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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DPF2
Full Name:
Zinc finger protein ubi-d4
Alias:
Apoptosis response zinc finger protein; D4, zinc and double PHD fingers family 2; REQ; REQU; Requiem; UBID4; Ubi-d4; Zinc-finger protein ubi-d4
Type:
Apoptosis
Mass (Da):
44155
Number AA:
391
UniProt ID:
Q92785
International Prot ID:
IPI00023322
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0008624
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
V
K
L
L
G
E
Q
Y
Y
K
D
A
M
E
Q
Site 2
Y17
K
L
L
G
E
Q
Y
Y
K
D
A
M
E
Q
C
Site 3
Y27
A
M
E
Q
C
H
N
Y
N
A
R
L
C
A
E
Site 4
S44
V
R
L
P
F
L
D
S
Q
T
G
V
A
Q
S
Site 5
T46
L
P
F
L
D
S
Q
T
G
V
A
Q
S
N
C
Site 6
Y72
G
L
A
S
G
Q
L
Y
S
Y
P
A
R
R
W
Site 7
S73
L
A
S
G
Q
L
Y
S
Y
P
A
R
R
W
R
Site 8
Y74
A
S
G
Q
L
Y
S
Y
P
A
R
R
W
R
K
Site 9
S94
P
P
E
D
P
R
L
S
F
P
S
I
K
P
D
Site 10
S97
D
P
R
L
S
F
P
S
I
K
P
D
T
D
Q
Site 11
T102
F
P
S
I
K
P
D
T
D
Q
T
L
K
K
E
Site 12
T105
I
K
P
D
T
D
Q
T
L
K
K
E
G
L
I
Site 13
S113
L
K
K
E
G
L
I
S
Q
D
G
S
S
L
E
Site 14
S142
D
P
R
V
D
D
D
S
L
G
E
F
P
V
T
Site 15
T149
S
L
G
E
F
P
V
T
N
S
R
A
R
K
R
Site 16
S151
G
E
F
P
V
T
N
S
R
A
R
K
R
I
L
Site 17
Y172
D
D
L
D
D
E
D
Y
E
E
D
T
P
K
R
Site 18
T176
D
E
D
Y
E
E
D
T
P
K
R
R
G
K
G
Site 19
S185
K
R
R
G
K
G
K
S
K
G
K
G
V
G
S
Site 20
S192
S
K
G
K
G
V
G
S
A
R
K
K
L
D
A
Site 21
S200
A
R
K
K
L
D
A
S
I
L
E
D
R
D
K
Site 22
Y209
L
E
D
R
D
K
P
Y
A
C
D
I
C
G
K
Site 23
Y218
C
D
I
C
G
K
R
Y
K
N
R
P
G
L
S
Site 24
Y226
K
N
R
P
G
L
S
Y
H
Y
A
H
S
H
L
Site 25
S231
L
S
Y
H
Y
A
H
S
H
L
A
E
E
E
G
Site 26
S244
E
G
E
D
K
E
D
S
Q
P
P
T
P
V
S
Site 27
T248
K
E
D
S
Q
P
P
T
P
V
S
Q
R
S
E
Site 28
S251
S
Q
P
P
T
P
V
S
Q
R
S
E
E
Q
K
Site 29
S259
Q
R
S
E
E
Q
K
S
K
K
G
P
D
G
L
Site 30
T286
D
S
K
I
N
K
K
T
G
Q
P
E
E
L
V
Site 31
S294
G
Q
P
E
E
L
V
S
C
S
D
C
G
R
S
Site 32
S296
P
E
E
L
V
S
C
S
D
C
G
R
S
G
H
Site 33
S301
S
C
S
D
C
G
R
S
G
H
P
S
C
L
Q
Site 34
S305
C
G
R
S
G
H
P
S
C
L
Q
F
T
P
V
Site 35
T310
H
P
S
C
L
Q
F
T
P
V
M
M
A
A
V
Site 36
T358
G
Y
H
M
Y
C
L
T
P
S
M
S
E
P
P
Site 37
S360
H
M
Y
C
L
T
P
S
M
S
E
P
P
E
G
Site 38
S362
Y
C
L
T
P
S
M
S
E
P
P
E
G
S
W
Site 39
S370
E
P
P
E
G
S
W
S
C
H
L
C
L
D
L
Site 40
S383
D
L
L
K
E
K
A
S
I
Y
Q
N
Q
N
S
Site 41
Y385
L
K
E
K
A
S
I
Y
Q
N
Q
N
S
S
_
Site 42
S390
S
I
Y
Q
N
Q
N
S
S
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation