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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PYCR2
Full Name:
Pyrroline-5-carboxylate reductase 2
Alias:
EC 1.5.1.2; P5C reductase 2; P5CR 2; P5CR2
Type:
Oxidoreductase, Amino Acid Metabolism group, Arginine and proline metabolism family, Urea cycle and metabolism of amino groups family
Mass (Da):
33637
Number AA:
320
UniProt ID:
Q96C36
International Prot ID:
IPI00470610
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0004735
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0006561
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
V
G
F
I
G
A
G
Site 2
Y13
I
G
A
G
Q
L
A
Y
A
L
A
R
G
F
T
Site 3
S33
S
A
H
K
I
I
A
S
S
P
E
M
N
L
P
Site 4
S34
A
H
K
I
I
A
S
S
P
E
M
N
L
P
T
Site 5
T41
S
P
E
M
N
L
P
T
V
S
A
L
R
K
M
Site 6
T59
L
T
R
S
N
K
E
T
V
K
H
S
D
V
L
Site 7
S233
Q
L
K
D
N
V
C
S
P
G
G
A
T
I
H
Site 8
S278
M
A
D
Q
E
K
I
S
P
A
A
L
K
K
T
Site 9
T285
S
P
A
A
L
K
K
T
L
L
D
R
V
K
L
Site 10
S294
L
D
R
V
K
L
E
S
P
T
V
S
T
L
T
Site 11
T296
R
V
K
L
E
S
P
T
V
S
T
L
T
P
S
Site 12
S298
K
L
E
S
P
T
V
S
T
L
T
P
S
S
P
Site 13
T299
L
E
S
P
T
V
S
T
L
T
P
S
S
P
G
Site 14
T301
S
P
T
V
S
T
L
T
P
S
S
P
G
K
L
Site 15
S303
T
V
S
T
L
T
P
S
S
P
G
K
L
L
T
Site 16
S304
V
S
T
L
T
P
S
S
P
G
K
L
L
T
R
Site 17
T310
S
S
P
G
K
L
L
T
R
S
L
A
L
G
G
Site 18
S312
P
G
K
L
L
T
R
S
L
A
L
G
G
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation