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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TUBA3C
Full Name:
Tubulin alpha-3C/D chain
Alias:
Alpha-tubulin 2; Alpha-tubulin 3C/D; BA408E5.3; SLBP; TBA2; TBA3C; TUBA2; Tubulin alpha-2 chain; Tubulin, alpha 3c; Tubulin, alpha-2
Type:
Cytoskeletal protein
Mass (Da):
49960
Number AA:
450
UniProt ID:
Q13748
International Prot ID:
IPI00179709
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
GO:0051258
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
G
N
A
C
W
E
L
Y
C
L
E
H
G
I
Q
Site 2
S38
Q
P
D
G
Q
M
P
S
D
K
T
I
G
G
G
Site 3
T41
G
Q
M
P
S
D
K
T
I
G
G
G
D
D
S
Site 4
S48
T
I
G
G
G
D
D
S
F
N
T
F
F
S
E
Site 5
T51
G
G
D
D
S
F
N
T
F
F
S
E
T
G
A
Site 6
S54
D
S
F
N
T
F
F
S
E
T
G
A
G
K
H
Site 7
T56
F
N
T
F
F
S
E
T
G
A
G
K
H
V
P
Site 8
T80
T
V
V
D
E
V
R
T
G
T
Y
R
Q
L
F
Site 9
T82
V
D
E
V
R
T
G
T
Y
R
Q
L
F
H
P
Site 10
Y83
D
E
V
R
T
G
T
Y
R
Q
L
F
H
P
E
Site 11
T94
F
H
P
E
Q
L
I
T
G
K
E
D
A
A
N
Site 12
Y103
K
E
D
A
A
N
N
Y
A
R
G
H
Y
T
I
Site 13
Y108
N
N
Y
A
R
G
H
Y
T
I
G
K
E
I
V
Site 14
T109
N
Y
A
R
G
H
Y
T
I
G
K
E
I
V
D
Site 15
S158
S
L
L
M
E
R
L
S
V
D
Y
G
K
K
S
Site 16
Y161
M
E
R
L
S
V
D
Y
G
K
K
S
K
L
E
Site 17
S165
S
V
D
Y
G
K
K
S
K
L
E
F
A
I
Y
Site 18
Y172
S
K
L
E
F
A
I
Y
P
A
P
Q
V
S
T
Site 19
Y185
S
T
A
V
V
E
P
Y
N
S
I
L
T
T
H
Site 20
S187
A
V
V
E
P
Y
N
S
I
L
T
T
H
T
T
Site 21
T190
E
P
Y
N
S
I
L
T
T
H
T
T
L
E
H
Site 22
T191
P
Y
N
S
I
L
T
T
H
T
T
L
E
H
S
Site 23
T193
N
S
I
L
T
T
H
T
T
L
E
H
S
D
C
Site 24
T194
S
I
L
T
T
H
T
T
L
E
H
S
D
C
A
Site 25
S198
T
H
T
T
L
E
H
S
D
C
A
F
M
V
D
Site 26
Y210
M
V
D
N
E
A
I
Y
D
I
C
R
R
N
L
Site 27
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Site 28
Y224
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
I
Site 29
T225
D
I
E
R
P
T
Y
T
N
L
N
R
L
I
G
Site 30
S236
R
L
I
G
Q
I
V
S
S
I
T
A
S
L
R
Site 31
S237
L
I
G
Q
I
V
S
S
I
T
A
S
L
R
F
Site 32
Y262
F
Q
T
N
L
V
P
Y
P
R
I
H
F
P
L
Site 33
T271
R
I
H
F
P
L
A
T
Y
A
P
V
I
S
A
Site 34
Y272
I
H
F
P
L
A
T
Y
A
P
V
I
S
A
E
Site 35
S277
A
T
Y
A
P
V
I
S
A
E
K
A
Y
H
E
Site 36
Y282
V
I
S
A
E
K
A
Y
H
E
Q
L
S
V
A
Site 37
S287
K
A
Y
H
E
Q
L
S
V
A
E
I
T
N
A
Site 38
T292
Q
L
S
V
A
E
I
T
N
A
C
F
E
P
A
Site 39
Y319
Y
M
A
C
C
M
L
Y
R
G
D
V
V
P
K
Site 40
T334
D
V
N
A
A
I
A
T
I
K
T
K
R
T
I
Site 41
T337
A
A
I
A
T
I
K
T
K
R
T
I
Q
F
V
Site 42
T340
A
T
I
K
T
K
R
T
I
Q
F
V
D
W
C
Site 43
T349
Q
F
V
D
W
C
P
T
G
F
K
V
G
I
N
Site 44
Y357
G
F
K
V
G
I
N
Y
Q
P
P
T
V
V
P
Site 45
T361
G
I
N
Y
Q
P
P
T
V
V
P
G
G
D
L
Site 46
S379
Q
R
A
V
C
M
L
S
N
T
T
A
I
A
E
Site 47
Y399
D
H
K
F
D
L
M
Y
A
K
R
A
F
V
H
Site 48
Y408
K
R
A
F
V
H
W
Y
V
G
E
G
M
E
E
Site 49
S419
G
M
E
E
G
E
F
S
E
A
R
E
D
L
A
Site 50
Y432
L
A
A
L
E
K
D
Y
E
E
V
G
V
D
S
Site 51
S439
Y
E
E
V
G
V
D
S
V
E
A
E
A
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation