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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYT6
Full Name:
Synaptotagmin-6
Alias:
Synaptotagmin VI; SytVI
Type:
Vesicle protein
Mass (Da):
57383
Number AA:
510
UniProt ID:
Q5T7P8
International Prot ID:
IPI00180851
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0016021
GO:0008021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Synaptotagmin-6 pan-specific antibody AB-NN367-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN367-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T36
P
L
G
L
D
V
E
T
C
R
S
F
E
L
Q
Site 2
S39
L
D
V
E
T
C
R
S
F
E
L
Q
P
P
E
Site 3
S48
E
L
Q
P
P
E
R
S
P
S
A
A
G
A
G
Site 4
S50
Q
P
P
E
R
S
P
S
A
A
G
A
G
T
S
Site 5
S94
P
W
R
N
K
E
A
S
S
P
S
S
A
N
P
Site 6
S95
W
R
N
K
E
A
S
S
P
S
S
A
N
P
P
Site 7
S98
K
E
A
S
S
P
S
S
A
N
P
P
L
E
A
Site 8
S108
P
P
L
E
A
L
Q
S
P
S
F
R
G
N
M
Site 9
S110
L
E
A
L
Q
S
P
S
F
R
G
N
M
A
D
Site 10
T124
D
K
L
K
D
P
S
T
L
G
F
L
E
A
A
Site 11
S138
A
V
K
I
S
H
T
S
P
D
I
P
A
E
V
Site 12
S148
I
P
A
E
V
Q
M
S
V
K
E
H
I
M
R
Site 13
T157
K
E
H
I
M
R
H
T
R
L
Q
R
Q
T
T
Site 14
T163
H
T
R
L
Q
R
Q
T
T
E
P
A
S
S
T
Site 15
T164
T
R
L
Q
R
Q
T
T
E
P
A
S
S
T
R
Site 16
S168
R
Q
T
T
E
P
A
S
S
T
R
H
T
S
F
Site 17
S169
Q
T
T
E
P
A
S
S
T
R
H
T
S
F
K
Site 18
T173
P
A
S
S
T
R
H
T
S
F
K
R
H
L
P
Site 19
S174
A
S
S
T
R
H
T
S
F
K
R
H
L
P
R
Site 20
S186
L
P
R
Q
M
H
V
S
S
V
D
Y
G
N
E
Site 21
S187
P
R
Q
M
H
V
S
S
V
D
Y
G
N
E
L
Site 22
Y190
M
H
V
S
S
V
D
Y
G
N
E
L
P
P
A
Site 23
S203
P
A
A
E
Q
P
T
S
I
G
R
I
K
P
E
Site 24
Y212
G
R
I
K
P
E
L
Y
K
Q
K
S
V
D
G
Site 25
S216
P
E
L
Y
K
Q
K
S
V
D
G
E
D
A
K
Site 26
S224
V
D
G
E
D
A
K
S
E
A
T
K
S
C
G
Site 27
S229
A
K
S
E
A
T
K
S
C
G
K
I
N
F
S
Site 28
S236
S
C
G
K
I
N
F
S
L
R
Y
D
Y
E
T
Site 29
Y241
N
F
S
L
R
Y
D
Y
E
T
E
T
L
I
V
Site 30
T243
S
L
R
Y
D
Y
E
T
E
T
L
I
V
R
I
Site 31
T245
R
Y
D
Y
E
T
E
T
L
I
V
R
I
L
K
Site 32
S265
A
K
D
F
C
G
S
S
D
P
Y
V
K
I
Y
Site 33
Y272
S
D
P
Y
V
K
I
Y
L
L
P
D
R
K
C
Site 34
T283
D
R
K
C
K
L
Q
T
R
V
H
R
K
T
L
Site 35
T289
Q
T
R
V
H
R
K
T
L
N
P
T
F
D
E
Site 36
T293
H
R
K
T
L
N
P
T
F
D
E
N
F
H
F
Site 37
S315
A
D
R
K
L
H
L
S
V
F
D
F
D
R
F
Site 38
S340
L
D
N
L
F
E
A
S
D
L
S
R
E
T
S
Site 39
S343
L
F
E
A
S
D
L
S
R
E
T
S
I
W
K
Site 40
T346
A
S
D
L
S
R
E
T
S
I
W
K
D
I
Q
Site 41
S347
S
D
L
S
R
E
T
S
I
W
K
D
I
Q
Y
Site 42
Y354
S
I
W
K
D
I
Q
Y
A
T
S
E
S
V
D
Site 43
T394
N
L
K
A
M
D
I
T
G
Y
S
D
P
Y
V
Site 44
Y396
K
A
M
D
I
T
G
Y
S
D
P
Y
V
K
V
Site 45
S397
A
M
D
I
T
G
Y
S
D
P
Y
V
K
V
S
Site 46
T417
R
R
L
K
K
K
K
T
T
I
K
K
N
T
L
Site 47
T418
R
L
K
K
K
K
T
T
I
K
K
N
T
L
N
Site 48
T423
K
T
T
I
K
K
N
T
L
N
P
V
Y
N
E
Site 49
Y428
K
N
T
L
N
P
V
Y
N
E
A
I
I
F
D
Site 50
Y453
L
L
I
S
V
M
D
Y
D
R
V
G
H
N
E
Site 51
S495
K
P
I
A
H
W
H
S
L
V
E
V
K
K
S
Site 52
S502
S
L
V
E
V
K
K
S
F
K
E
G
N
P
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation