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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GANAB
Full Name:
Neutral alpha-glucosidase AB
Alias:
Alpha-glucosidase 2; G2AN; Glucosidase II alpha; Glucosidase II subunit alpha; Glucosidase, alpha; GluII; KIAA0088; Neutral AB; Neutral alpha-glucosidase AB
Type:
Glycan Metabolism - N-glycan biosynthesis; Endoplasmic reticulum; Hydrolase; EC 3.2.1.84
Mass (Da):
106855
Number AA:
944
UniProt ID:
Q14697
International Prot ID:
IPI00011454
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005783
GO:0042470
Uniprot
OncoNet
Molecular Function:
GO:0033919
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
R
R
R
R
S
W
A
S
L
V
L
A
F
L
G
Site 2
S36
I
T
L
A
V
D
R
S
N
F
K
T
C
E
E
Site 3
T40
V
D
R
S
N
F
K
T
C
E
E
S
S
F
C
Site 4
S45
F
K
T
C
E
E
S
S
F
C
K
R
Q
R
S
Site 5
S52
S
F
C
K
R
Q
R
S
I
R
P
G
L
S
P
Site 6
S58
R
S
I
R
P
G
L
S
P
Y
R
A
L
L
D
Site 7
S66
P
Y
R
A
L
L
D
S
L
Q
L
G
P
D
S
Site 8
T99
Q
G
L
Q
K
N
M
T
R
F
R
I
D
E
L
Site 9
Y113
L
E
P
R
R
P
R
Y
R
V
P
D
V
L
V
Site 10
S129
D
P
P
I
A
R
L
S
V
S
G
R
D
E
N
Site 11
S131
P
I
A
R
L
S
V
S
G
R
D
E
N
S
V
Site 12
S137
V
S
G
R
D
E
N
S
V
E
L
T
M
A
E
Site 13
T141
D
E
N
S
V
E
L
T
M
A
E
G
P
Y
K
Site 14
T152
G
P
Y
K
I
I
L
T
A
R
P
F
R
L
D
Site 15
S187
H
Q
R
A
P
R
V
S
Q
G
S
K
D
P
A
Site 16
S190
A
P
R
V
S
Q
G
S
K
D
P
A
E
G
D
Site 17
T204
D
G
A
Q
P
E
E
T
P
R
D
G
D
K
P
Site 18
T229
E
P
G
A
W
E
E
T
F
K
T
H
S
D
S
Site 19
T232
A
W
E
E
T
F
K
T
H
S
D
S
K
P
Y
Site 20
S234
E
E
T
F
K
T
H
S
D
S
K
P
Y
G
P
Site 21
S236
T
F
K
T
H
S
D
S
K
P
Y
G
P
M
S
Site 22
S243
S
K
P
Y
G
P
M
S
V
G
L
D
F
S
L
Site 23
Y257
L
P
G
M
E
H
V
Y
G
I
P
E
H
A
D
Site 24
T271
D
N
L
R
L
K
V
T
E
G
G
E
P
Y
R
Site 25
Y280
G
G
E
P
Y
R
L
Y
N
L
D
V
F
Q
Y
Site 26
Y287
Y
N
L
D
V
F
Q
Y
E
L
Y
N
P
M
A
Site 27
Y290
D
V
F
Q
Y
E
L
Y
N
P
M
A
L
Y
G
Site 28
S327
E
T
W
V
D
I
S
S
N
T
A
G
K
T
L
Site 29
T333
S
S
N
T
A
G
K
T
L
F
G
K
M
M
D
Site 30
Y341
L
F
G
K
M
M
D
Y
L
Q
G
S
G
E
T
Site 31
T351
G
S
G
E
T
P
Q
T
D
V
R
W
M
S
E
Site 32
S357
Q
T
D
V
R
W
M
S
E
T
G
I
I
D
V
Site 33
Y379
I
S
D
V
F
R
Q
Y
A
S
L
T
G
T
Q
Site 34
S381
D
V
F
R
Q
Y
A
S
L
T
G
T
Q
A
L
Site 35
S393
Q
A
L
P
P
L
F
S
L
G
Y
H
Q
S
R
Site 36
Y396
P
P
L
F
S
L
G
Y
H
Q
S
R
W
N
Y
Site 37
Y403
Y
H
Q
S
R
W
N
Y
R
D
E
A
D
V
L
Site 38
Y438
E
H
A
D
G
K
R
Y
F
T
W
D
P
S
R
Site 39
T440
A
D
G
K
R
Y
F
T
W
D
P
S
R
F
P
Site 40
T451
S
R
F
P
Q
P
R
T
M
L
E
R
L
A
S
Site 41
S458
T
M
L
E
R
L
A
S
K
R
R
K
L
V
A
Site 42
S475
D
P
H
I
K
V
D
S
G
Y
R
V
H
E
E
Site 43
Y477
H
I
K
V
D
S
G
Y
R
V
H
E
E
L
R
Site 44
Y489
E
L
R
N
L
G
L
Y
V
K
T
R
D
G
S
Site 45
T492
N
L
G
L
Y
V
K
T
R
D
G
S
D
Y
E
Site 46
Y498
K
T
R
D
G
S
D
Y
E
G
W
C
W
P
G
Site 47
Y509
C
W
P
G
S
A
G
Y
P
D
F
T
N
P
T
Site 48
Y530
N
M
F
S
Y
D
N
Y
E
G
S
A
P
N
L
Site 49
Y563
M
L
K
D
A
Q
H
Y
G
G
W
E
H
R
D
Site 50
S591
A
D
G
L
R
Q
R
S
G
G
M
E
R
P
F
Site 51
Y664
P
E
L
L
V
R
W
Y
Q
M
G
A
Y
Q
P
Site 52
T681
R
A
H
A
H
L
D
T
G
R
R
E
P
W
L
Site 53
S691
R
E
P
W
L
L
P
S
Q
H
N
D
I
I
R
Site 54
S706
D
A
L
G
Q
R
Y
S
L
L
P
F
W
Y
T
Site 55
Y716
P
F
W
Y
T
L
L
Y
Q
A
H
R
E
G
I
Site 56
Y733
M
R
P
L
W
V
Q
Y
P
Q
D
V
T
T
F
Site 57
T739
Q
Y
P
Q
D
V
T
T
F
N
I
D
D
Q
Y
Site 58
Y768
G
A
H
G
V
Q
V
Y
L
P
G
Q
G
E
V
Site 59
Y777
P
G
Q
G
E
V
W
Y
D
I
Q
S
Y
Q
K
Site 60
T790
Q
K
H
H
G
P
Q
T
L
Y
L
P
V
T
L
Site 61
Y792
H
H
G
P
Q
T
L
Y
L
P
V
T
L
S
S
Site 62
T808
P
V
F
Q
R
G
G
T
I
V
P
R
W
M
R
Site 63
S819
R
W
M
R
V
R
R
S
S
E
C
M
K
D
D
Site 64
S820
W
M
R
V
R
R
S
S
E
C
M
K
D
D
P
Site 65
T851
L
F
L
D
D
G
H
T
F
N
Y
Q
T
R
Q
Site 66
Y854
D
D
G
H
T
F
N
Y
Q
T
R
Q
E
F
L
Site 67
S866
E
F
L
L
R
R
F
S
F
S
G
N
T
L
V
Site 68
T871
R
F
S
F
S
G
N
T
L
V
S
S
S
A
D
Site 69
S874
F
S
G
N
T
L
V
S
S
S
A
D
P
E
G
Site 70
S875
S
G
N
T
L
V
S
S
S
A
D
P
E
G
H
Site 71
S876
G
N
T
L
V
S
S
S
A
D
P
E
G
H
F
Site 72
T885
D
P
E
G
H
F
E
T
P
I
W
I
E
R
V
Site 73
S910
V
V
L
Q
T
K
G
S
P
E
S
R
L
S
F
Site 74
S913
Q
T
K
G
S
P
E
S
R
L
S
F
Q
H
D
Site 75
S916
G
S
P
E
S
R
L
S
F
Q
H
D
P
E
T
Site 76
T923
S
F
Q
H
D
P
E
T
S
V
L
V
L
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation