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Updated November 2019
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Protein Info
Short Name:
MAST2
Full Name:
Microtubule-associated serine/threonine-protein kinase 2
Alias:
EC 2.7.11.1; KIAA0807; MAST205; Microtubule associated serine/threonine kinase 2
Type:
EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor);
AGC
group; MAST family
Mass (Da):
196436
Number AA:
1798
UniProt ID:
Q6P0Q8
International Prot ID:
IPI00480046
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0019902
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
GO:0045075
GO:0048515
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
V
Q
R
A
A
E
L
S
Q
S
L
P
P
R
R
Site 2
S31
R
A
A
E
L
S
Q
S
L
P
P
R
R
R
A
Site 3
T49
R
Q
R
L
E
E
R
T
G
P
A
G
P
E
G
Site 4
S66
Q
D
V
V
T
G
V
S
P
L
L
F
R
K
L
Site 5
S74
P
L
L
F
R
K
L
S
N
P
D
I
F
S
S
Site 6
S80
L
S
N
P
D
I
F
S
S
T
G
K
V
K
L
Site 7
S81
S
N
P
D
I
F
S
S
T
G
K
V
K
L
Q
Site 8
T82
N
P
D
I
F
S
S
T
G
K
V
K
L
Q
R
Site 9
S92
V
K
L
Q
R
Q
L
S
Q
D
D
C
K
L
W
Site 10
S105
L
W
R
G
N
L
A
S
S
L
S
G
K
Q
L
Site 11
S106
W
R
G
N
L
A
S
S
L
S
G
K
Q
L
L
Site 12
S116
G
K
Q
L
L
P
L
S
S
S
V
H
S
S
V
Site 13
S117
K
Q
L
L
P
L
S
S
S
V
H
S
S
V
G
Site 14
S118
Q
L
L
P
L
S
S
S
V
H
S
S
V
G
Q
Site 15
S121
P
L
S
S
S
V
H
S
S
V
G
Q
V
T
W
Site 16
S122
L
S
S
S
V
H
S
S
V
G
Q
V
T
W
Q
Site 17
T127
H
S
S
V
G
Q
V
T
W
Q
S
S
G
E
A
Site 18
S130
V
G
Q
V
T
W
Q
S
S
G
E
A
S
N
L
Site 19
S131
G
Q
V
T
W
Q
S
S
G
E
A
S
N
L
V
Site 20
S135
W
Q
S
S
G
E
A
S
N
L
V
R
M
R
N
Site 21
S144
L
V
R
M
R
N
Q
S
L
G
Q
S
A
P
S
Site 22
S148
R
N
Q
S
L
G
Q
S
A
P
S
L
T
A
G
Site 23
S151
S
L
G
Q
S
A
P
S
L
T
A
G
L
K
E
Site 24
S160
T
A
G
L
K
E
L
S
L
P
R
R
G
S
F
Site 25
S166
L
S
L
P
R
R
G
S
F
C
R
T
S
N
R
Site 26
T170
R
R
G
S
F
C
R
T
S
N
R
K
S
L
I
Site 27
S171
R
G
S
F
C
R
T
S
N
R
K
S
L
I
V
Site 28
S175
C
R
T
S
N
R
K
S
L
I
V
T
S
S
T
Site 29
T179
N
R
K
S
L
I
V
T
S
S
T
S
P
T
L
Site 30
S180
R
K
S
L
I
V
T
S
S
T
S
P
T
L
P
Site 31
S181
K
S
L
I
V
T
S
S
T
S
P
T
L
P
R
Site 32
S183
L
I
V
T
S
S
T
S
P
T
L
P
R
P
H
Site 33
T185
V
T
S
S
T
S
P
T
L
P
R
P
H
S
P
Site 34
S191
P
T
L
P
R
P
H
S
P
L
H
G
H
T
G
Site 35
S200
L
H
G
H
T
G
N
S
P
L
D
S
P
R
N
Site 36
S204
T
G
N
S
P
L
D
S
P
R
N
F
S
P
N
Site 37
S209
L
D
S
P
R
N
F
S
P
N
A
P
A
H
F
Site 38
S217
P
N
A
P
A
H
F
S
F
V
P
A
R
R
T
Site 39
T224
S
F
V
P
A
R
R
T
D
G
R
R
W
S
L
Site 40
S230
R
T
D
G
R
R
W
S
L
A
S
L
P
S
S
Site 41
S233
G
R
R
W
S
L
A
S
L
P
S
S
G
Y
G
Site 42
S237
S
L
A
S
L
P
S
S
G
Y
G
T
N
T
P
Site 43
Y239
A
S
L
P
S
S
G
Y
G
T
N
T
P
S
S
Site 44
T241
L
P
S
S
G
Y
G
T
N
T
P
S
S
T
V
Site 45
T243
S
S
G
Y
G
T
N
T
P
S
S
T
V
S
S
Site 46
S245
G
Y
G
T
N
T
P
S
S
T
V
S
S
S
C
Site 47
S246
Y
G
T
N
T
P
S
S
T
V
S
S
S
C
S
Site 48
T247
G
T
N
T
P
S
S
T
V
S
S
S
C
S
S
Site 49
S249
N
T
P
S
S
T
V
S
S
S
C
S
S
Q
E
Site 50
S250
T
P
S
S
T
V
S
S
S
C
S
S
Q
E
K
Site 51
S251
P
S
S
T
V
S
S
S
C
S
S
Q
E
K
L
Site 52
S253
S
T
V
S
S
S
C
S
S
Q
E
K
L
H
Q
Site 53
S254
T
V
S
S
S
C
S
S
Q
E
K
L
H
Q
L
Site 54
T274
A
D
E
L
H
F
L
T
K
H
F
S
T
E
S
Site 55
S278
H
F
L
T
K
H
F
S
T
E
S
V
P
D
E
Site 56
T279
F
L
T
K
H
F
S
T
E
S
V
P
D
E
E
Site 57
S281
T
K
H
F
S
T
E
S
V
P
D
E
E
G
R
Site 58
S290
P
D
E
E
G
R
Q
S
P
A
M
R
P
R
S
Site 59
S297
S
P
A
M
R
P
R
S
R
S
L
S
P
G
R
Site 60
S299
A
M
R
P
R
S
R
S
L
S
P
G
R
S
P
Site 61
S301
R
P
R
S
R
S
L
S
P
G
R
S
P
V
S
Site 62
S305
R
S
L
S
P
G
R
S
P
V
S
F
D
S
E
Site 63
S308
S
P
G
R
S
P
V
S
F
D
S
E
I
I
M
Site 64
S311
R
S
P
V
S
F
D
S
E
I
I
M
M
N
H
Site 65
Y320
I
I
M
M
N
H
V
Y
K
E
R
F
P
K
A
Site 66
S340
E
R
L
A
E
F
I
S
S
N
T
P
D
S
V
Site 67
S341
R
L
A
E
F
I
S
S
N
T
P
D
S
V
L
Site 68
S346
I
S
S
N
T
P
D
S
V
L
P
L
A
D
G
Site 69
S373
A
R
D
C
L
D
K
S
R
S
G
L
I
T
S
Site 70
S375
D
C
L
D
K
S
R
S
G
L
I
T
S
Q
Y
Site 71
T379
K
S
R
S
G
L
I
T
S
Q
Y
F
Y
E
L
Site 72
S380
S
R
S
G
L
I
T
S
Q
Y
F
Y
E
L
Q
Site 73
Y382
S
G
L
I
T
S
Q
Y
F
Y
E
L
Q
D
N
Site 74
Y384
L
I
T
S
Q
Y
F
Y
E
L
Q
D
N
L
E
Site 75
S403
D
A
H
E
R
S
E
S
S
E
V
A
F
V
M
Site 76
Y461
I
K
C
D
I
P
R
Y
I
V
S
Q
L
G
L
Site 77
S464
D
I
P
R
Y
I
V
S
Q
L
G
L
T
R
D
Site 78
S480
L
E
E
M
A
Q
L
S
S
C
D
S
P
D
T
Site 79
S481
E
E
M
A
Q
L
S
S
C
D
S
P
D
T
P
Site 80
S484
A
Q
L
S
S
C
D
S
P
D
T
P
E
T
D
Site 81
T487
S
S
C
D
S
P
D
T
P
E
T
D
D
S
I
Site 82
T490
D
S
P
D
T
P
E
T
D
D
S
I
E
G
H
Site 83
S493
D
T
P
E
T
D
D
S
I
E
G
H
G
A
S
Site 84
S500
S
I
E
G
H
G
A
S
L
P
S
K
K
T
P
Site 85
T506
A
S
L
P
S
K
K
T
P
S
E
E
D
F
E
Site 86
S508
L
P
S
K
K
T
P
S
E
E
D
F
E
T
I
Site 87
T514
P
S
E
E
D
F
E
T
I
K
L
I
S
N
G
Site 88
S533
V
F
L
V
R
H
K
S
T
R
Q
R
F
A
M
Site 89
Y625
E
T
V
L
A
L
E
Y
L
H
N
Y
G
I
V
Site 90
Y629
A
L
E
Y
L
H
N
Y
G
I
V
H
R
D
L
Site 91
T665
K
I
G
L
M
S
L
T
T
N
L
Y
E
G
H
Site 92
Y669
M
S
L
T
T
N
L
Y
E
G
H
I
E
K
D
Site 93
T688
L
D
K
Q
V
C
G
T
P
E
Y
I
A
P
E
Site 94
Y702
E
V
I
L
R
Q
G
Y
G
K
P
V
D
W
W
Site 95
T729
C
V
P
F
F
G
D
T
P
E
E
L
F
G
Q
Site 96
T759
P
P
D
A
Q
D
L
T
S
K
L
L
H
Q
N
Site 97
S760
P
D
A
Q
D
L
T
S
K
L
L
H
Q
N
P
Site 98
T773
N
P
L
E
R
L
G
T
G
S
A
Y
E
V
K
Site 99
S775
L
E
R
L
G
T
G
S
A
Y
E
V
K
Q
H
Site 100
Y777
R
L
G
T
G
S
A
Y
E
V
K
Q
H
P
F
Site 101
S806
E
F
I
P
Q
L
E
S
E
D
D
T
S
Y
F
Site 102
T810
Q
L
E
S
E
D
D
T
S
Y
F
D
T
R
S
Site 103
S811
L
E
S
E
D
D
T
S
Y
F
D
T
R
S
E
Site 104
Y812
E
S
E
D
D
T
S
Y
F
D
T
R
S
E
R
Site 105
T815
D
D
T
S
Y
F
D
T
R
S
E
R
Y
H
H
Site 106
S825
E
R
Y
H
H
M
D
S
E
D
E
E
E
V
S
Site 107
S832
S
E
D
E
E
E
V
S
E
D
G
C
L
E
I
Site 108
S843
C
L
E
I
R
Q
F
S
S
C
S
P
R
F
N
Site 109
S846
I
R
Q
F
S
S
C
S
P
R
F
N
K
V
Y
Site 110
Y853
S
P
R
F
N
K
V
Y
S
S
M
E
R
L
S
Site 111
S854
P
R
F
N
K
V
Y
S
S
M
E
R
L
S
L
Site 112
S855
R
F
N
K
V
Y
S
S
M
E
R
L
S
L
L
Site 113
S860
Y
S
S
M
E
R
L
S
L
L
E
E
R
R
T
Site 114
T867
S
L
L
E
E
R
R
T
P
P
P
T
K
R
S
Site 115
T871
E
R
R
T
P
P
P
T
K
R
S
L
S
E
E
Site 116
S874
T
P
P
P
T
K
R
S
L
S
E
E
K
E
D
Site 117
S876
P
P
T
K
R
S
L
S
E
E
K
E
D
H
S
Site 118
S883
S
E
E
K
E
D
H
S
D
G
L
A
G
L
K
Site 119
S895
G
L
K
G
R
D
R
S
W
V
I
G
S
P
E
Site 120
S900
D
R
S
W
V
I
G
S
P
E
I
L
R
K
R
Site 121
S909
E
I
L
R
K
R
L
S
V
S
E
S
S
H
T
Site 122
S911
L
R
K
R
L
S
V
S
E
S
S
H
T
E
S
Site 123
S913
K
R
L
S
V
S
E
S
S
H
T
E
S
D
S
Site 124
S914
R
L
S
V
S
E
S
S
H
T
E
S
D
S
S
Site 125
T916
S
V
S
E
S
S
H
T
E
S
D
S
S
P
P
Site 126
S918
S
E
S
S
H
T
E
S
D
S
S
P
P
M
T
Site 127
S920
S
S
H
T
E
S
D
S
S
P
P
M
T
V
R
Site 128
S921
S
H
T
E
S
D
S
S
P
P
M
T
V
R
R
Site 129
T925
S
D
S
S
P
P
M
T
V
R
R
R
C
S
G
Site 130
S931
M
T
V
R
R
R
C
S
G
L
L
D
A
P
R
Site 131
S948
E
G
P
E
E
A
S
S
T
L
R
R
Q
P
Q
Site 132
T949
G
P
E
E
A
S
S
T
L
R
R
Q
P
Q
E
Site 133
T962
Q
E
G
I
W
V
L
T
P
P
S
G
E
G
V
Site 134
S970
P
P
S
G
E
G
V
S
G
P
V
T
E
H
S
Site 135
T974
E
G
V
S
G
P
V
T
E
H
S
G
E
Q
R
Site 136
S992
D
E
E
A
V
G
R
S
S
G
S
S
P
A
M
Site 137
S993
E
E
A
V
G
R
S
S
G
S
S
P
A
M
E
Site 138
S995
A
V
G
R
S
S
G
S
S
P
A
M
E
T
R
Site 139
S996
V
G
R
S
S
G
S
S
P
A
M
E
T
R
G
Site 140
T1006
M
E
T
R
G
R
G
T
S
Q
L
A
E
G
A
Site 141
S1007
E
T
R
G
R
G
T
S
Q
L
A
E
G
A
T
Site 142
S1032
R
A
R
H
R
L
L
S
G
D
S
T
E
K
R
Site 143
S1035
H
R
L
L
S
G
D
S
T
E
K
R
T
A
R
Site 144
T1036
R
L
L
S
G
D
S
T
E
K
R
T
A
R
P
Site 145
T1066
L
I
P
S
E
H
H
T
C
S
P
L
A
S
P
Site 146
S1068
P
S
E
H
H
T
C
S
P
L
A
S
P
M
S
Site 147
S1072
H
T
C
S
P
L
A
S
P
M
S
P
H
S
Q
Site 148
S1075
S
P
L
A
S
P
M
S
P
H
S
Q
S
S
N
Site 149
S1078
A
S
P
M
S
P
H
S
Q
S
S
N
P
S
S
Site 150
S1080
P
M
S
P
H
S
Q
S
S
N
P
S
S
R
D
Site 151
S1081
M
S
P
H
S
Q
S
S
N
P
S
S
R
D
S
Site 152
S1084
H
S
Q
S
S
N
P
S
S
R
D
S
S
P
S
Site 153
S1085
S
Q
S
S
N
P
S
S
R
D
S
S
P
S
R
Site 154
S1088
S
N
P
S
S
R
D
S
S
P
S
R
D
F
L
Site 155
S1089
N
P
S
S
R
D
S
S
P
S
R
D
F
L
P
Site 156
S1091
S
S
R
D
S
S
P
S
R
D
F
L
P
A
L
Site 157
Y1114
I
H
R
A
G
K
K
Y
G
F
T
L
R
A
I
Site 158
T1117
A
G
K
K
Y
G
F
T
L
R
A
I
R
V
Y
Site 159
Y1124
T
L
R
A
I
R
V
Y
M
G
D
S
D
V
Y
Site 160
S1147
V
E
D
G
G
P
A
S
E
A
G
L
R
Q
G
Site 161
T1158
L
R
Q
G
D
L
I
T
H
V
N
G
E
P
V
Site 162
S1187
S
G
N
K
V
A
I
S
T
T
P
L
E
N
T
Site 163
T1189
N
K
V
A
I
S
T
T
P
L
E
N
T
S
I
Site 164
S1205
V
G
P
A
R
K
G
S
Y
K
A
K
M
A
R
Site 165
S1214
K
A
K
M
A
R
R
S
K
R
S
R
G
K
D
Site 166
S1217
M
A
R
R
S
K
R
S
R
G
K
D
G
Q
E
Site 167
S1225
R
G
K
D
G
Q
E
S
R
K
R
S
S
L
F
Site 168
S1229
G
Q
E
S
R
K
R
S
S
L
F
R
K
I
T
Site 169
S1230
Q
E
S
R
K
R
S
S
L
F
R
K
I
T
K
Site 170
T1236
S
S
L
F
R
K
I
T
K
Q
A
S
L
L
H
Site 171
S1240
R
K
I
T
K
Q
A
S
L
L
H
T
S
R
S
Site 172
T1244
K
Q
A
S
L
L
H
T
S
R
S
L
S
S
L
Site 173
S1245
Q
A
S
L
L
H
T
S
R
S
L
S
S
L
N
Site 174
S1247
S
L
L
H
T
S
R
S
L
S
S
L
N
R
S
Site 175
S1249
L
H
T
S
R
S
L
S
S
L
N
R
S
L
S
Site 176
S1250
H
T
S
R
S
L
S
S
L
N
R
S
L
S
S
Site 177
S1254
S
L
S
S
L
N
R
S
L
S
S
G
E
S
G
Site 178
S1256
S
S
L
N
R
S
L
S
S
G
E
S
G
P
G
Site 179
S1257
S
L
N
R
S
L
S
S
G
E
S
G
P
G
S
Site 180
S1260
R
S
L
S
S
G
E
S
G
P
G
S
P
T
H
Site 181
S1264
S
G
E
S
G
P
G
S
P
T
H
S
H
S
L
Site 182
T1266
E
S
G
P
G
S
P
T
H
S
H
S
L
S
P
Site 183
S1268
G
P
G
S
P
T
H
S
H
S
L
S
P
R
S
Site 184
S1270
G
S
P
T
H
S
H
S
L
S
P
R
S
P
T
Site 185
S1272
P
T
H
S
H
S
L
S
P
R
S
P
T
Q
G
Site 186
S1275
S
H
S
L
S
P
R
S
P
T
Q
G
Y
R
V
Site 187
T1277
S
L
S
P
R
S
P
T
Q
G
Y
R
V
T
P
Site 188
T1283
P
T
Q
G
Y
R
V
T
P
D
A
V
H
S
V
Site 189
S1289
V
T
P
D
A
V
H
S
V
G
G
N
S
S
Q
Site 190
S1294
V
H
S
V
G
G
N
S
S
Q
S
S
S
P
S
Site 191
S1295
H
S
V
G
G
N
S
S
Q
S
S
S
P
S
S
Site 192
S1297
V
G
G
N
S
S
Q
S
S
S
P
S
S
S
V
Site 193
S1298
G
G
N
S
S
Q
S
S
S
P
S
S
S
V
P
Site 194
S1299
G
N
S
S
Q
S
S
S
P
S
S
S
V
P
S
Site 195
S1301
S
S
Q
S
S
S
P
S
S
S
V
P
S
S
P
Site 196
S1302
S
Q
S
S
S
P
S
S
S
V
P
S
S
P
A
Site 197
S1303
Q
S
S
S
P
S
S
S
V
P
S
S
P
A
G
Site 198
S1306
S
P
S
S
S
V
P
S
S
P
A
G
S
G
H
Site 199
S1307
P
S
S
S
V
P
S
S
P
A
G
S
G
H
T
Site 200
S1311
V
P
S
S
P
A
G
S
G
H
T
R
P
S
S
Site 201
T1314
S
P
A
G
S
G
H
T
R
P
S
S
L
H
G
Site 202
S1317
G
S
G
H
T
R
P
S
S
L
H
G
L
A
P
Site 203
S1318
S
G
H
T
R
P
S
S
L
H
G
L
A
P
K
Site 204
Y1330
A
P
K
L
Q
R
Q
Y
R
S
P
R
R
K
S
Site 205
S1332
K
L
Q
R
Q
Y
R
S
P
R
R
K
S
A
G
Site 206
S1337
Y
R
S
P
R
R
K
S
A
G
S
I
P
L
S
Site 207
S1340
P
R
R
K
S
A
G
S
I
P
L
S
P
L
A
Site 208
S1344
S
A
G
S
I
P
L
S
P
L
A
H
T
P
S
Site 209
T1349
P
L
S
P
L
A
H
T
P
S
P
P
P
P
T
Site 210
S1351
S
P
L
A
H
T
P
S
P
P
P
P
T
A
S
Site 211
T1356
T
P
S
P
P
P
P
T
A
S
P
Q
R
S
P
Site 212
S1358
S
P
P
P
P
T
A
S
P
Q
R
S
P
S
P
Site 213
S1362
P
T
A
S
P
Q
R
S
P
S
P
L
S
G
H
Site 214
S1364
A
S
P
Q
R
S
P
S
P
L
S
G
H
V
A
Site 215
S1367
Q
R
S
P
S
P
L
S
G
H
V
A
Q
A
F
Site 216
S1381
F
P
T
K
L
H
L
S
P
P
L
G
R
Q
L
Site 217
S1389
P
P
L
G
R
Q
L
S
R
P
K
S
A
E
P
Site 218
S1393
R
Q
L
S
R
P
K
S
A
E
P
P
R
S
P
Site 219
S1399
K
S
A
E
P
P
R
S
P
L
L
K
R
V
Q
Site 220
S1407
P
L
L
K
R
V
Q
S
A
E
K
L
A
A
A
Site 221
T1424
A
S
E
K
K
L
A
T
S
R
K
H
S
L
D
Site 222
S1425
S
E
K
K
L
A
T
S
R
K
H
S
L
D
L
Site 223
S1429
L
A
T
S
R
K
H
S
L
D
L
P
H
S
E
Site 224
S1435
H
S
L
D
L
P
H
S
E
L
K
K
E
L
P
Site 225
S1447
E
L
P
P
R
E
V
S
P
L
E
V
V
G
A
Site 226
S1475
G
V
L
Q
P
A
P
S
R
A
L
G
T
L
R
Site 227
T1480
A
P
S
R
A
L
G
T
L
R
Q
D
R
A
E
Site 228
S1491
D
R
A
E
R
R
E
S
L
Q
K
Q
E
A
I
Site 229
S1503
E
A
I
R
E
V
D
S
S
E
D
D
T
E
E
Site 230
S1504
A
I
R
E
V
D
S
S
E
D
D
T
E
E
G
Site 231
T1508
V
D
S
S
E
D
D
T
E
E
G
P
E
N
S
Site 232
S1522
S
Q
G
A
Q
E
L
S
L
A
P
H
P
E
V
Site 233
S1530
L
A
P
H
P
E
V
S
Q
S
V
A
P
K
G
Site 234
S1532
P
H
P
E
V
S
Q
S
V
A
P
K
G
A
G
Site 235
S1554
F
P
S
R
D
P
R
S
L
G
P
M
V
P
S
Site 236
S1575
L
G
P
P
R
M
E
S
P
S
G
P
H
R
R
Site 237
S1577
P
P
R
M
E
S
P
S
G
P
H
R
R
L
G
Site 238
S1585
G
P
H
R
R
L
G
S
P
Q
A
I
E
E
A
Site 239
S1594
Q
A
I
E
E
A
A
S
S
S
S
A
G
P
N
Site 240
S1595
A
I
E
E
A
A
S
S
S
S
A
G
P
N
L
Site 241
S1597
E
E
A
A
S
S
S
S
A
G
P
N
L
G
Q
Site 242
S1605
A
G
P
N
L
G
Q
S
G
A
T
D
P
I
P
Site 243
S1635
T
A
L
S
P
S
T
S
G
L
T
P
T
S
S
Site 244
T1638
S
P
S
T
S
G
L
T
P
T
S
S
C
S
P
Site 245
T1640
S
T
S
G
L
T
P
T
S
S
C
S
P
P
S
Site 246
S1641
T
S
G
L
T
P
T
S
S
C
S
P
P
S
S
Site 247
S1642
S
G
L
T
P
T
S
S
C
S
P
P
S
S
T
Site 248
S1644
L
T
P
T
S
S
C
S
P
P
S
S
T
S
G
Site 249
S1647
T
S
S
C
S
P
P
S
S
T
S
G
K
L
S
Site 250
S1648
S
S
C
S
P
P
S
S
T
S
G
K
L
S
M
Site 251
T1649
S
C
S
P
P
S
S
T
S
G
K
L
S
M
W
Site 252
S1650
C
S
P
P
S
S
T
S
G
K
L
S
M
W
S
Site 253
S1654
S
S
T
S
G
K
L
S
M
W
S
W
K
S
L
Site 254
S1657
S
G
K
L
S
M
W
S
W
K
S
L
I
E
G
Site 255
S1660
L
S
M
W
S
W
K
S
L
I
E
G
P
D
R
Site 256
S1669
I
E
G
P
D
R
A
S
P
S
R
K
A
T
M
Site 257
T1675
A
S
P
S
R
K
A
T
M
A
G
G
L
A
N
Site 258
T1690
L
Q
D
L
E
N
T
T
P
A
Q
P
K
N
L
Site 259
S1698
P
A
Q
P
K
N
L
S
P
R
E
Q
G
K
T
Site 260
T1705
S
P
R
E
Q
G
K
T
Q
P
P
S
A
P
R
Site 261
S1709
Q
G
K
T
Q
P
P
S
A
P
R
L
A
H
P
Site 262
S1717
A
P
R
L
A
H
P
S
Y
E
D
P
S
Q
G
Site 263
Y1718
P
R
L
A
H
P
S
Y
E
D
P
S
Q
G
W
Site 264
S1722
H
P
S
Y
E
D
P
S
Q
G
W
L
W
E
S
Site 265
S1742
V
K
E
D
P
A
L
S
I
T
Q
V
P
D
A
Site 266
T1744
E
D
P
A
L
S
I
T
Q
V
P
D
A
S
G
Site 267
T1765
P
C
R
G
C
P
L
T
Q
K
S
E
P
S
L
Site 268
S1768
G
C
P
L
T
Q
K
S
E
P
S
L
R
R
G
Site 269
S1771
L
T
Q
K
S
E
P
S
L
R
R
G
Q
E
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation