KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FAM133B
Full Name:
Protein FAM133B
Alias:
F133B; Family with sequence similarity 133, member B; MGC40405
Type:
Mass (Da):
28385
Number AA:
247
UniProt ID:
Q5BKY9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
K
R
D
N
R
V
A
Y
M
N
P
I
A
M
A
Site 2
S19
N
P
I
A
M
A
R
S
R
G
P
I
Q
S
S
Site 3
S25
R
S
R
G
P
I
Q
S
S
G
P
T
I
Q
D
Site 4
S26
S
R
G
P
I
Q
S
S
G
P
T
I
Q
D
Y
Site 5
T29
P
I
Q
S
S
G
P
T
I
Q
D
Y
L
N
R
Site 6
Y33
S
G
P
T
I
Q
D
Y
L
N
R
P
R
P
T
Site 7
T40
Y
L
N
R
P
R
P
T
W
E
E
V
K
E
Q
Site 8
S82
K
H
R
E
K
L
L
S
G
S
E
S
S
S
K
Site 9
S84
R
E
K
L
L
S
G
S
E
S
S
S
K
K
R
Site 10
S86
K
L
L
S
G
S
E
S
S
S
K
K
R
Q
R
Site 11
S87
L
L
S
G
S
E
S
S
S
K
K
R
Q
R
K
Site 12
S88
L
S
G
S
E
S
S
S
K
K
R
Q
R
K
K
Site 13
S101
K
K
K
E
K
K
K
S
G
R
Y
S
S
S
S
Site 14
Y104
E
K
K
K
S
G
R
Y
S
S
S
S
S
S
S
Site 15
S105
K
K
K
S
G
R
Y
S
S
S
S
S
S
S
S
Site 16
S106
K
K
S
G
R
Y
S
S
S
S
S
S
S
S
D
Site 17
S107
K
S
G
R
Y
S
S
S
S
S
S
S
S
D
S
Site 18
S108
S
G
R
Y
S
S
S
S
S
S
S
S
D
S
S
Site 19
S109
G
R
Y
S
S
S
S
S
S
S
S
D
S
S
S
Site 20
S110
R
Y
S
S
S
S
S
S
S
S
D
S
S
S
S
Site 21
S111
Y
S
S
S
S
S
S
S
S
D
S
S
S
S
S
Site 22
S112
S
S
S
S
S
S
S
S
D
S
S
S
S
S
S
Site 23
S114
S
S
S
S
S
S
D
S
S
S
S
S
S
D
S
Site 24
S115
S
S
S
S
S
D
S
S
S
S
S
S
D
S
E
Site 25
S116
S
S
S
S
D
S
S
S
S
S
S
D
S
E
D
Site 26
S117
S
S
S
D
S
S
S
S
S
S
D
S
E
D
E
Site 27
S118
S
S
D
S
S
S
S
S
S
D
S
E
D
E
D
Site 28
S119
S
D
S
S
S
S
S
S
D
S
E
D
E
D
K
Site 29
S121
S
S
S
S
S
S
D
S
E
D
E
D
K
K
Q
Site 30
S139
R
K
K
K
K
N
R
S
H
K
S
S
E
S
S
Site 31
S142
K
K
N
R
S
H
K
S
S
E
S
S
M
S
E
Site 32
S143
K
N
R
S
H
K
S
S
E
S
S
M
S
E
T
Site 33
S145
R
S
H
K
S
S
E
S
S
M
S
E
T
E
S
Site 34
S146
S
H
K
S
S
E
S
S
M
S
E
T
E
S
D
Site 35
S148
K
S
S
E
S
S
M
S
E
T
E
S
D
S
K
Site 36
T150
S
E
S
S
M
S
E
T
E
S
D
S
K
D
S
Site 37
S152
S
S
M
S
E
T
E
S
D
S
K
D
S
L
K
Site 38
S154
M
S
E
T
E
S
D
S
K
D
S
L
K
K
K
Site 39
S157
T
E
S
D
S
K
D
S
L
K
K
K
K
K
S
Site 40
S164
S
L
K
K
K
K
K
S
K
D
G
T
E
K
E
Site 41
T168
K
K
K
S
K
D
G
T
E
K
E
K
D
I
K
Site 42
S178
E
K
D
I
K
G
L
S
K
K
R
K
M
Y
S
Site 43
Y184
L
S
K
K
R
K
M
Y
S
E
D
K
P
L
S
Site 44
S185
S
K
K
R
K
M
Y
S
E
D
K
P
L
S
S
Site 45
S191
Y
S
E
D
K
P
L
S
S
E
S
L
S
E
S
Site 46
S192
S
E
D
K
P
L
S
S
E
S
L
S
E
S
E
Site 47
S194
D
K
P
L
S
S
E
S
L
S
E
S
E
Y
I
Site 48
S196
P
L
S
S
E
S
L
S
E
S
E
Y
I
E
E
Site 49
S198
S
S
E
S
L
S
E
S
E
Y
I
E
E
V
R
Site 50
Y200
E
S
L
S
E
S
E
Y
I
E
E
V
R
A
K
Site 51
S211
V
R
A
K
K
K
K
S
S
E
E
R
E
K
A
Site 52
S212
R
A
K
K
K
K
S
S
E
E
R
E
K
A
T
Site 53
S241
K
K
K
K
K
A
A
S
S
S
P
D
S
P
_
Site 54
S242
K
K
K
K
A
A
S
S
S
P
D
S
P
_
_
Site 55
S243
K
K
K
A
A
S
S
S
P
D
S
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation