PhosphoNET

           
Protein Info 
   
Short Name:  PDA6
Full Name:  Protein disulfide-isomerase A6
Alias:  CaBP1; EC 5.3.4.1; PDIA6; Protein disulfide isomerase P5; Thioredoxin domain containing protein 7; TXNDC7
Type:  Enzyme, isomerase
Mass (Da):  48121
Number AA:  440
UniProt ID:  Q15084
International Prot ID:  IPI00644989
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005793  GO:0005788  GO:0042470 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0003756   PhosphoSite+ KinaseNET
Biological Process:  GO:0045454  GO:0006457   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S22LAVNGLYSSSDDVIE
Site 2S24VNGLYSSSDDVIELT
Site 3T31SDDVIELTPSNFNRE
Site 4S33DVIELTPSNFNREVI
Site 5S42FNREVIQSDSLWLVE
Site 6S44REVIQSDSLWLVEFY
Site 7T62CGHCQRLTPEWKKAA
Site 8S88VDADKHHSLGGQYGV
Site 9S106PTIKIFGSNKNRPED
Site 10Y114NKNRPEDYQGGRTGE
Site 11S143KDRLGGRSGGYSSGK
Site 12Y146LGGRSGGYSSGKQGR
Site 13S147GGRSGGYSSGKQGRS
Site 14S148GRSGGYSSGKQGRSD
Site 15S154SSGKQGRSDSSSKKD
Site 16S156GKQGRSDSSSKKDVI
Site 17S158QGRSDSSSKKDVIEL
Site 18T166KKDVIELTDDSFDKN
Site 19S169VIELTDDSFDKNVLD
Site 20Y186DVWMVEFYAPWCGHC
Site 21T239YGIRGFPTIKIFQKG
Site 22S248KIFQKGESPVDYDGG
Site 23Y252KGESPVDYDGGRTRS
Site 24S259YDGGRTRSDIVSRAL
Site 25S263RTRSDIVSRALDLFS
Site 26S270SRALDLFSDNAPPPE
Site 27T308VLPHILDTGAAGRNS
Site 28S315TGAAGRNSYLEVLLK
Site 29Y327LLKLADKYKKKMWGW
Site 30S375KFALLKGSFSEQGIN
Site 31S377ALLKGSFSEQGINEF
Site 32S389NEFLRELSFGRGSTA
Site 33S394ELSFGRGSTAPVGGG
Site 34T405VGGGAFPTIVEREPW
Site 35S428VEDDIDLSDVELDDL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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