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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STXBP4
Full Name:
Syntaxin-binding protein 4
Alias:
MGC50337; STX4-interacting protein; STXB4; Synip; Syntaxin 4-interacting protein; Syntaxin binding protein 4
Type:
Vesicle protein
Mass (Da):
61761
Number AA:
553
UniProt ID:
Q6ZWJ1
International Prot ID:
IPI00217200
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006605
GO:0006810
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
N
K
N
T
S
T
V
V
S
P
S
Site 2
S6
_
_
M
N
K
N
T
S
T
V
V
S
P
S
L
Site 3
T7
_
M
N
K
N
T
S
T
V
V
S
P
S
L
L
Site 4
S10
K
N
T
S
T
V
V
S
P
S
L
L
E
K
D
Site 5
S12
T
S
T
V
V
S
P
S
L
L
E
K
D
P
A
Site 6
Y59
I
I
P
G
G
D
C
Y
K
D
G
R
L
K
P
Site 7
S72
K
P
G
D
Q
L
V
S
V
N
K
E
S
M
I
Site 8
S82
K
E
S
M
I
G
V
S
F
E
E
A
K
S
I
Site 9
S88
V
S
F
E
E
A
K
S
I
I
T
R
A
K
L
Site 10
S99
R
A
K
L
R
L
E
S
A
W
E
I
A
F
I
Site 11
S110
I
A
F
I
R
Q
K
S
D
N
I
Q
P
E
N
Site 12
S119
N
I
Q
P
E
N
L
S
C
T
S
L
I
E
A
Site 13
S122
P
E
N
L
S
C
T
S
L
I
E
A
S
G
E
Site 14
S135
G
E
Y
G
P
Q
A
S
T
L
S
L
F
S
S
Site 15
T136
E
Y
G
P
Q
A
S
T
L
S
L
F
S
S
P
Site 16
S138
G
P
Q
A
S
T
L
S
L
F
S
S
P
P
E
Site 17
T151
P
E
I
L
I
P
K
T
S
S
T
P
K
T
N
Site 18
S152
E
I
L
I
P
K
T
S
S
T
P
K
T
N
N
Site 19
S153
I
L
I
P
K
T
S
S
T
P
K
T
N
N
D
Site 20
T154
L
I
P
K
T
S
S
T
P
K
T
N
N
D
I
Site 21
T157
K
T
S
S
T
P
K
T
N
N
D
I
L
S
S
Site 22
S163
K
T
N
N
D
I
L
S
S
C
E
I
K
T
G
Site 23
S164
T
N
N
D
I
L
S
S
C
E
I
K
T
G
Y
Site 24
Y171
S
C
E
I
K
T
G
Y
N
K
T
V
Q
I
P
Site 25
T174
I
K
T
G
Y
N
K
T
V
Q
I
P
I
T
S
Site 26
T180
K
T
V
Q
I
P
I
T
S
E
N
S
T
V
G
Site 27
T185
P
I
T
S
E
N
S
T
V
G
L
S
N
T
D
Site 28
S189
E
N
S
T
V
G
L
S
N
T
D
V
A
S
A
Site 29
S208
Y
G
L
Q
E
K
I
S
L
N
P
S
V
R
F
Site 30
S212
E
K
I
S
L
N
P
S
V
R
F
K
A
E
K
Site 31
Y226
K
L
E
M
A
L
N
Y
L
G
I
Q
P
T
K
Site 32
S247
R
Q
Q
V
Q
A
D
S
K
G
T
V
S
F
G
Site 33
S284
E
I
S
N
I
L
D
S
Q
L
L
P
C
D
S
Site 34
S291
S
Q
L
L
P
C
D
S
S
E
A
D
E
M
E
Site 35
S292
Q
L
L
P
C
D
S
S
E
A
D
E
M
E
R
Site 36
Y370
A
H
G
M
E
M
D
Y
E
E
V
I
R
L
L
Site 37
Y391
L
K
A
Q
L
A
D
Y
S
D
Q
N
K
E
S
Site 38
S392
K
A
Q
L
A
D
Y
S
D
Q
N
K
E
S
V
Site 39
S398
Y
S
D
Q
N
K
E
S
V
Q
D
L
K
K
R
Site 40
S416
L
D
C
Q
L
R
K
S
E
M
A
R
K
T
F
Site 41
T422
K
S
E
M
A
R
K
T
F
E
A
S
T
E
K
Site 42
S426
A
R
K
T
F
E
A
S
T
E
K
L
L
H
F
Site 43
S442
E
A
I
Q
E
V
F
S
D
N
S
T
P
L
S
Site 44
S445
Q
E
V
F
S
D
N
S
T
P
L
S
N
L
S
Site 45
T446
E
V
F
S
D
N
S
T
P
L
S
N
L
S
E
Site 46
S449
S
D
N
S
T
P
L
S
N
L
S
E
R
R
A
Site 47
S452
S
T
P
L
S
N
L
S
E
R
R
A
V
L
A
Site 48
S460
E
R
R
A
V
L
A
S
Q
T
S
L
T
P
L
Site 49
S463
A
V
L
A
S
Q
T
S
L
T
P
L
G
R
N
Site 50
T465
L
A
S
Q
T
S
L
T
P
L
G
R
N
G
R
Site 51
T477
N
G
R
S
I
P
A
T
L
A
L
E
S
K
E
Site 52
S488
E
S
K
E
L
V
K
S
V
R
A
L
L
D
M
Site 53
Y506
P
Y
G
W
E
E
A
Y
T
A
D
G
I
K
Y
Site 54
Y513
Y
T
A
D
G
I
K
Y
F
I
N
H
V
T
Q
Site 55
S535
V
M
S
V
L
N
L
S
R
S
E
E
N
E
E
Site 56
S537
S
V
L
N
L
S
R
S
E
E
N
E
E
D
C
Site 57
S545
E
E
N
E
E
D
C
S
R
E
L
P
N
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation