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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DLGAP5
Full Name:
Disks large-associated protein 5
Alias:
discs, large-associated protein 5; disks large-associated protein DLG7; DLG1; DLG7; hepatoma up-regulated protein; HURP; KIAA0008
Type:
Microtubule binding protein; Cell cycle regulation
Mass (Da):
95115
Number AA:
846
UniProt ID:
Q15398
International Prot ID:
IPI00647892
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0031616
Uniprot
OncoNet
Molecular Function:
GO:0004721
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0007267
GO:0007079
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
S
S
H
F
A
S
R
H
R
K
D
I
S
Site 2
S15
S
R
H
R
K
D
I
S
T
E
M
I
R
T
K
Site 3
T16
R
H
R
K
D
I
S
T
E
M
I
R
T
K
I
Site 4
S28
T
K
I
A
H
R
K
S
L
S
Q
K
E
N
R
Site 5
S30
I
A
H
R
K
S
L
S
Q
K
E
N
R
H
K
Site 6
Y39
K
E
N
R
H
K
E
Y
E
R
N
R
H
F
G
Site 7
S67
L
V
E
L
D
E
T
S
Q
G
L
V
P
E
K
Site 8
T75
Q
G
L
V
P
E
K
T
N
V
K
P
R
A
M
Site 9
T84
V
K
P
R
A
M
K
T
I
L
G
D
Q
R
K
Site 10
Y97
R
K
Q
M
L
Q
K
Y
K
E
E
K
Q
L
Q
Site 11
Y123
G
I
F
K
V
G
R
Y
R
P
D
M
P
C
F
Site 12
S148
E
P
K
K
A
I
P
S
S
V
R
I
T
R
S
Site 13
S149
P
K
K
A
I
P
S
S
V
R
I
T
R
S
K
Site 14
T153
I
P
S
S
V
R
I
T
R
S
K
A
K
D
Q
Site 15
S170
Q
T
K
I
D
N
E
S
D
V
R
A
I
R
P
Site 16
T182
I
R
P
G
P
R
Q
T
S
E
K
K
V
S
D
Site 17
S183
R
P
G
P
R
Q
T
S
E
K
K
V
S
D
K
Site 18
S188
Q
T
S
E
K
K
V
S
D
K
E
K
K
V
V
Site 19
T201
V
V
Q
P
V
M
P
T
S
L
R
M
T
R
S
Site 20
S202
V
Q
P
V
M
P
T
S
L
R
M
T
R
S
A
Site 21
T206
M
P
T
S
L
R
M
T
R
S
A
T
Q
A
A
Site 22
S208
T
S
L
R
M
T
R
S
A
T
Q
A
A
K
Q
Site 23
T210
L
R
M
T
R
S
A
T
Q
A
A
K
Q
V
P
Site 24
T219
A
A
K
Q
V
P
R
T
V
S
S
T
T
A
R
Site 25
S221
K
Q
V
P
R
T
V
S
S
T
T
A
R
K
P
Site 26
T223
V
P
R
T
V
S
S
T
T
A
R
K
P
V
T
Site 27
T224
P
R
T
V
S
S
T
T
A
R
K
P
V
T
R
Site 28
S261
T
K
P
D
K
G
I
S
C
K
V
D
S
E
E
Site 29
S266
G
I
S
C
K
V
D
S
E
E
N
T
L
N
S
Site 30
T270
K
V
D
S
E
E
N
T
L
N
S
Q
T
N
A
Site 31
S273
S
E
E
N
T
L
N
S
Q
T
N
A
T
S
G
Site 32
S288
M
N
P
D
G
V
L
S
K
M
E
N
L
P
E
Site 33
S306
A
K
I
K
G
K
N
S
F
A
P
K
D
F
M
Site 34
T322
Q
P
L
D
G
L
K
T
Y
Q
V
T
P
M
T
Site 35
Y323
P
L
D
G
L
K
T
Y
Q
V
T
P
M
T
P
Site 36
T326
G
L
K
T
Y
Q
V
T
P
M
T
P
R
S
A
Site 37
T329
T
Y
Q
V
T
P
M
T
P
R
S
A
N
A
F
Site 38
S332
V
T
P
M
T
P
R
S
A
N
A
F
L
T
P
Site 39
T338
R
S
A
N
A
F
L
T
P
S
Y
T
W
T
P
Site 40
S340
A
N
A
F
L
T
P
S
Y
T
W
T
P
L
K
Site 41
T342
A
F
L
T
P
S
Y
T
W
T
P
L
K
T
E
Site 42
T344
L
T
P
S
Y
T
W
T
P
L
K
T
E
V
D
Site 43
T348
Y
T
W
T
P
L
K
T
E
V
D
E
S
Q
A
Site 44
S353
L
K
T
E
V
D
E
S
Q
A
T
K
E
I
L
Site 45
T356
E
V
D
E
S
Q
A
T
K
E
I
L
A
Q
K
Site 46
T366
I
L
A
Q
K
C
K
T
Y
S
T
K
T
I
Q
Site 47
S368
A
Q
K
C
K
T
Y
S
T
K
T
I
Q
Q
D
Site 48
S376
T
K
T
I
Q
Q
D
S
N
K
L
P
C
P
L
Site 49
T387
P
C
P
L
G
P
L
T
V
W
H
E
E
H
V
Site 50
T401
V
L
N
K
N
E
A
T
T
K
N
L
N
G
L
Site 51
T402
L
N
K
N
E
A
T
T
K
N
L
N
G
L
P
Site 52
S415
L
P
I
K
E
V
P
S
L
E
R
N
E
G
R
Site 53
Y432
Q
P
H
H
G
V
P
Y
F
R
N
I
L
Q
S
Site 54
S439
Y
F
R
N
I
L
Q
S
E
T
E
K
L
T
S
Site 55
T441
R
N
I
L
Q
S
E
T
E
K
L
T
S
H
C
Site 56
S446
S
E
T
E
K
L
T
S
H
C
F
E
W
D
R
Site 57
T469
D
A
K
D
L
I
R
T
A
V
G
Q
T
R
L
Site 58
Y494
G
L
V
D
D
C
E
Y
K
R
G
I
K
E
T
Site 59
T501
Y
K
R
G
I
K
E
T
T
C
T
D
L
D
G
Site 60
S556
V
F
R
K
K
V
V
S
G
I
A
S
K
P
K
Site 61
S560
K
V
V
S
G
I
A
S
K
P
K
Q
D
D
A
Site 62
T595
R
Q
E
E
C
A
E
T
A
V
S
V
I
P
K
Site 63
S618
A
G
F
F
R
V
E
S
P
V
K
L
F
S
G
Site 64
S624
E
S
P
V
K
L
F
S
G
L
S
V
S
S
E
Site 65
S627
V
K
L
F
S
G
L
S
V
S
S
E
G
P
S
Site 66
S629
L
F
S
G
L
S
V
S
S
E
G
P
S
Q
R
Site 67
S630
F
S
G
L
S
V
S
S
E
G
P
S
Q
R
L
Site 68
S634
S
V
S
S
E
G
P
S
Q
R
L
G
T
P
K
Site 69
T639
G
P
S
Q
R
L
G
T
P
K
S
V
N
K
A
Site 70
S642
Q
R
L
G
T
P
K
S
V
N
K
A
V
S
Q
Site 71
S648
K
S
V
N
K
A
V
S
Q
S
R
N
E
M
G
Site 72
S662
G
I
P
Q
Q
T
T
S
P
E
N
A
G
P
Q
Site 73
S673
A
G
P
Q
N
T
K
S
E
H
V
K
K
T
L
Site 74
T679
K
S
E
H
V
K
K
T
L
F
L
S
I
P
E
Site 75
S683
V
K
K
T
L
F
L
S
I
P
E
S
R
S
S
Site 76
S687
L
F
L
S
I
P
E
S
R
S
S
I
E
D
A
Site 77
S689
L
S
I
P
E
S
R
S
S
I
E
D
A
Q
C
Site 78
S690
S
I
P
E
S
R
S
S
I
E
D
A
Q
C
P
Site 79
S720
D
L
K
V
D
C
L
S
S
E
R
M
S
L
P
Site 80
S725
C
L
S
S
E
R
M
S
L
P
L
L
A
G
G
Site 81
T739
G
V
A
D
D
I
N
T
N
K
K
E
G
I
S
Site 82
S746
T
N
K
K
E
G
I
S
D
V
V
E
G
M
E
Site 83
S757
E
G
M
E
L
N
S
S
I
T
S
Q
D
V
L
Site 84
T759
M
E
L
N
S
S
I
T
S
Q
D
V
L
M
S
Site 85
S760
E
L
N
S
S
I
T
S
Q
D
V
L
M
S
S
Site 86
S767
S
Q
D
V
L
M
S
S
P
E
K
N
T
A
S
Site 87
S774
S
P
E
K
N
T
A
S
Q
N
S
I
L
E
E
Site 88
S777
K
N
T
A
S
Q
N
S
I
L
E
E
G
E
T
Site 89
T784
S
I
L
E
E
G
E
T
K
I
S
Q
S
E
L
Site 90
S787
E
E
G
E
T
K
I
S
Q
S
E
L
F
D
N
Site 91
S789
G
E
T
K
I
S
Q
S
E
L
F
D
N
K
S
Site 92
S796
S
E
L
F
D
N
K
S
L
T
T
E
C
H
L
Site 93
T798
L
F
D
N
K
S
L
T
T
E
C
H
L
L
D
Site 94
T799
F
D
N
K
S
L
T
T
E
C
H
L
L
D
S
Site 95
S806
T
E
C
H
L
L
D
S
P
G
L
N
C
S
N
Site 96
S812
D
S
P
G
L
N
C
S
N
P
F
T
Q
L
E
Site 97
T816
L
N
C
S
N
P
F
T
Q
L
E
R
R
H
Q
Site 98
S830
Q
E
H
A
R
H
I
S
F
G
G
N
L
I
T
Site 99
T837
S
F
G
G
N
L
I
T
F
S
P
L
Q
P
G
Site 100
S839
G
G
N
L
I
T
F
S
P
L
Q
P
G
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation