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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R1A
Full Name:
Protein phosphatase 1 regulatory subunit 1A
Alias:
I-1; Inhibitor 1; IPP1; PPR1A
Type:
Protein phosphatase inhibitor protein
Mass (Da):
18939
Number AA:
171
UniProt ID:
Q13522
International Prot ID:
IPI00299014
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004865
PhosphoSite+
KinaseNET
Biological Process:
GO:0005977
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
Q
D
N
S
P
R
K
I
Q
F
T
Site 2
T13
S
P
R
K
I
Q
F
T
V
P
L
L
E
P
H
Site 3
T35
Q
I
R
R
R
R
P
T
P
A
T
L
V
L
T
Site 4
T38
R
R
R
P
T
P
A
T
L
V
L
T
S
D
Q
Site 5
T42
T
P
A
T
L
V
L
T
S
D
Q
S
S
P
E
Site 6
S43
P
A
T
L
V
L
T
S
D
Q
S
S
P
E
I
Site 7
S46
L
V
L
T
S
D
Q
S
S
P
E
I
D
E
D
Site 8
S47
V
L
T
S
D
Q
S
S
P
E
I
D
E
D
R
Site 9
S62
I
P
N
P
H
L
K
S
T
L
A
M
S
P
R
Site 10
T63
P
N
P
H
L
K
S
T
L
A
M
S
P
R
Q
Site 11
S67
L
K
S
T
L
A
M
S
P
R
Q
R
K
K
M
Site 12
T75
P
R
Q
R
K
K
M
T
R
I
T
P
T
M
K
Site 13
T78
R
K
K
M
T
R
I
T
P
T
M
K
E
L
Q
Site 14
T110
G
A
A
E
S
T
G
T
Q
E
S
R
P
P
G
Site 15
S113
E
S
T
G
T
Q
E
S
R
P
P
G
I
P
D
Site 16
T121
R
P
P
G
I
P
D
T
E
V
E
S
R
L
G
Site 17
S125
I
P
D
T
E
V
E
S
R
L
G
T
S
G
T
Site 18
T129
E
V
E
S
R
L
G
T
S
G
T
A
K
K
T
Site 19
T132
S
R
L
G
T
S
G
T
A
K
K
T
A
E
C
Site 20
T136
T
S
G
T
A
K
K
T
A
E
C
I
P
K
T
Site 21
T143
T
A
E
C
I
P
K
T
H
E
R
G
S
K
E
Site 22
S148
P
K
T
H
E
R
G
S
K
E
P
S
T
K
E
Site 23
S152
E
R
G
S
K
E
P
S
T
K
E
P
S
T
H
Site 24
T153
R
G
S
K
E
P
S
T
K
E
P
S
T
H
I
Site 25
S157
E
P
S
T
K
E
P
S
T
H
I
P
P
L
D
Site 26
T158
P
S
T
K
E
P
S
T
H
I
P
P
L
D
S
Site 27
S165
T
H
I
P
P
L
D
S
K
G
A
N
S
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation