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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSSK4
Full Name:
Testis-specific serine/threonine-protein kinase 4
Alias:
EC 2.7.11.1; C14orf20; STK22E; TSK4
Type:
Protein-serine kinase, CAMK group, TSSK family
Mass (Da):
37454
Number AA:
328
UniProt ID:
Q6SA08
International Prot ID:
IPI00646936
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0032793
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
D
V
L
E
A
A
P
T
T
T
A
Y
H
S
L
Site 2
T14
L
E
A
A
P
T
T
T
A
Y
H
S
L
M
D
Site 3
Y16
A
A
P
T
T
T
A
Y
H
S
L
M
D
E
Y
Site 4
S18
P
T
T
T
A
Y
H
S
L
M
D
E
Y
G
Y
Site 5
Y23
Y
H
S
L
M
D
E
Y
G
Y
E
V
G
K
A
Site 6
Y25
S
L
M
D
E
Y
G
Y
E
V
G
K
A
I
G
Site 7
S35
G
K
A
I
G
H
G
S
Y
G
S
V
Y
E
A
Site 8
Y36
K
A
I
G
H
G
S
Y
G
S
V
Y
E
A
F
Site 9
S38
I
G
H
G
S
Y
G
S
V
Y
E
A
F
Y
T
Site 10
Y40
H
G
S
Y
G
S
V
Y
E
A
F
Y
T
K
Q
Site 11
S62
I
I
S
K
K
K
A
S
D
D
Y
L
N
K
F
Site 12
Y65
K
K
K
A
S
D
D
Y
L
N
K
F
L
P
R
Site 13
Y84
M
K
V
L
R
H
K
Y
L
I
N
F
Y
R
A
Site 14
Y117
V
L
E
W
I
Q
R
Y
G
A
C
S
E
P
L
Site 15
S121
I
Q
R
Y
G
A
C
S
E
P
L
A
G
K
W
Site 16
S143
I
A
Y
L
H
S
K
S
I
V
H
R
D
L
K
Site 17
S175
G
F
A
K
M
V
P
S
N
Q
P
V
G
C
S
Site 18
S182
S
N
Q
P
V
G
C
S
P
S
Y
R
Q
V
N
Site 19
Y185
P
V
G
C
S
P
S
Y
R
Q
V
N
C
F
S
Site 20
Y215
E
I
L
R
G
L
P
Y
N
P
F
L
S
D
T
Site 21
S220
L
P
Y
N
P
F
L
S
D
T
W
S
M
G
V
Site 22
T242
A
H
L
P
F
D
D
T
N
L
K
K
L
L
R
Site 23
T251
L
K
K
L
L
R
E
T
Q
K
E
V
T
F
P
Site 24
T256
R
E
T
Q
K
E
V
T
F
P
A
N
H
T
I
Site 25
S264
F
P
A
N
H
T
I
S
Q
E
C
K
N
L
I
Site 26
T279
L
Q
M
L
R
Q
A
T
K
R
A
T
I
L
D
Site 27
T283
R
Q
A
T
K
R
A
T
I
L
D
I
I
K
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation