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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
p40phox
Full Name:
Neutrophil cytosol factor 4
Alias:
NCF4; NCF-4; Neutrophil cytosol factor 4; Neutrophil cytosolic factor 4, 40kDa; Neutrophil NADPH oxidase factor 4; P40phox; P40-phox; SH3 and PX domain-containing protein 4; SH3PXD4
Type:
Oxidoreductase
Mass (Da):
39032
Number AA:
339
UniProt ID:
Q15080
International Prot ID:
IPI00014338
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043020
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0046983
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0006955
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
Q
Q
L
R
A
E
S
D
F
E
Q
L
P
D
Site 2
Y53
K
T
K
G
G
S
K
Y
L
I
Y
R
R
Y
R
Site 3
Y56
G
G
S
K
Y
L
I
Y
R
R
Y
R
Q
F
H
Site 4
Y59
K
Y
L
I
Y
R
R
Y
R
Q
F
H
A
L
Q
Site 5
S77
E
E
R
F
G
P
D
S
K
S
S
A
L
A
C
Site 6
S79
R
F
G
P
D
S
K
S
S
A
L
A
C
T
L
Site 7
Y134
E
D
V
R
I
F
F
Y
Q
S
P
Y
D
S
E
Site 8
S136
V
R
I
F
F
Y
Q
S
P
Y
D
S
E
Q
V
Site 9
Y138
I
F
F
Y
Q
S
P
Y
D
S
E
Q
V
P
Q
Site 10
S140
F
Y
Q
S
P
Y
D
S
E
Q
V
P
Q
A
L
Site 11
T154
L
R
R
L
R
P
R
T
R
K
V
K
S
V
S
Site 12
S159
P
R
T
R
K
V
K
S
V
S
P
Q
G
N
S
Site 13
S161
T
R
K
V
K
S
V
S
P
Q
G
N
S
V
D
Site 14
T182
A
E
A
L
F
D
F
T
G
N
S
K
L
E
L
Site 15
S185
L
F
D
F
T
G
N
S
K
L
E
L
N
F
K
Site 16
T211
N
K
D
W
L
E
G
T
V
R
G
A
T
G
I
Site 17
Y243
P
T
N
W
L
R
C
Y
Y
Y
E
D
T
I
S
Site 18
Y245
N
W
L
R
C
Y
Y
Y
E
D
T
I
S
T
I
Site 19
S262
I
A
V
E
E
D
L
S
S
T
P
L
L
K
D
Site 20
S263
A
V
E
E
D
L
S
S
T
P
L
L
K
D
L
Site 21
T264
V
E
E
D
L
S
S
T
P
L
L
K
D
L
L
Site 22
T274
L
K
D
L
L
E
L
T
R
R
E
F
Q
R
E
Site 23
Y287
R
E
D
I
A
L
N
Y
R
D
A
E
G
D
L
Site 24
S315
R
Q
A
R
G
L
P
S
Q
K
R
L
F
P
W
Site 25
Y332
H
I
T
Q
K
D
N
Y
R
V
Y
N
T
M
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation