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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TICAM-2
Full Name:
TIR domain-containing adapter molecule 2
Alias:
Putative NF-kappa-B-activating protein 502;TRIF-related adapter molecule;Toll-like receptor adaptor protein 3;Toll/interleukin-1 receptor domain-containing protein
Type:
Adapter/scaffold protein
Mass (Da):
26916
Number AA:
235
UniProt ID:
Q86XR7
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0031224
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0007249
GO:0006954
GO:0045087
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
I
G
K
S
K
I
N
S
C
P
L
S
L
S
W
Site 2
S14
K
I
N
S
C
P
L
S
L
S
W
G
K
R
H
Site 3
S16
N
S
C
P
L
S
L
S
W
G
K
R
H
S
V
Site 4
S22
L
S
W
G
K
R
H
S
V
D
T
S
P
G
Y
Site 5
T25
G
K
R
H
S
V
D
T
S
P
G
Y
H
E
S
Site 6
S26
K
R
H
S
V
D
T
S
P
G
Y
H
E
S
D
Site 7
Y29
S
V
D
T
S
P
G
Y
H
E
S
D
S
K
K
Site 8
S32
T
S
P
G
Y
H
E
S
D
S
K
K
S
E
D
Site 9
S34
P
G
Y
H
E
S
D
S
K
K
S
E
D
L
S
Site 10
S37
H
E
S
D
S
K
K
S
E
D
L
S
L
C
N
Site 11
S41
S
K
K
S
E
D
L
S
L
C
N
V
A
E
H
Site 12
T51
N
V
A
E
H
S
N
T
T
E
G
P
T
G
K
Site 13
S64
G
K
Q
E
G
A
Q
S
V
E
E
M
F
E
E
Site 14
T90
I
L
H
A
E
D
D
T
D
E
A
L
R
V
Q
Site 15
Y167
S
V
N
R
Q
H
K
Y
N
S
V
I
P
M
R
Site 16
S169
N
R
Q
H
K
Y
N
S
V
I
P
M
R
P
L
Site 17
T185
N
P
L
P
R
E
R
T
P
F
A
L
Q
T
I
Site 18
S213
V
E
R
I
F
Q
E
S
V
Y
K
T
Q
Q
T
Site 19
Y215
R
I
F
Q
E
S
V
Y
K
T
Q
Q
T
I
W
Site 20
T217
F
Q
E
S
V
Y
K
T
Q
Q
T
I
W
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation