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Updated November 2019
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Protein Info
Short Name:
TCOF1
Full Name:
Treacle protein
Alias:
TCOF; Treacher Collins syndrome protein; Treacher Collins-Franceschetti syndrome 1; Treacle
Type:
Transcription protein, coactivator/corepressor
Mass (Da):
152104
Number AA:
1488
UniProt ID:
Q13428
International Prot ID:
IPI00298696
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005215
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0001501
GO:0006810
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
H
H
L
L
R
A
G
Y
V
R
A
A
R
E
V
Site 2
Y50
P
V
T
L
L
D
I
Y
T
H
W
Q
Q
T
S
Site 3
T51
V
T
L
L
D
I
Y
T
H
W
Q
Q
T
S
E
Site 4
T76
A
A
L
Q
A
K
K
T
R
V
S
D
P
I
S
Site 5
S79
Q
A
K
K
T
R
V
S
D
P
I
S
T
S
E
Site 6
S83
T
R
V
S
D
P
I
S
T
S
E
S
S
E
E
Site 7
T84
R
V
S
D
P
I
S
T
S
E
S
S
E
E
E
Site 8
S85
V
S
D
P
I
S
T
S
E
S
S
E
E
E
E
Site 9
S87
D
P
I
S
T
S
E
S
S
E
E
E
E
E
A
Site 10
S88
P
I
S
T
S
E
S
S
E
E
E
E
E
A
E
Site 11
T102
E
A
E
T
A
K
A
T
P
R
L
A
S
T
N
Site 12
S107
K
A
T
P
R
L
A
S
T
N
S
S
V
L
G
Site 13
T108
A
T
P
R
L
A
S
T
N
S
S
V
L
G
A
Site 14
S110
P
R
L
A
S
T
N
S
S
V
L
G
A
D
L
Site 15
S111
R
L
A
S
T
N
S
S
V
L
G
A
D
L
P
Site 16
S120
L
G
A
D
L
P
S
S
M
K
E
K
A
K
A
Site 17
T135
E
T
E
K
A
G
K
T
G
N
S
M
P
H
P
Site 18
S138
K
A
G
K
T
G
N
S
M
P
H
P
A
T
G
Site 19
T144
N
S
M
P
H
P
A
T
G
K
T
V
A
N
L
Site 20
T147
P
H
P
A
T
G
K
T
V
A
N
L
L
S
G
Site 21
S153
K
T
V
A
N
L
L
S
G
K
S
P
R
K
S
Site 22
S156
A
N
L
L
S
G
K
S
P
R
K
S
A
E
P
Site 23
S160
S
G
K
S
P
R
K
S
A
E
P
S
A
N
T
Site 24
S164
P
R
K
S
A
E
P
S
A
N
T
T
L
V
S
Site 25
T167
S
A
E
P
S
A
N
T
T
L
V
S
E
T
E
Site 26
T168
A
E
P
S
A
N
T
T
L
V
S
E
T
E
E
Site 27
S171
S
A
N
T
T
L
V
S
E
T
E
E
E
G
S
Site 28
T173
N
T
T
L
V
S
E
T
E
E
E
G
S
V
P
Site 29
S178
S
E
T
E
E
E
G
S
V
P
A
F
G
A
A
Site 30
S192
A
A
K
P
G
M
V
S
A
G
Q
A
D
S
S
Site 31
S198
V
S
A
G
Q
A
D
S
S
S
E
D
T
S
S
Site 32
S199
S
A
G
Q
A
D
S
S
S
E
D
T
S
S
S
Site 33
S200
A
G
Q
A
D
S
S
S
E
D
T
S
S
S
S
Site 34
T203
A
D
S
S
S
E
D
T
S
S
S
S
D
E
T
Site 35
S204
D
S
S
S
E
D
T
S
S
S
S
D
E
T
D
Site 36
S205
S
S
S
E
D
T
S
S
S
S
D
E
T
D
V
Site 37
S206
S
S
E
D
T
S
S
S
S
D
E
T
D
V
E
Site 38
S207
S
E
D
T
S
S
S
S
D
E
T
D
V
E
G
Site 39
T210
T
S
S
S
S
D
E
T
D
V
E
G
K
P
S
Site 40
S217
T
D
V
E
G
K
P
S
V
K
P
A
Q
V
K
Site 41
S227
P
A
Q
V
K
A
S
S
V
S
T
K
E
S
P
Site 42
S229
Q
V
K
A
S
S
V
S
T
K
E
S
P
A
R
Site 43
T230
V
K
A
S
S
V
S
T
K
E
S
P
A
R
K
Site 44
S233
S
S
V
S
T
K
E
S
P
A
R
K
A
A
P
Site 45
T249
P
G
K
V
G
D
V
T
P
Q
V
K
G
G
A
Site 46
S270
A
K
K
P
E
E
E
S
E
S
S
E
E
G
S
Site 47
S272
K
P
E
E
E
S
E
S
S
E
E
G
S
E
S
Site 48
S273
P
E
E
E
S
E
S
S
E
E
G
S
E
S
E
Site 49
S277
S
E
S
S
E
E
G
S
E
S
E
E
E
A
P
Site 50
S279
S
S
E
E
G
S
E
S
E
E
E
A
P
A
G
Site 51
S289
E
A
P
A
G
T
R
S
Q
V
K
A
S
E
K
Site 52
S304
I
L
Q
V
R
A
A
S
A
P
A
K
G
T
P
Site 53
T310
A
S
A
P
A
K
G
T
P
G
K
G
A
T
P
Site 54
T316
G
T
P
G
K
G
A
T
P
A
P
P
G
K
A
Site 55
S328
G
K
A
G
A
V
A
S
Q
T
K
A
G
K
P
Site 56
T330
A
G
A
V
A
S
Q
T
K
A
G
K
P
E
E
Site 57
S339
A
G
K
P
E
E
D
S
E
S
S
S
E
E
S
Site 58
S341
K
P
E
E
D
S
E
S
S
S
E
E
S
S
D
Site 59
S342
P
E
E
D
S
E
S
S
S
E
E
S
S
D
S
Site 60
S343
E
E
D
S
E
S
S
S
E
E
S
S
D
S
E
Site 61
S346
S
E
S
S
S
E
E
S
S
D
S
E
E
E
T
Site 62
S347
E
S
S
S
E
E
S
S
D
S
E
E
E
T
P
Site 63
S349
S
S
E
E
S
S
D
S
E
E
E
T
P
A
A
Site 64
T353
S
S
D
S
E
E
E
T
P
A
A
K
A
L
L
Site 65
S365
A
L
L
Q
A
K
A
S
G
K
T
S
Q
V
G
Site 66
T368
Q
A
K
A
S
G
K
T
S
Q
V
G
A
A
S
Site 67
S369
A
K
A
S
G
K
T
S
Q
V
G
A
A
S
A
Site 68
S375
T
S
Q
V
G
A
A
S
A
P
A
K
E
S
P
Site 69
S381
A
S
A
P
A
K
E
S
P
R
K
G
A
A
P
Site 70
T394
A
P
A
P
P
G
K
T
G
P
A
V
A
K
A
Site 71
S410
A
G
K
R
E
E
D
S
Q
S
S
S
E
E
S
Site 72
S412
K
R
E
E
D
S
Q
S
S
S
E
E
S
D
S
Site 73
S413
R
E
E
D
S
Q
S
S
S
E
E
S
D
S
E
Site 74
S414
E
E
D
S
Q
S
S
S
E
E
S
D
S
E
E
Site 75
S417
S
Q
S
S
S
E
E
S
D
S
E
E
E
A
P
Site 76
S419
S
S
S
E
E
S
D
S
E
E
E
A
P
A
Q
Site 77
S440
A
P
Q
V
R
A
A
S
A
P
A
K
E
S
P
Site 78
T459
A
P
A
P
P
R
K
T
G
P
A
A
A
Q
V
Site 79
S475
V
G
K
Q
E
E
D
S
R
S
S
S
E
E
S
Site 80
S477
K
Q
E
E
D
S
R
S
S
S
E
E
S
D
S
Site 81
S478
Q
E
E
D
S
R
S
S
S
E
E
S
D
S
D
Site 82
S479
E
E
D
S
R
S
S
S
E
E
S
D
S
D
R
Site 83
S482
S
R
S
S
S
E
E
S
D
S
D
R
E
A
L
Site 84
S484
S
S
S
E
E
S
D
S
D
R
E
A
L
A
A
Site 85
S503
Q
V
K
P
L
G
K
S
P
Q
V
K
P
A
S
Site 86
S510
S
P
Q
V
K
P
A
S
T
M
G
M
G
P
L
Site 87
T533
P
G
K
V
G
P
A
T
P
S
A
Q
V
G
K
Site 88
S545
V
G
K
W
E
E
D
S
E
S
S
S
E
E
S
Site 89
S547
K
W
E
E
D
S
E
S
S
S
E
E
S
S
D
Site 90
S548
W
E
E
D
S
E
S
S
S
E
E
S
S
D
S
Site 91
S549
E
E
D
S
E
S
S
S
E
E
S
S
D
S
S
Site 92
S552
S
E
S
S
S
E
E
S
S
D
S
S
D
G
E
Site 93
S553
E
S
S
S
E
E
S
S
D
S
S
D
G
E
V
Site 94
S555
S
S
E
E
S
S
D
S
S
D
G
E
V
P
T
Site 95
S556
S
E
E
S
S
D
S
S
D
G
E
V
P
T
A
Site 96
S571
V
A
P
A
Q
E
K
S
L
G
N
I
L
Q
A
Site 97
T581
N
I
L
Q
A
K
P
T
S
S
P
A
K
G
P
Site 98
S582
I
L
Q
A
K
P
T
S
S
P
A
K
G
P
P
Site 99
S583
L
Q
A
K
P
T
S
S
P
A
K
G
P
P
Q
Site 100
S608
A
E
K
P
M
D
N
S
E
S
S
E
E
S
S
Site 101
S610
K
P
M
D
N
S
E
S
S
E
E
S
S
D
S
Site 102
S611
P
M
D
N
S
E
S
S
E
E
S
S
D
S
A
Site 103
S614
N
S
E
S
S
E
E
S
S
D
S
A
D
S
E
Site 104
S615
S
E
S
S
E
E
S
S
D
S
A
D
S
E
E
Site 105
S617
S
S
E
E
S
S
D
S
A
D
S
E
E
A
P
Site 106
S620
E
S
S
D
S
A
D
S
E
E
A
P
A
A
M
Site 107
T641
P
A
L
K
I
P
Q
T
K
A
C
P
K
K
T
Site 108
T663
V
A
P
V
R
V
G
T
Q
P
P
R
K
A
G
Site 109
T673
P
R
K
A
G
T
A
T
S
P
A
G
S
S
P
Site 110
S674
R
K
A
G
T
A
T
S
P
A
G
S
S
P
A
Site 111
S678
T
A
T
S
P
A
G
S
S
P
A
V
A
G
G
Site 112
S679
A
T
S
P
A
G
S
S
P
A
V
A
G
G
T
Site 113
T686
S
P
A
V
A
G
G
T
Q
R
P
A
E
D
S
Site 114
S693
T
Q
R
P
A
E
D
S
S
S
S
E
E
S
D
Site 115
S694
Q
R
P
A
E
D
S
S
S
S
E
E
S
D
S
Site 116
S695
R
P
A
E
D
S
S
S
S
E
E
S
D
S
E
Site 117
S696
P
A
E
D
S
S
S
S
E
E
S
D
S
E
E
Site 118
S699
D
S
S
S
S
E
E
S
D
S
E
E
E
K
T
Site 119
S701
S
S
S
E
E
S
D
S
E
E
E
K
T
G
L
Site 120
T706
S
D
S
E
E
E
K
T
G
L
A
V
T
V
G
Site 121
S734
A
S
V
P
V
K
G
S
L
G
Q
G
T
A
P
Site 122
T739
K
G
S
L
G
Q
G
T
A
P
V
L
P
G
K
Site 123
S762
K
A
E
K
Q
E
D
S
E
S
S
E
E
E
S
Site 124
S764
E
K
Q
E
D
S
E
S
S
E
E
E
S
D
S
Site 125
S765
K
Q
E
D
S
E
S
S
E
E
E
S
D
S
E
Site 126
S769
S
E
S
S
E
E
E
S
D
S
E
E
A
A
A
Site 127
S771
S
S
E
E
E
S
D
S
E
E
A
A
A
S
P
Site 128
S777
D
S
E
E
A
A
A
S
P
A
Q
V
K
T
S
Site 129
T783
A
S
P
A
Q
V
K
T
S
V
K
K
T
Q
A
Site 130
S784
S
P
A
Q
V
K
T
S
V
K
K
T
Q
A
K
Site 131
T788
V
K
T
S
V
K
K
T
Q
A
K
A
N
P
A
Site 132
S801
P
A
A
A
R
A
P
S
A
K
G
T
I
S
A
Site 133
T805
R
A
P
S
A
K
G
T
I
S
A
P
G
K
V
Site 134
S807
P
S
A
K
G
T
I
S
A
P
G
K
V
V
T
Site 135
S823
A
A
Q
A
K
Q
R
S
P
S
K
A
R
P
P
Site 136
S825
A
A
Q
A
K
Q
R
S
P
S
K
A
R
P
P
Site 137
S837
P
V
R
N
P
Q
N
S
T
V
L
A
R
G
P
Site 138
S868
Q
T
G
P
E
E
D
S
G
S
S
E
E
E
S
Site 139
S870
G
P
E
E
D
S
G
S
S
E
E
E
S
D
S
Site 140
S871
A
T
A
A
Q
A
Q
T
G
P
E
E
D
S
G
Site 141
S875
S
G
S
S
E
E
E
S
D
S
E
E
E
A
E
Site 142
S877
S
S
E
E
E
S
D
S
E
E
E
A
E
T
L
Site 143
T883
D
S
E
E
E
A
E
T
L
A
Q
A
K
P
S
Site 144
S890
I
F
V
D
P
N
R
S
P
A
G
P
A
A
T
Site 145
S906
A
L
A
P
A
K
E
S
P
R
K
G
A
A
P
Site 146
T914
P
R
K
G
A
A
P
T
P
P
G
K
T
G
P
Site 147
S922
S
T
A
R
S
S
S
S
E
S
E
D
E
D
V
Site 148
S932
Q
A
G
K
Q
D
D
S
G
S
S
S
E
E
S
Site 149
S934
G
K
Q
D
D
S
G
S
S
S
E
E
S
D
S
Site 150
S935
G
K
Q
D
D
S
G
S
S
S
E
E
S
D
S
Site 151
S936
Q
D
D
S
G
S
S
S
E
E
S
D
S
D
G
Site 152
S939
S
G
S
S
S
E
E
S
D
S
D
G
E
A
P
Site 153
S941
S
S
S
E
E
S
D
S
D
G
E
A
P
A
A
Site 154
S967
I
F
V
D
P
N
R
S
P
A
G
P
A
A
T
Site 155
T974
S
P
A
G
P
A
A
T
P
A
Q
A
Q
A
A
Site 156
S982
P
A
Q
A
Q
A
A
S
T
P
R
K
A
R
A
Site 157
T983
A
Q
A
Q
A
A
S
T
P
R
K
A
R
A
S
Site 158
S990
T
P
R
K
A
R
A
S
E
S
T
A
R
S
S
Site 159
S992
R
K
A
R
A
S
E
S
T
A
R
S
S
S
S
Site 160
T993
K
A
R
A
S
E
S
T
A
R
S
S
S
S
E
Site 161
S996
A
S
E
S
T
A
R
S
S
S
S
E
S
E
D
Site 162
S997
S
E
S
T
A
R
S
S
S
S
E
S
E
D
E
Site 163
S998
S
E
S
T
A
R
S
S
S
S
E
S
E
D
E
Site 164
S999
S
T
A
R
S
S
S
S
E
S
E
D
E
D
V
Site 165
S1001
A
R
S
S
S
S
E
S
E
D
E
D
V
I
P
Site 166
T1014
I
P
A
T
Q
C
L
T
P
G
I
R
T
N
V
Site 167
T1023
G
I
R
T
N
V
V
T
M
P
T
A
H
P
R
Site 168
S1036
P
R
I
A
P
K
A
S
M
A
G
A
S
S
S
Site 169
S1041
K
A
S
M
A
G
A
S
S
S
K
E
S
S
R
Site 170
S1042
A
S
M
A
G
A
S
S
S
K
E
S
S
R
I
Site 171
S1043
S
M
A
G
A
S
S
S
K
E
S
S
R
I
S
Site 172
S1046
G
A
S
S
S
K
E
S
S
R
I
S
D
G
K
Site 173
S1047
A
S
S
S
K
E
S
S
R
I
S
D
G
K
K
Site 174
S1050
S
K
E
S
S
R
I
S
D
G
K
K
Q
E
G
Site 175
T1060
K
K
Q
E
G
P
A
T
Q
V
S
K
K
N
P
Site 176
S1063
E
G
P
A
T
Q
V
S
K
K
N
P
A
S
L
Site 177
S1069
V
S
K
K
N
P
A
S
L
P
L
T
Q
A
A
Site 178
T1094
A
Q
P
P
V
A
R
T
Q
P
S
S
G
V
D
Site 179
S1097
P
V
A
R
T
Q
P
S
S
G
V
D
S
A
V
Site 180
S1098
V
A
R
T
Q
P
S
S
G
V
D
S
A
V
G
Site 181
S1102
Q
P
S
S
G
V
D
S
A
V
G
T
L
P
A
Site 182
T1106
G
V
D
S
A
V
G
T
L
P
A
T
S
P
Q
Site 183
T1110
A
V
G
T
L
P
A
T
S
P
Q
S
T
S
V
Site 184
S1111
V
G
T
L
P
A
T
S
P
Q
S
T
S
V
Q
Site 185
S1114
L
P
A
T
S
P
Q
S
T
S
V
Q
A
K
G
Site 186
T1115
P
A
T
S
P
Q
S
T
S
V
Q
A
K
G
T
Site 187
S1116
A
T
S
P
Q
S
T
S
V
Q
A
K
G
T
N
Site 188
S1142
Q
A
T
K
A
P
E
S
S
D
D
S
E
D
S
Site 189
S1143
A
T
K
A
P
E
S
S
D
D
S
E
D
S
S
Site 190
S1146
A
P
E
S
S
D
D
S
E
D
S
S
D
S
S
Site 191
S1149
S
S
D
D
S
E
D
S
S
D
S
S
S
G
S
Site 192
S1150
S
D
D
S
E
D
S
S
D
S
S
S
G
S
E
Site 193
S1152
D
S
E
D
S
S
D
S
S
S
G
S
E
E
D
Site 194
S1153
V
E
E
T
A
A
E
S
S
E
D
D
V
V
A
Site 195
S1154
E
E
T
A
A
E
S
S
E
D
D
V
V
A
P
Site 196
S1156
S
S
D
S
S
S
G
S
E
E
D
G
E
G
P
Site 197
S1168
E
G
P
Q
G
A
K
S
A
H
T
L
G
P
T
Site 198
T1171
Q
G
A
K
S
A
H
T
L
G
P
T
P
S
R
Site 199
T1175
G
Y
M
T
P
G
L
T
P
A
N
S
Q
A
S
Site 200
S1177
H
T
L
G
P
T
P
S
R
T
E
T
L
V
E
Site 201
T1179
L
G
P
T
P
S
R
T
E
T
L
V
E
E
T
Site 202
T1181
P
T
P
S
R
T
E
T
L
V
E
E
T
A
A
Site 203
T1186
T
E
T
L
V
E
E
T
A
A
E
S
S
E
D
Site 204
S1190
K
A
T
P
K
L
D
S
S
P
S
V
S
S
T
Site 205
S1191
A
T
P
K
L
D
S
S
P
S
V
S
S
T
L
Site 206
S1199
E
D
D
V
V
A
P
S
Q
S
L
L
S
G
Y
Site 207
S1204
A
P
S
Q
S
L
L
S
G
Y
M
T
P
G
L
Site 208
Y1206
S
Q
S
L
L
S
G
Y
M
T
P
G
L
T
P
Site 209
T1208
S
L
L
S
G
Y
M
T
P
G
L
T
P
A
N
Site 210
T1212
G
Y
M
T
P
G
L
T
P
A
N
S
Q
A
S
Site 211
S1216
P
G
L
T
P
A
N
S
Q
A
S
K
A
T
P
Site 212
S1219
T
P
A
N
S
Q
A
S
K
A
T
P
K
L
D
Site 213
T1222
N
S
Q
A
S
K
A
T
P
K
L
D
S
S
P
Site 214
S1227
K
A
T
P
K
L
D
S
S
P
S
V
S
S
T
Site 215
S1228
A
T
P
K
L
D
S
S
P
S
V
S
S
T
L
Site 216
S1230
P
K
L
D
S
S
P
S
V
S
S
T
L
A
A
Site 217
S1232
L
D
S
S
P
S
V
S
S
T
L
A
A
K
D
Site 218
T1234
S
S
P
S
V
S
S
T
L
A
A
K
D
D
P
Site 219
S1257
Q
Q
A
A
G
M
L
S
P
K
T
G
G
K
E
Site 220
T1260
A
G
M
L
S
P
K
T
G
G
K
E
A
A
S
Site 221
T1270
K
E
A
A
S
G
T
T
P
Q
K
S
R
K
P
Site 222
S1274
S
G
T
T
P
Q
K
S
R
K
P
K
K
G
A
Site 223
S1287
G
A
G
N
P
Q
A
S
T
L
A
L
Q
S
N
Site 224
T1288
A
G
N
P
Q
A
S
T
L
A
L
Q
S
N
I
Site 225
T1296
L
A
L
Q
S
N
I
T
Q
C
L
L
G
Q
P
Site 226
S1314
N
E
A
Q
V
Q
A
S
V
V
K
V
L
T
E
Site 227
T1320
G
D
Q
P
A
A
R
T
P
R
S
K
K
K
K
Site 228
T1333
E
R
K
K
V
V
D
T
T
K
E
S
S
R
K
Site 229
T1334
R
K
K
V
V
D
T
T
K
E
S
S
R
K
G
Site 230
S1338
V
D
T
T
K
E
S
S
R
K
G
W
E
S
R
Site 231
S1344
S
S
R
K
G
W
E
S
R
K
R
K
L
S
G
Site 232
S1350
E
S
R
K
R
K
L
S
G
D
Q
P
A
A
R
Site 233
T1358
G
D
Q
P
A
A
R
T
P
R
S
K
K
K
K
Site 234
S1361
P
A
A
R
T
P
R
S
K
K
K
K
K
L
G
Site 235
S1376
A
G
E
G
G
E
A
S
V
S
P
E
K
T
S
Site 236
S1378
E
G
G
E
A
S
V
S
P
E
K
T
S
T
T
Site 237
T1382
A
S
V
S
P
E
K
T
S
T
T
S
K
G
K
Site 238
T1384
V
S
P
E
K
T
S
T
T
S
K
G
K
A
K
Site 239
S1386
P
E
K
T
S
T
T
S
K
G
K
A
K
R
D
Site 240
S1396
K
A
K
R
D
K
A
S
G
D
V
K
E
K
K
Site 241
S1407
K
E
K
K
G
K
G
S
L
G
S
Q
G
A
K
Site 242
S1410
K
G
K
G
S
L
G
S
Q
G
A
K
D
E
P
Site 243
T1427
E
L
Q
K
G
M
G
T
V
E
G
G
D
Q
S
Site 244
S1434
T
V
E
G
G
D
Q
S
N
P
K
S
K
K
E
Site 245
S1438
G
D
Q
S
N
P
K
S
K
K
E
K
K
K
S
Site 246
S1445
S
K
K
E
K
K
K
S
D
K
R
K
K
D
K
Site 247
S1465
K
K
K
A
K
K
A
S
T
K
D
S
E
S
P
Site 248
S1469
K
K
A
S
T
K
D
S
E
S
P
S
Q
K
K
Site 249
S1471
A
S
T
K
D
S
E
S
P
S
Q
K
K
K
K
Site 250
S1473
T
K
D
S
E
S
P
S
Q
K
K
K
K
K
K
Site 251
T1483
K
K
K
K
K
K
K
T
A
E
Q
T
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation