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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIF22
Full Name:
Kinesin-like protein KIF22
Alias:
KID; Kinesin family member 22; Kinesin-like 4; Kinesin-like DNA-binding; Kinesin-like DNA-binding protein; Kinesin-like KIF22; KNSL4; OBP-1; OBP-2
Type:
Motor protein; Microtubule binding protein
Mass (Da):
73262
Number AA:
665
UniProt ID:
Q14807
International Prot ID:
IPI00000769
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000776
GO:0005622
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0007017
GO:0007018
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
R
R
E
M
A
A
A
S
A
A
A
I
S
G
A
Site 2
S23
A
A
S
A
A
A
I
S
G
A
G
R
C
R
L
Site 3
S31
G
A
G
R
C
R
L
S
K
I
G
A
T
R
R
Site 4
T36
R
L
S
K
I
G
A
T
R
R
P
P
P
A
R
Site 5
T57
L
R
P
F
V
D
G
T
A
G
A
S
D
P
P
Site 6
S61
V
D
G
T
A
G
A
S
D
P
P
C
V
R
G
Site 7
S73
V
R
G
M
D
S
C
S
L
E
I
A
N
W
R
Site 8
Y88
N
H
Q
E
T
L
K
Y
Q
F
D
A
F
Y
G
Site 9
Y94
K
Y
Q
F
D
A
F
Y
G
E
R
S
T
Q
Q
Site 10
T99
A
F
Y
G
E
R
S
T
Q
Q
D
I
Y
A
G
Site 11
Y104
R
S
T
Q
Q
D
I
Y
A
G
S
V
Q
P
I
Site 12
S107
Q
Q
D
I
Y
A
G
S
V
Q
P
I
L
R
H
Site 13
Y126
Q
N
A
S
V
L
A
Y
G
P
T
G
A
G
K
Site 14
T129
S
V
L
A
Y
G
P
T
G
A
G
K
T
H
T
Site 15
T134
G
P
T
G
A
G
K
T
H
T
M
L
G
S
P
Site 16
T136
T
G
A
G
K
T
H
T
M
L
G
S
P
E
Q
Site 17
S140
K
T
H
T
M
L
G
S
P
E
Q
P
G
V
I
Site 18
T158
L
M
D
L
L
Q
L
T
R
E
E
G
A
E
G
Site 19
S171
E
G
R
P
W
A
L
S
V
T
M
S
Y
L
E
Site 20
Y180
T
M
S
Y
L
E
I
Y
Q
E
K
V
L
D
L
Site 21
S216
G
L
S
Q
K
P
I
S
S
F
A
D
F
E
R
Site 22
S217
L
S
Q
K
P
I
S
S
F
A
D
F
E
R
H
Site 23
S229
E
R
H
F
L
P
A
S
R
N
R
T
V
G
A
Site 24
T233
L
P
A
S
R
N
R
T
V
G
A
T
R
L
N
Site 25
T237
R
N
R
T
V
G
A
T
R
L
N
Q
R
S
S
Site 26
S243
A
T
R
L
N
Q
R
S
S
R
S
H
A
V
L
Site 27
S244
T
R
L
N
Q
R
S
S
R
S
H
A
V
L
L
Site 28
S246
L
N
Q
R
S
S
R
S
H
A
V
L
L
V
K
Site 29
Y271
R
Q
R
E
G
K
L
Y
L
I
D
L
A
G
S
Site 30
T284
G
S
E
D
N
R
R
T
G
N
K
G
L
R
L
Site 31
S294
K
G
L
R
L
K
E
S
G
A
I
N
T
S
L
Site 32
Y320
Q
G
L
P
R
V
P
Y
R
D
S
K
L
T
R
Site 33
S323
P
R
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Site 34
T326
P
Y
R
D
S
K
L
T
R
L
L
Q
D
S
L
Site 35
S332
L
T
R
L
L
Q
D
S
L
G
G
S
A
H
S
Site 36
T355
E
R
R
F
Y
L
D
T
V
S
A
L
N
F
A
Site 37
T374
E
V
I
N
R
P
F
T
N
E
S
L
Q
P
H
Site 38
S377
N
R
P
F
T
N
E
S
L
Q
P
H
A
L
G
Site 39
S412
P
E
E
E
E
I
G
S
P
E
P
M
A
A
P
Site 40
S421
E
P
M
A
A
P
A
S
A
S
Q
K
L
S
P
Site 41
S423
M
A
A
P
A
S
A
S
Q
K
L
S
P
L
Q
Site 42
S427
A
S
A
S
Q
K
L
S
P
L
Q
K
L
S
S
Site 43
S434
S
P
L
Q
K
L
S
S
M
D
P
A
M
L
E
Site 44
S445
A
M
L
E
R
L
L
S
L
D
R
L
L
A
S
Site 45
S452
S
L
D
R
L
L
A
S
Q
G
S
Q
G
A
P
Site 46
S455
R
L
L
A
S
Q
G
S
Q
G
A
P
L
L
S
Site 47
S462
S
Q
G
A
P
L
L
S
T
P
K
R
E
R
M
Site 48
T463
Q
G
A
P
L
L
S
T
P
K
R
E
R
M
V
Site 49
T474
E
R
M
V
L
M
K
T
V
E
E
K
D
L
E
Site 50
T487
L
E
I
E
R
L
K
T
K
Q
K
E
L
E
A
Site 51
T510
E
K
E
N
H
C
P
T
M
L
R
P
L
S
H
Site 52
S516
P
T
M
L
R
P
L
S
H
R
T
V
T
G
A
Site 53
T521
P
L
S
H
R
T
V
T
G
A
K
P
L
K
K
Site 54
S543
L
I
Q
E
Q
A
A
S
P
N
A
E
I
H
I
Site 55
S562
G
R
K
R
K
L
E
S
L
D
A
L
E
P
E
Site 56
S581
D
C
W
E
L
Q
I
S
P
E
L
L
A
H
G
Site 57
S600
L
D
L
L
N
E
G
S
A
R
D
L
R
S
L
Site 58
S606
G
S
A
R
D
L
R
S
L
Q
R
I
G
P
K
Site 59
S629
R
E
L
H
G
P
F
S
Q
V
E
D
L
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation