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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Bcl-xL
Full Name:
Bcl-2-like protein 1
Alias:
Apoptosis regulator Bcl-X; BCL2L; BCL2L1; BCL2-like 1; Bcl-2-like 1 protein; BCLX; Bcl-X; BCLXL; Bcl-xS; BLC2L
Type:
Apoptosis protein, Bcl family
Mass (Da):
26049
Number AA:
233
UniProt ID:
Q07817
International Prot ID:
IPI00019983
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005741
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0008634
GO:0046902
GO:0051881
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
L
V
V
D
F
L
S
Y
K
L
S
Q
K
G
Site 2
S18
D
F
L
S
Y
K
L
S
Q
K
G
Y
S
W
S
Site 3
Y22
Y
K
L
S
Q
K
G
Y
S
W
S
Q
F
S
D
Site 4
S23
K
L
S
Q
K
G
Y
S
W
S
Q
F
S
D
V
Site 5
S25
S
Q
K
G
Y
S
W
S
Q
F
S
D
V
E
E
Site 6
S28
G
Y
S
W
S
Q
F
S
D
V
E
E
N
R
T
Site 7
T35
S
D
V
E
E
N
R
T
E
A
P
E
G
T
E
Site 8
S43
E
A
P
E
G
T
E
S
E
M
E
T
P
S
A
Site 9
T47
G
T
E
S
E
M
E
T
P
S
A
I
N
G
N
Site 10
S49
E
S
E
M
E
T
P
S
A
I
N
G
N
P
S
Site 11
S56
S
A
I
N
G
N
P
S
W
H
L
A
D
S
P
Site 12
S62
P
S
W
H
L
A
D
S
P
A
V
N
G
A
T
Site 13
T69
S
P
A
V
N
G
A
T
G
H
S
S
S
L
D
Site 14
S74
G
A
T
G
H
S
S
S
L
D
A
R
E
V
I
Site 15
Y101
G
D
E
F
E
L
R
Y
R
R
A
F
S
D
L
Site 16
S106
L
R
Y
R
R
A
F
S
D
L
T
S
Q
L
H
Site 17
T109
R
R
A
F
S
D
L
T
S
Q
L
H
I
T
P
Site 18
S110
R
A
F
S
D
L
T
S
Q
L
H
I
T
P
G
Site 19
T115
L
T
S
Q
L
H
I
T
P
G
T
A
Y
Q
S
Site 20
T118
Q
L
H
I
T
P
G
T
A
Y
Q
S
F
E
Q
Site 21
Y120
H
I
T
P
G
T
A
Y
Q
S
F
E
Q
V
V
Site 22
S122
T
P
G
T
A
Y
Q
S
F
E
Q
V
V
N
E
Site 23
T190
Q
E
N
G
G
W
D
T
F
V
E
L
Y
G
N
Site 24
S228
A
G
V
V
L
L
G
S
L
F
S
R
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation