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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CKAP2
Full Name:
Cytoskeleton-associated protein 2
Alias:
Cytoskeleton associated 2; Cytoskeleton associated protein 2; FLJ10749; LB1; Se20-10; TMAP; Tumor- and microtubule-associated protein; Tumor-associated microtubule-associated
Type:
Cell cycle regulation
Mass (Da):
76987
Number AA:
683
UniProt ID:
Q8WWK9
International Prot ID:
IPI00071824
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
GO:0044422
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007049
GO:0008219
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
T
P
A
V
P
Q
D
Site 2
T3
_
_
_
_
_
M
S
T
P
A
V
P
Q
D
L
Site 3
S15
Q
D
L
Q
L
P
P
S
Q
R
A
Q
S
A
F
Site 4
S20
P
P
S
Q
R
A
Q
S
A
F
K
E
Q
R
R
Site 5
T39
E
H
L
L
R
R
K
T
L
F
A
Y
K
Q
E
Site 6
S51
K
Q
E
N
E
M
L
S
S
S
R
D
Q
R
V
Site 7
S52
Q
E
N
E
M
L
S
S
S
R
D
Q
R
V
V
Site 8
T60
S
R
D
Q
R
V
V
T
S
E
D
Q
V
Q
E
Site 9
T94
P
A
E
S
K
N
N
T
V
V
G
K
H
C
I
Site 10
T110
L
K
P
S
N
E
L
T
N
S
T
V
V
I
D
Site 11
S112
P
S
N
E
L
T
N
S
T
V
V
I
D
T
H
Site 12
T113
S
N
E
L
T
N
S
T
V
V
I
D
T
H
K
Site 13
T118
N
S
T
V
V
I
D
T
H
K
P
K
D
S
N
Site 14
T127
K
P
K
D
S
N
Q
T
P
H
L
L
L
T
E
Site 15
T133
Q
T
P
H
L
L
L
T
E
D
D
P
Q
S
Q
Site 16
S139
L
T
E
D
D
P
Q
S
Q
H
M
T
L
S
Q
Site 17
T143
D
P
Q
S
Q
H
M
T
L
S
Q
A
F
H
L
Site 18
S145
Q
S
Q
H
M
T
L
S
Q
A
F
H
L
K
N
Site 19
S178
P
K
K
P
V
L
G
S
Y
R
G
Q
I
V
Q
Site 20
S186
Y
R
G
Q
I
V
Q
S
K
I
N
S
F
R
K
Site 21
S190
I
V
Q
S
K
I
N
S
F
R
K
P
L
Q
V
Site 22
T205
K
D
E
S
S
A
A
T
K
K
L
S
A
T
I
Site 23
S209
S
A
A
T
K
K
L
S
A
T
I
P
K
A
T
Site 24
S225
P
Q
P
V
N
T
S
S
V
T
V
K
S
N
R
Site 25
T227
P
V
N
T
S
S
V
T
V
K
S
N
R
S
S
Site 26
S230
T
S
S
V
T
V
K
S
N
R
S
S
N
M
T
Site 27
S234
T
V
K
S
N
R
S
S
N
M
T
A
T
T
K
Site 28
T237
S
N
R
S
S
N
M
T
A
T
T
K
F
V
S
Site 29
T240
S
S
N
M
T
A
T
T
K
F
V
S
T
T
S
Site 30
S247
T
K
F
V
S
T
T
S
Q
N
T
Q
L
V
R
Site 31
S259
L
V
R
P
P
I
R
S
H
H
S
N
T
R
D
Site 32
S262
P
P
I
R
S
H
H
S
N
T
R
D
T
V
K
Site 33
T267
H
H
S
N
T
R
D
T
V
K
Q
G
I
S
R
Site 34
S276
K
Q
G
I
S
R
T
S
A
N
V
T
I
R
K
Site 35
T280
S
R
T
S
A
N
V
T
I
R
K
G
P
H
E
Site 36
S293
H
E
K
E
L
L
Q
S
K
T
A
L
S
S
V
Site 37
T295
K
E
L
L
Q
S
K
T
A
L
S
S
V
K
T
Site 38
S298
L
Q
S
K
T
A
L
S
S
V
K
T
S
S
S
Site 39
S299
Q
S
K
T
A
L
S
S
V
K
T
S
S
S
Q
Site 40
S303
A
L
S
S
V
K
T
S
S
S
Q
G
I
I
R
Site 41
S304
L
S
S
V
K
T
S
S
S
Q
G
I
I
R
N
Site 42
S305
S
S
V
K
T
S
S
S
Q
G
I
I
R
N
K
Site 43
T313
Q
G
I
I
R
N
K
T
L
S
R
S
I
A
S
Site 44
S315
I
I
R
N
K
T
L
S
R
S
I
A
S
E
V
Site 45
S317
R
N
K
T
L
S
R
S
I
A
S
E
V
I
A
Site 46
S320
T
L
S
R
S
I
A
S
E
V
I
A
R
P
A
Site 47
S328
E
V
I
A
R
P
A
S
L
S
N
D
K
L
M
Site 48
S330
I
A
R
P
A
S
L
S
N
D
K
L
M
E
K
Site 49
S338
N
D
K
L
M
E
K
S
E
P
V
D
Q
R
R
Site 50
T347
P
V
D
Q
R
R
H
T
A
G
K
A
I
V
D
Site 51
S355
A
G
K
A
I
V
D
S
R
S
A
Q
P
K
E
Site 52
S357
K
A
I
V
D
S
R
S
A
Q
P
K
E
T
S
Site 53
S372
E
E
R
K
A
R
L
S
E
W
K
A
G
K
G
Site 54
S388
V
L
K
R
P
P
N
S
V
V
T
Q
H
E
P
Site 55
S405
Q
N
E
K
P
V
G
S
F
W
T
T
M
A
E
Site 56
T409
P
V
G
S
F
W
T
T
M
A
E
E
D
E
Q
Site 57
T420
E
D
E
Q
R
L
F
T
E
K
V
N
N
T
F
Site 58
T426
F
T
E
K
V
N
N
T
F
S
E
C
L
N
L
Site 59
T507
H
T
I
V
D
I
L
T
M
K
S
Q
E
K
A
Site 60
S510
V
D
I
L
T
M
K
S
Q
E
K
A
N
L
G
Site 61
S523
L
G
E
N
M
E
K
S
C
A
S
K
E
E
V
Site 62
S534
K
E
E
V
K
E
V
S
I
E
D
T
G
V
D
Site 63
T538
K
E
V
S
I
E
D
T
G
V
D
V
D
P
E
Site 64
T570
E
K
E
Q
D
N
K
T
K
D
P
T
H
D
V
Site 65
T574
D
N
K
T
K
D
P
T
H
D
V
K
T
P
N
Site 66
T579
D
P
T
H
D
V
K
T
P
N
T
E
T
R
T
Site 67
T582
H
D
V
K
T
P
N
T
E
T
R
T
S
C
L
Site 68
S587
P
N
T
E
T
R
T
S
C
L
I
K
Y
N
V
Site 69
Y592
R
T
S
C
L
I
K
Y
N
V
S
T
T
P
Y
Site 70
S595
C
L
I
K
Y
N
V
S
T
T
P
Y
L
Q
S
Site 71
T596
L
I
K
Y
N
V
S
T
T
P
Y
L
Q
S
V
Site 72
T597
I
K
Y
N
V
S
T
T
P
Y
L
Q
S
V
K
Site 73
Y599
Y
N
V
S
T
T
P
Y
L
Q
S
V
K
K
K
Site 74
S602
S
T
T
P
Y
L
Q
S
V
K
K
K
V
Q
F
Site 75
T612
K
K
V
Q
F
D
G
T
N
S
A
F
K
E
L
Site 76
S614
V
Q
F
D
G
T
N
S
A
F
K
E
L
K
F
Site 77
T623
F
K
E
L
K
F
L
T
P
V
R
R
S
R
R
Site 78
S628
F
L
T
P
V
R
R
S
R
R
L
Q
E
K
T
Site 79
T635
S
R
R
L
Q
E
K
T
S
K
L
P
D
M
L
Site 80
S636
R
R
L
Q
E
K
T
S
K
L
P
D
M
L
K
Site 81
Y646
P
D
M
L
K
D
H
Y
P
C
V
S
S
L
E
Site 82
S651
D
H
Y
P
C
V
S
S
L
E
Q
L
T
E
L
Site 83
T662
L
T
E
L
G
R
E
T
D
A
F
V
C
R
P
Site 84
Y677
N
A
A
L
C
R
V
Y
Y
E
A
D
T
T
_
Site 85
Y678
A
A
L
C
R
V
Y
Y
E
A
D
T
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation