PhosphoNET

           
Protein Info 
   
Short Name:  SF2
Full Name:  Serine/arginine-rich splicing factor 1
Alias:  Alternate splicing factor; Alternative splicing factor ASF-1; ASF; ASF-1; MGC5228; Pre-mRNA splicing factor SF2, P33 subunit; Pre-mRNA-splicing factor SF2; Pre-mRNA-splicing factor SF2, P33 subunit; SF2P33; SFRS1; Splicing factor 2; Splicing factor, arginine/serine-rich 1; SRp30a
Type:  RNA binding protein
Mass (Da):  27745
Number AA:  247
UniProt ID:  Q07955
International Prot ID:  IPI00215884
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0016607  GO:0005681 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006376     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSGGGVIRG
Site 2Y19GNNDCRIYVGNLPPD
Site 3Y37KDIEDVFYKYGAIRD
Site 4Y39IEDVFYKYGAIRDID
Site 5Y72RDAEDAVYGRDGYDY
Site 6Y77AVYGRDGYDYDGYRL
Site 7Y79YGRDGYDYDGYRLRV
Site 8Y82DGYDYDGYRLRVEFP
Site 9S91LRVEFPRSGRGTGRG
Site 10T95FPRSGRGTGRGGGGG
Site 11Y112GGAPRGRYGPPSRRS
Site 12S116RGRYGPPSRRSENRV
Site 13S119YGPPSRRSENRVVVS
Site 14S131VVSGLPPSGSWQDLK
Site 15S133SGLPPSGSWQDLKDH
Site 16Y149REAGDVCYADVYRDG
Site 17Y153DVCYADVYRDGTGVV
Site 18T157ADVYRDGTGVVEFVR
Site 19T169FVRKEDMTYAVRKLD
Site 20Y170VRKEDMTYAVRKLDN
Site 21T178AVRKLDNTKFRSHEG
Site 22S182LDNTKFRSHEGETAY
Site 23T187FRSHEGETAYIRVKV
Site 24Y189SHEGETAYIRVKVDG
Site 25S199VKVDGPRSPSYGRSR
Site 26S201VDGPRSPSYGRSRSR
Site 27Y202DGPRSPSYGRSRSRS
Site 28S205RSPSYGRSRSRSRSR
Site 29S207PSYGRSRSRSRSRSR
Site 30S209YGRSRSRSRSRSRSR
Site 31S211RSRSRSRSRSRSRSR
Site 32S213RSRSRSRSRSRSRSN
Site 33S215RSRSRSRSRSRSNSR
Site 34S217RSRSRSRSRSNSRSR
Site 35S219RSRSRSRSNSRSRSY
Site 36S221RSRSRSNSRSRSYSP
Site 37S223RSRSNSRSRSYSPRR
Site 38S225RSNSRSRSYSPRRSR
Site 39Y226SNSRSRSYSPRRSRG
Site 40S227NSRSRSYSPRRSRGS
Site 41S231RSYSPRRSRGSPRYS
Site 42S234SPRRSRGSPRYSPRH
Site 43Y237RSRGSPRYSPRHSRS
Site 44S238SRGSPRYSPRHSRSR
Site 45S242PRYSPRHSRSRSRT_
Site 46S244YSPRHSRSRSRT___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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