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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cdc16
Full Name:
Cell division cycle protein 16 homolog
Alias:
CDC16Hs
Type:
Mass (Da):
71656
Number AA:
620
UniProt ID:
Q13042
International Prot ID:
IPI00022091
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005680
GO:0005813
GO:0005829
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051301
GO:0008283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
L
R
K
R
V
R
Q
Y
L
D
Q
Q
Q
Y
Q
Site 2
Y19
Q
Y
L
D
Q
Q
Q
Y
Q
S
A
L
F
W
A
Site 3
S31
F
W
A
D
K
V
A
S
L
S
R
E
E
P
Q
Site 4
S33
A
D
K
V
A
S
L
S
R
E
E
P
Q
D
I
Site 5
Y41
R
E
E
P
Q
D
I
Y
W
L
A
Q
C
L
Y
Site 6
Y69
S
R
K
L
D
K
L
Y
E
A
C
R
Y
L
A
Site 7
Y74
K
L
Y
E
A
C
R
Y
L
A
A
R
C
H
Y
Site 8
Y81
Y
L
A
A
R
C
H
Y
A
A
K
E
H
Q
Q
Site 9
Y107
N
K
R
L
F
E
K
Y
L
K
D
E
S
G
F
Site 10
S112
E
K
Y
L
K
D
E
S
G
F
K
D
P
S
S
Site 11
S118
E
S
G
F
K
D
P
S
S
D
W
E
M
S
Q
Site 12
S119
S
G
F
K
D
P
S
S
D
W
E
M
S
Q
S
Site 13
S124
P
S
S
D
W
E
M
S
Q
S
S
I
K
S
S
Site 14
S126
S
D
W
E
M
S
Q
S
S
I
K
S
S
I
C
Site 15
S127
D
W
E
M
S
Q
S
S
I
K
S
S
I
C
L
Site 16
S131
S
Q
S
S
I
K
S
S
I
C
L
L
R
G
K
Site 17
T147
Y
D
A
L
D
N
R
T
L
A
T
Y
S
Y
K
Site 18
Y151
D
N
R
T
L
A
T
Y
S
Y
K
E
A
L
K
Site 19
S187
E
E
K
E
L
L
E
S
L
P
L
S
K
L
C
Site 20
S191
L
L
E
S
L
P
L
S
K
L
C
N
E
E
Q
Site 21
Y212
F
E
N
K
L
K
K
Y
N
K
P
S
E
T
V
Site 22
S216
L
K
K
Y
N
K
P
S
E
T
V
I
P
E
S
Site 23
T218
K
Y
N
K
P
S
E
T
V
I
P
E
S
V
D
Site 24
S223
S
E
T
V
I
P
E
S
V
D
G
L
Q
E
N
Site 25
S236
E
N
L
D
V
V
V
S
L
A
E
R
H
Y
Y
Site 26
Y242
V
S
L
A
E
R
H
Y
Y
N
C
D
F
K
M
Site 27
T254
F
K
M
C
Y
K
L
T
S
V
V
M
E
K
D
Site 28
S266
E
K
D
P
F
H
A
S
C
L
P
V
H
I
G
Site 29
Y286
N
K
A
N
E
L
F
Y
L
S
H
K
L
V
D
Site 30
Y295
S
H
K
L
V
D
L
Y
P
S
N
P
V
S
W
Site 31
Y322
K
N
E
H
A
R
R
Y
L
S
K
A
T
T
L
Site 32
S324
E
H
A
R
R
Y
L
S
K
A
T
T
L
E
K
Site 33
T328
R
Y
L
S
K
A
T
T
L
E
K
T
Y
G
P
Site 34
T332
K
A
T
T
L
E
K
T
Y
G
P
A
W
I
A
Site 35
T381
I
G
L
E
Y
G
L
T
N
N
S
K
L
A
E
Site 36
S396
R
F
F
S
Q
A
L
S
I
A
P
E
D
P
F
Site 37
T440
K
A
I
G
N
E
V
T
V
D
K
W
E
P
L
Site 38
Y461
V
C
R
K
L
K
K
Y
A
E
A
L
D
Y
H
Site 39
Y467
K
Y
A
E
A
L
D
Y
H
R
Q
A
L
V
L
Site 40
S483
P
Q
N
A
S
T
Y
S
A
I
G
Y
I
H
S
Site 41
S490
S
A
I
G
Y
I
H
S
L
M
G
N
F
E
N
Site 42
T513
L
G
L
R
R
D
D
T
F
S
V
T
M
L
G
Site 43
S515
L
R
R
D
D
T
F
S
V
T
M
L
G
H
C
Site 44
Y526
L
G
H
C
I
E
M
Y
I
G
D
S
E
A
Y
Site 45
Y545
I
K
D
K
L
K
C
Y
D
F
D
V
H
T
M
Site 46
T554
F
D
V
H
T
M
K
T
L
K
N
I
I
S
P
Site 47
S560
K
T
L
K
N
I
I
S
P
P
W
D
F
R
E
Site 48
T581
T
A
E
E
T
G
L
T
P
L
E
T
S
R
K
Site 49
T585
T
G
L
T
P
L
E
T
S
R
K
T
P
D
S
Site 50
S586
G
L
T
P
L
E
T
S
R
K
T
P
D
S
R
Site 51
T589
P
L
E
T
S
R
K
T
P
D
S
R
P
S
L
Site 52
S592
T
S
R
K
T
P
D
S
R
P
S
L
E
E
T
Site 53
S595
K
T
P
D
S
R
P
S
L
E
E
T
F
E
I
Site 54
T599
S
R
P
S
L
E
E
T
F
E
I
E
M
N
E
Site 55
S607
F
E
I
E
M
N
E
S
D
M
M
L
E
T
S
Site 56
S614
S
D
M
M
L
E
T
S
M
S
D
H
S
T
_
Site 57
S616
M
M
L
E
T
S
M
S
D
H
S
T
_
_
_
Site 58
S619
E
T
S
M
S
D
H
S
T
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation