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Updated November 2019
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Protein Info
Short Name:
NUP210
Full Name:
Nuclear pore membrane glycoprotein 210
Alias:
FLJ22389; GP210; KIAA0906; Nucleoporin 210kDa; PO210; POM210
Type:
Membrane protein, integral; Nucleoporin
Mass (Da):
205111
Number AA:
1887
UniProt ID:
Q8TEM1
International Prot ID:
IPI00783433
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005643
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0015031
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T46
R
A
T
R
V
N
F
T
L
E
A
S
E
G
C
Site 2
Y54
L
E
A
S
E
G
C
Y
R
W
L
S
T
R
P
Site 3
S58
E
G
C
Y
R
W
L
S
T
R
P
E
V
A
S
Site 4
S65
S
T
R
P
E
V
A
S
I
E
P
L
G
L
D
Site 5
S77
G
L
D
E
Q
Q
C
S
Q
K
A
V
V
Q
A
Site 6
Y129
V
S
T
T
R
E
L
Y
L
E
D
S
P
L
E
Site 7
S133
R
E
L
Y
L
E
D
S
P
L
E
L
K
I
Q
Site 8
S144
L
K
I
Q
A
L
D
S
E
G
N
T
F
S
T
Site 9
S165
E
W
T
I
V
K
D
S
E
A
D
R
F
S
D
Site 10
S171
D
S
E
A
D
R
F
S
D
S
H
N
A
L
R
Site 11
S173
E
A
D
R
F
S
D
S
H
N
A
L
R
I
L
Site 12
S191
E
S
T
Y
I
P
P
S
Y
I
S
E
M
E
K
Site 13
Y192
S
T
Y
I
P
P
S
Y
I
S
E
M
E
K
A
Site 14
T205
K
A
A
K
Q
G
D
T
I
L
V
S
G
M
K
Site 15
S209
Q
G
D
T
I
L
V
S
G
M
K
T
G
S
S
Site 16
Y227
A
R
I
Q
E
A
V
Y
K
N
V
R
P
A
E
Site 17
T272
K
I
R
Q
G
K
I
T
E
L
S
M
P
S
D
Site 18
S275
Q
G
K
I
T
E
L
S
M
P
S
D
Q
Y
E
Site 19
Y281
L
S
M
P
S
D
Q
Y
E
L
Q
L
Q
N
S
Site 20
S288
Y
E
L
Q
L
Q
N
S
I
P
G
P
E
G
D
Site 21
S326
S
L
V
L
G
H
R
S
I
R
M
Q
G
A
S
Site 22
S333
S
I
R
M
Q
G
A
S
R
L
P
N
S
T
I
Site 23
S338
G
A
S
R
L
P
N
S
T
I
Y
V
V
E
P
Site 24
T339
A
S
R
L
P
N
S
T
I
Y
V
V
E
P
G
Site 25
Y341
R
L
P
N
S
T
I
Y
V
V
E
P
G
Y
L
Site 26
T351
E
P
G
Y
L
G
F
T
V
H
P
G
D
R
W
Site 27
T362
G
D
R
W
V
L
E
T
G
R
L
Y
E
I
T
Site 28
Y381
D
K
F
S
N
K
V
Y
V
S
D
N
I
R
I
Site 29
S383
F
S
N
K
V
Y
V
S
D
N
I
R
I
E
T
Site 30
S401
A
E
F
F
E
V
L
S
S
S
Q
N
G
S
Y
Site 31
S402
E
F
F
E
V
L
S
S
S
Q
N
G
S
Y
H
Site 32
S403
F
F
E
V
L
S
S
S
Q
N
G
S
Y
H
R
Site 33
S407
L
S
S
S
Q
N
G
S
Y
H
R
I
R
A
L
Site 34
Y408
S
S
S
Q
N
G
S
Y
H
R
I
R
A
L
K
Site 35
T419
R
A
L
K
R
G
Q
T
A
I
D
A
A
L
T
Site 36
T426
T
A
I
D
A
A
L
T
S
V
V
D
Q
D
G
Site 37
T462
T
L
Y
P
S
I
L
T
F
P
W
Q
P
K
T
Site 38
T469
T
F
P
W
Q
P
K
T
G
A
Y
Q
Y
T
I
Site 39
Y474
P
K
T
G
A
Y
Q
Y
T
I
R
A
H
G
G
Site 40
T475
K
T
G
A
Y
Q
Y
T
I
R
A
H
G
G
S
Site 41
S482
T
I
R
A
H
G
G
S
G
N
F
S
W
S
S
Site 42
S486
H
G
G
S
G
N
F
S
W
S
S
S
S
H
L
Site 43
S488
G
S
G
N
F
S
W
S
S
S
S
H
L
V
A
Site 44
S489
S
G
N
F
S
W
S
S
S
S
H
L
V
A
T
Site 45
S490
G
N
F
S
W
S
S
S
S
H
L
V
A
T
V
Site 46
S491
N
F
S
W
S
S
S
S
H
L
V
A
T
V
T
Site 47
Y531
H
F
G
E
M
K
V
Y
V
I
E
P
H
S
M
Site 48
S602
P
G
R
L
P
P
G
S
E
H
C
S
G
I
R
Site 49
S606
P
P
G
S
E
H
C
S
G
I
R
V
K
A
E
Site 50
T619
A
E
A
Q
G
S
T
T
L
L
V
S
Y
R
H
Site 51
S623
G
S
T
T
L
L
V
S
Y
R
H
G
H
V
H
Site 52
S649
P
L
K
A
V
D
P
S
S
V
A
L
V
T
L
Site 53
S659
A
L
V
T
L
G
S
S
K
E
M
L
F
E
G
Site 54
T687
Q
N
V
T
A
E
D
T
D
S
I
G
L
A
L
Site 55
S699
L
A
L
F
A
P
H
S
S
R
N
Y
Q
Q
H
Site 56
Y703
A
P
H
S
S
R
N
Y
Q
Q
H
W
I
L
V
Site 57
S729
L
S
V
G
N
K
P
S
L
T
N
P
F
P
A
Site 58
T731
V
G
N
K
P
S
L
T
N
P
F
P
A
V
E
Site 59
Y758
R
L
T
L
A
P
V
Y
T
S
P
Q
L
D
M
Site 60
S766
T
S
P
Q
L
D
M
S
C
P
L
L
Q
Q
N
Site 61
S780
N
K
Q
V
V
P
V
S
S
H
R
N
P
R
L
Site 62
S781
K
Q
V
V
P
V
S
S
H
R
N
P
R
L
D
Site 63
Y792
P
R
L
D
L
A
A
Y
D
Q
E
G
R
R
F
Site 64
S803
G
R
R
F
D
N
F
S
S
L
S
I
Q
W
E
Site 65
S804
R
R
F
D
N
F
S
S
L
S
I
Q
W
E
S
Site 66
S806
F
D
N
F
S
S
L
S
I
Q
W
E
S
T
R
Site 67
S811
S
L
S
I
Q
W
E
S
T
R
P
V
L
A
S
Site 68
S818
S
T
R
P
V
L
A
S
I
E
P
E
L
P
M
Site 69
S829
E
L
P
M
Q
L
V
S
Q
D
D
E
S
G
Q
Site 70
S834
L
V
S
Q
D
D
E
S
G
Q
K
K
L
H
G
Site 71
Y863
I
T
A
T
A
T
G
Y
Q
E
S
H
L
S
S
Site 72
S866
T
A
T
G
Y
Q
E
S
H
L
S
S
A
R
T
Site 73
S869
G
Y
Q
E
S
H
L
S
S
A
R
T
K
Q
P
Site 74
S870
Y
Q
E
S
H
L
S
S
A
R
T
K
Q
P
H
Site 75
T873
S
H
L
S
S
A
R
T
K
Q
P
H
D
P
L
Site 76
Y905
S
P
E
E
V
T
I
Y
N
H
P
G
I
Q
A
Site 77
S920
E
L
R
I
R
E
G
S
G
Y
F
F
L
N
T
Site 78
Y922
R
I
R
E
G
S
G
Y
F
F
L
N
T
S
T
Site 79
T994
D
K
V
E
I
G
K
T
V
K
A
Y
V
R
V
Site 80
Y1013
K
K
P
F
L
A
K
Y
F
P
F
M
D
L
K
Site 81
S1059
G
Q
T
S
L
T
A
S
V
T
N
K
A
G
Q
Site 82
S1070
K
A
G
Q
R
I
N
S
A
P
Q
Q
I
E
V
Site 83
S1108
E
G
G
P
Q
P
Q
S
N
I
L
F
S
I
S
Site 84
S1113
P
Q
S
N
I
L
F
S
I
S
N
E
S
V
A
Site 85
T1181
A
P
I
M
R
M
R
T
G
T
Q
M
P
I
Y
Site 86
Y1188
T
G
T
Q
M
P
I
Y
V
T
G
I
T
N
H
Site 87
S1200
T
N
H
Q
N
P
F
S
F
G
N
A
V
P
G
Site 88
T1209
G
N
A
V
P
G
L
T
F
H
W
S
V
T
K
Site 89
S1213
P
G
L
T
F
H
W
S
V
T
K
R
D
V
L
Site 90
T1215
L
T
F
H
W
S
V
T
K
R
D
V
L
D
L
Site 91
S1230
R
G
R
H
H
E
A
S
I
R
L
P
S
Q
Y
Site 92
S1235
E
A
S
I
R
L
P
S
Q
Y
N
F
A
M
N
Site 93
Y1268
D
P
T
S
G
Q
L
Y
G
L
A
R
E
L
S
Site 94
S1275
Y
G
L
A
R
E
L
S
D
E
I
Q
V
Q
V
Site 95
S1301
E
A
E
Q
I
L
M
S
P
N
S
Y
I
K
L
Site 96
S1304
Q
I
L
M
S
P
N
S
Y
I
K
L
Q
T
N
Site 97
Y1305
I
L
M
S
P
N
S
Y
I
K
L
Q
T
N
R
Site 98
T1310
N
S
Y
I
K
L
Q
T
N
R
D
G
A
A
S
Site 99
S1317
T
N
R
D
G
A
A
S
L
S
Y
R
V
L
D
Site 100
S1319
R
D
G
A
A
S
L
S
Y
R
V
L
D
G
P
Site 101
S1342
D
E
K
G
F
L
A
S
G
S
M
I
G
T
S
Site 102
S1382
S
Y
L
R
V
S
M
S
P
V
L
H
T
Q
N
Site 103
T1427
S
S
V
L
N
F
A
T
N
R
D
D
F
V
Q
Site 104
T1443
G
K
G
P
T
N
N
T
C
V
V
R
T
V
S
Site 105
S1467
D
A
E
H
P
G
L
S
D
F
M
P
L
P
V
Site 106
S1505
L
T
S
L
E
G
L
S
G
T
W
S
S
S
A
Site 107
T1507
S
L
E
G
L
S
G
T
W
S
S
S
A
N
S
Site 108
S1509
E
G
L
S
G
T
W
S
S
S
A
N
S
I
L
Site 109
S1510
G
L
S
G
T
W
S
S
S
A
N
S
I
L
H
Site 110
S1514
T
W
S
S
S
A
N
S
I
L
H
I
D
P
K
Site 111
S1568
H
L
H
P
I
Q
T
S
F
Q
E
A
T
A
S
Site 112
T1573
Q
T
S
F
Q
E
A
T
A
S
K
V
I
V
A
Site 113
S1585
I
V
A
V
G
D
R
S
S
N
L
R
G
E
C
Site 114
S1586
V
A
V
G
D
R
S
S
N
L
R
G
E
C
T
Site 115
T1593
S
N
L
R
G
E
C
T
P
T
Q
R
E
V
I
Site 116
T1595
L
R
G
E
C
T
P
T
Q
R
E
V
I
Q
A
Site 117
T1607
I
Q
A
L
H
P
E
T
L
I
S
C
Q
S
Q
Site 118
S1610
L
H
P
E
T
L
I
S
C
Q
S
Q
F
K
P
Site 119
T1629
F
P
S
Q
D
V
F
T
V
E
P
Q
F
D
T
Site 120
T1651
S
I
T
M
H
R
L
T
D
K
Q
R
K
H
L
Site 121
S1659
D
K
Q
R
K
H
L
S
M
K
K
T
A
L
V
Site 122
S1668
K
K
T
A
L
V
V
S
A
S
L
S
S
S
H
Site 123
S1673
V
V
S
A
S
L
S
S
S
H
F
S
T
E
Q
Site 124
S1674
V
S
A
S
L
S
S
S
H
F
S
T
E
Q
V
Site 125
S1677
S
L
S
S
S
H
F
S
T
E
Q
V
G
A
E
Site 126
T1678
L
S
S
S
H
F
S
T
E
Q
V
G
A
E
V
Site 127
S1701
D
Q
A
E
I
L
L
S
N
H
Y
T
S
S
E
Site 128
Y1704
E
I
L
L
S
N
H
Y
T
S
S
E
I
R
V
Site 129
S1727
N
L
E
V
K
S
G
S
P
A
V
L
A
F
A
Site 130
S1743
E
K
S
F
G
W
P
S
F
I
T
Y
T
V
G
Site 131
S1758
V
L
D
P
A
A
G
S
Q
G
P
L
S
T
T
Site 132
S1763
A
G
S
Q
G
P
L
S
T
T
L
T
F
S
S
Site 133
T1764
G
S
Q
G
P
L
S
T
T
L
T
F
S
S
P
Site 134
T1765
S
Q
G
P
L
S
T
T
L
T
F
S
S
P
V
Site 135
T1767
G
P
L
S
T
T
L
T
F
S
S
P
V
T
N
Site 136
S1769
L
S
T
T
L
T
F
S
S
P
V
T
N
Q
A
Site 137
T1773
L
T
F
S
S
P
V
T
N
Q
A
I
A
I
P
Site 138
Y1795
D
R
R
G
P
G
P
Y
G
A
S
L
F
Q
H
Site 139
S1798
G
P
G
P
Y
G
A
S
L
F
Q
H
F
L
D
Site 140
T1844
L
A
V
P
A
A
L
T
P
R
A
S
P
G
H
Site 141
S1848
A
A
L
T
P
R
A
S
P
G
H
S
P
H
Y
Site 142
S1852
P
R
A
S
P
G
H
S
P
H
Y
F
A
A
S
Site 143
Y1855
S
P
G
H
S
P
H
Y
F
A
A
S
S
P
T
Site 144
S1859
S
P
H
Y
F
A
A
S
S
P
T
S
P
N
A
Site 145
S1860
P
H
Y
F
A
A
S
S
P
T
S
P
N
A
L
Site 146
T1862
Y
F
A
A
S
S
P
T
S
P
N
A
L
P
P
Site 147
S1863
F
A
A
S
S
P
T
S
P
N
A
L
P
P
A
Site 148
S1874
L
P
P
A
R
K
A
S
P
P
S
G
L
W
S
Site 149
S1877
A
R
K
A
S
P
P
S
G
L
W
S
P
A
Y
Site 150
S1881
S
P
P
S
G
L
W
S
P
A
Y
A
S
H
_
Site 151
Y1884
S
G
L
W
S
P
A
Y
A
S
H
_
_
_
_
Site 152
S1886
L
W
S
P
A
Y
A
S
H
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation