KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
STK40
Full Name:
Serine/threonine-protein kinase 40
Alias:
SINK-homologous serine/threonine-protein kinase;Sugen kinase 495
Type:
Mass (Da):
49001
Number AA:
435
UniProt ID:
Q8N2I9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
K
R
R
A
S
D
R
G
A
G
E
T
Site 2
T13
S
D
R
G
A
G
E
T
S
A
R
A
K
A
L
Site 3
S14
D
R
G
A
G
E
T
S
A
R
A
K
A
L
G
Site 4
S44
L
G
P
R
L
G
N
S
P
V
P
S
I
V
Q
Site 5
Y63
K
D
G
T
D
D
F
Y
Q
L
K
I
L
T
L
Site 6
S80
R
G
D
Q
G
I
E
S
Q
E
E
R
Q
G
K
Site 7
S95
M
L
L
H
T
E
Y
S
L
L
S
L
L
H
T
Site 8
S98
H
T
E
Y
S
L
L
S
L
L
H
T
Q
D
G
Site 9
T117
H
G
L
F
Q
D
R
T
C
E
I
V
E
D
T
Site 10
T124
T
C
E
I
V
E
D
T
E
S
S
R
M
V
K
Site 11
S126
E
I
V
E
D
T
E
S
S
R
M
V
K
K
M
Site 12
T153
A
H
D
F
S
D
K
T
A
D
L
I
N
L
Q
Site 13
Y162
D
L
I
N
L
Q
H
Y
V
I
K
E
K
R
L
Site 14
S170
V
I
K
E
K
R
L
S
E
R
E
T
V
V
I
Site 15
T174
K
R
L
S
E
R
E
T
V
V
I
F
Y
D
V
Site 16
T213
N
K
R
T
H
R
I
T
I
T
N
F
C
L
G
Site 17
T215
R
T
H
R
I
T
I
T
N
F
C
L
G
K
H
Site 18
S236
L
L
K
D
Q
R
G
S
P
A
Y
I
S
P
D
Site 19
Y239
D
Q
R
G
S
P
A
Y
I
S
P
D
V
L
S
Site 20
S241
R
G
S
P
A
Y
I
S
P
D
V
L
S
G
R
Site 21
S246
Y
I
S
P
D
V
L
S
G
R
P
Y
R
G
K
Site 22
Y250
D
V
L
S
G
R
P
Y
R
G
K
P
S
D
M
Site 23
Y275
L
Y
G
Q
F
P
F
Y
D
S
I
P
Q
E
L
Site 24
S277
G
Q
F
P
F
Y
D
S
I
P
Q
E
L
F
R
Site 25
Y291
R
K
I
K
A
A
E
Y
T
I
P
E
D
G
R
Site 26
T303
D
G
R
V
S
E
N
T
V
C
L
I
R
K
L
Site 27
S339
I
A
S
W
Q
S
L
S
S
L
S
G
P
L
Q
Site 28
S340
A
S
W
Q
S
L
S
S
L
S
G
P
L
Q
V
Site 29
S356
P
D
I
D
D
Q
M
S
N
A
D
S
S
Q
E
Site 30
S360
D
Q
M
S
N
A
D
S
S
Q
E
A
K
V
T
Site 31
S361
Q
M
S
N
A
D
S
S
Q
E
A
K
V
T
E
Site 32
T367
S
S
Q
E
A
K
V
T
E
E
C
S
Q
Y
E
Site 33
S371
A
K
V
T
E
E
C
S
Q
Y
E
F
E
N
Y
Site 34
Y373
V
T
E
E
C
S
Q
Y
E
F
E
N
Y
M
R
Site 35
Y378
S
Q
Y
E
F
E
N
Y
M
R
Q
Q
L
L
L
Site 36
S390
L
L
L
A
E
E
K
S
S
I
H
D
A
R
S
Site 37
S391
L
L
A
E
E
K
S
S
I
H
D
A
R
S
W
Site 38
S397
S
S
I
H
D
A
R
S
W
V
P
K
R
Q
F
Site 39
S422
H
D
A
Q
P
M
T
S
L
D
T
A
I
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation