
L
N
Y
H
V
P
R
T
R
R
E
I
L
E
T
Site 3
T22
T
R
R
E
I
L
E
T
L
I
K
G
L
Q
R
Site 4
Y32
K
G
L
Q
R
L
E
Y
R
G
Y
D
S
A
G
Site 5
Y35
Q
R
L
E
Y
R
G
Y
D
S
A
G
V
G
F
Site 6
S37
L
E
Y
R
G
Y
D
S
A
G
V
G
F
D
G
Site 7
T98
I
A
H
T
R
W
A
T
H
G
E
P
S
P
V
Site 8
S103
W
A
T
H
G
E
P
S
P
V
N
S
H
P
Q
Site 9
S107
G
E
P
S
P
V
N
S
H
P
Q
R
S
D
K
Site 10
Y141
K
F
L
E
S
K
G
Y
D
F
E
S
E
T
D
Site 11
S145
S
K
G
Y
D
F
E
S
E
T
D
T
E
T
I
Site 12
T149
D
F
E
S
E
T
D
T
E
T
I
A
K
L
V
Site 13
T151
E
S
E
T
D
T
E
T
I
A
K
L
V
K
Y
Site 14
Y158
T
I
A
K
L
V
K
Y
M
Y
D
N
R
E
S
Site 15
Y160
A
K
L
V
K
Y
M
Y
D
N
R
E
S
Q
D
Site 16
S165
Y
M
Y
D
N
R
E
S
Q
D
T
S
F
T
T
Site 17
T168
D
N
R
E
S
Q
D
T
S
F
T
T
L
V
E
Site 18
S169
N
R
E
S
Q
D
T
S
F
T
T
L
V
E
R
Site 19
T201
F
P
G
Q
A
V
G
T
R
R
G
S
P
L
L
Site 20
S205
A
V
G
T
R
R
G
S
P
L
L
I
G
V
R
Site 21
S213
P
L
L
I
G
V
R
S
E
H
K
L
S
T
D
Site 22
S218
V
R
S
E
H
K
L
S
T
D
H
I
P
I
L
Site 23
Y226
T
D
H
I
P
I
L
Y
R
T
A
R
T
Q
I
Site 24
T228
H
I
P
I
L
Y
R
T
A
R
T
Q
I
G
S
Site 25
S235
T
A
R
T
Q
I
G
S
K
F
T
R
W
G
S
Site 26
S242
S
K
F
T
R
W
G
S
Q
G
E
R
G
K
D
Site 27
S253
R
G
K
D
K
K
G
S
C
N
L
S
R
V
D
Site 28
S257
K
K
G
S
C
N
L
S
R
V
D
S
T
T
C
Site 29
S261
C
N
L
S
R
V
D
S
T
T
C
L
F
P
V
Site 30
T262
N
L
S
R
V
D
S
T
T
C
L
F
P
V
E
Site 31
T263
L
S
R
V
D
S
T
T
C
L
F
P
V
E
E
Site 32
Y276
E
E
K
A
V
E
Y
Y
F
A
S
D
A
S
A
Site 33
S308
A
V
V
D
G
R
L
S
I
H
R
I
K
R
T
Site 34
T315
S
I
H
R
I
K
R
T
A
G
D
H
P
G
R
Site 35
S353
E
I
F
E
Q
P
E
S
V
V
N
T
M
R
G
Site 36
T357
Q
P
E
S
V
V
N
T
M
R
G
R
V
N
F
Site 37
Y367
G
R
V
N
F
D
D
Y
T
V
N
L
G
G
L
Site 38
T368
R
V
N
F
D
D
Y
T
V
N
L
G
G
L
K
Site 39
T394
L
I
L
I
A
C
G
T
S
Y
H
A
G
V
A
Site 40
T427
S
D
F
L
D
R
N
T
P
V
F
R
D
D
V
Site 41
S439
D
D
V
C
F
F
L
S
Q
S
G
E
T
A
D
Site 42
T447
Q
S
G
E
T
A
D
T
L
M
G
L
R
Y
C
Site 43
Y453
D
T
L
M
G
L
R
Y
C
K
E
R
G
A
L
Site 44
T467
L
T
V
G
I
T
N
T
V
G
S
S
I
S
R
Site 45
S470
G
I
T
N
T
V
G
S
S
I
S
R
E
T
D
Site 46
S471
I
T
N
T
V
G
S
S
I
S
R
E
T
D
C
Site 47
S473
N
T
V
G
S
S
I
S
R
E
T
D
C
G
V
Site 48
T476
G
S
S
I
S
R
E
T
D
C
G
V
H
I
N
Site 49
Y553
Q
K
L
A
T
E
L
Y
H
Q
K
S
V
L
I
Site 50
S557
T
E
L
Y
H
Q
K
S
V
L
I
M
G
R
G
Site 51
Y617
I
I
M
R
D
H
T
Y
A
K
C
Q
N
A
L
Site 52
T645
C
D
K
E
D
T
E
T
I
K
N
T
K
R
T
Site 53
Y684
H
L
A
V
L
R
G
Y
D
V
D
F
P
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation