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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUP35
Full Name:
Nucleoporin NUP53
Alias:
35 kDa nucleoporin; Mitotic phosphoprotein 44; MP44; MP-44; NP44; Nuclear pore complex protein Nup53; Nucleoporin 35kDa; Nucleoporin Nup35; Nucleoporin NUP53; NUP53
Type:
Nuclear pore protein
Mass (Da):
34774
Number AA:
326
UniProt ID:
Q8NFH5
International Prot ID:
IPI00329650
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005643
GO:0005635
GO:0005643
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0015031
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
P
Q
G
P
A
L
G
S
E
P
M
M
L
G
S
Site 2
S22
S
E
P
M
M
L
G
S
P
T
S
P
K
P
G
Site 3
T24
P
M
M
L
G
S
P
T
S
P
K
P
G
V
N
Site 4
S25
M
M
L
G
S
P
T
S
P
K
P
G
V
N
A
Site 5
T48
G
D
L
P
A
P
V
T
P
Q
P
R
S
I
S
Site 6
S53
P
V
T
P
Q
P
R
S
I
S
G
P
S
V
G
Site 7
S55
T
P
Q
P
R
S
I
S
G
P
S
V
G
V
M
Site 8
S58
P
R
S
I
S
G
P
S
V
G
V
M
E
M
R
Site 9
S66
V
G
V
M
E
M
R
S
P
L
L
A
G
G
S
Site 10
S73
S
P
L
L
A
G
G
S
P
P
Q
P
V
V
P
Site 11
S86
V
P
A
H
K
D
K
S
G
A
P
P
V
R
S
Site 12
S93
S
G
A
P
P
V
R
S
I
Y
D
D
I
S
S
Site 13
Y95
A
P
P
V
R
S
I
Y
D
D
I
S
S
P
G
Site 14
S99
R
S
I
Y
D
D
I
S
S
P
G
L
G
S
T
Site 15
S100
S
I
Y
D
D
I
S
S
P
G
L
G
S
T
P
Site 16
S105
I
S
S
P
G
L
G
S
T
P
L
T
S
R
R
Site 17
T106
S
S
P
G
L
G
S
T
P
L
T
S
R
R
Q
Site 18
T109
G
L
G
S
T
P
L
T
S
R
R
Q
P
N
I
Site 19
S110
L
G
S
T
P
L
T
S
R
R
Q
P
N
I
S
Site 20
S117
S
R
R
Q
P
N
I
S
V
M
Q
S
P
L
V
Site 21
S121
P
N
I
S
V
M
Q
S
P
L
V
G
V
T
S
Site 22
S128
S
P
L
V
G
V
T
S
T
P
G
T
G
Q
S
Site 23
T129
P
L
V
G
V
T
S
T
P
G
T
G
Q
S
M
Site 24
T132
G
V
T
S
T
P
G
T
G
Q
S
M
F
S
P
Site 25
S135
S
T
P
G
T
G
Q
S
M
F
S
P
A
S
I
Site 26
S138
G
T
G
Q
S
M
F
S
P
A
S
I
G
Q
P
Site 27
S141
Q
S
M
F
S
P
A
S
I
G
Q
P
R
K
T
Site 28
T148
S
I
G
Q
P
R
K
T
T
L
S
P
A
Q
L
Site 29
T149
I
G
Q
P
R
K
T
T
L
S
P
A
Q
L
D
Site 30
S151
Q
P
R
K
T
T
L
S
P
A
Q
L
D
P
F
Site 31
Y159
P
A
Q
L
D
P
F
Y
T
Q
G
D
S
L
T
Site 32
T160
A
Q
L
D
P
F
Y
T
Q
G
D
S
L
T
S
Site 33
S164
P
F
Y
T
Q
G
D
S
L
T
S
E
D
H
L
Site 34
T166
Y
T
Q
G
D
S
L
T
S
E
D
H
L
D
D
Site 35
S174
S
E
D
H
L
D
D
S
W
V
T
V
F
G
F
Site 36
Y215
G
N
W
M
H
I
R
Y
Q
S
K
L
Q
A
R
Site 37
S226
L
Q
A
R
K
A
L
S
K
D
G
R
I
F
G
Site 38
S247
V
K
P
C
I
D
K
S
V
M
E
S
S
D
R
Site 39
S251
I
D
K
S
V
M
E
S
S
D
R
C
A
L
S
Site 40
S252
D
K
S
V
M
E
S
S
D
R
C
A
L
S
S
Site 41
S258
S
S
D
R
C
A
L
S
S
P
S
L
A
F
T
Site 42
S259
S
D
R
C
A
L
S
S
P
S
L
A
F
T
P
Site 43
S261
R
C
A
L
S
S
P
S
L
A
F
T
P
P
I
Site 44
T265
S
S
P
S
L
A
F
T
P
P
I
K
T
L
G
Site 45
T273
P
P
I
K
T
L
G
T
P
T
Q
P
G
S
T
Site 46
T275
I
K
T
L
G
T
P
T
Q
P
G
S
T
P
R
Site 47
S279
G
T
P
T
Q
P
G
S
T
P
R
I
S
T
M
Site 48
T280
T
P
T
Q
P
G
S
T
P
R
I
S
T
M
R
Site 49
S284
P
G
S
T
P
R
I
S
T
M
R
P
L
A
T
Site 50
T285
G
S
T
P
R
I
S
T
M
R
P
L
A
T
A
Site 51
S298
T
A
Y
K
A
S
T
S
D
Y
Q
V
I
S
D
Site 52
Y300
Y
K
A
S
T
S
D
Y
Q
V
I
S
D
R
Q
Site 53
S304
T
S
D
Y
Q
V
I
S
D
R
Q
T
P
K
K
Site 54
T308
Q
V
I
S
D
R
Q
T
P
K
K
D
E
S
L
Site 55
S314
Q
T
P
K
K
D
E
S
L
V
S
K
A
M
E
Site 56
S317
K
K
D
E
S
L
V
S
K
A
M
E
Y
M
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation