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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PELI1
Full Name:
Protein pellino homolog 1
Alias:
Pellino 1; Pellino-1; Pellino-related intracellular signaling molecule; Pellino-related intracellular signalling molecule; PRISM
Type:
Ubiquitin conjugating system; Adaptor/scaffold; Ubiquitin ligase
Mass (Da):
46286
Number AA:
418
UniProt ID:
Q96FA3
International Prot ID:
IPI00034167
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
P
D
Q
E
N
H
P
S
K
A
P
V
K
Y
G
Site 2
S28
I
V
L
G
Y
N
G
S
L
P
N
G
D
R
G
Site 3
S39
G
D
R
G
R
R
K
S
R
F
A
L
F
K
R
Site 4
S55
K
A
N
G
V
K
P
S
T
V
H
I
A
C
T
Site 5
S70
P
Q
A
A
K
A
I
S
N
K
D
Q
H
S
I
Site 6
S76
I
S
N
K
D
Q
H
S
I
S
Y
T
L
S
R
Site 7
S78
N
K
D
Q
H
S
I
S
Y
T
L
S
R
A
Q
Site 8
T80
D
Q
H
S
I
S
Y
T
L
S
R
A
Q
T
V
Site 9
S82
H
S
I
S
Y
T
L
S
R
A
Q
T
V
V
V
Site 10
T86
Y
T
L
S
R
A
Q
T
V
V
V
E
Y
T
H
Site 11
T106
M
F
Q
I
G
R
S
T
E
S
P
I
D
F
V
Site 12
S108
Q
I
G
R
S
T
E
S
P
I
D
F
V
V
T
Site 13
T117
I
D
F
V
V
T
D
T
V
P
G
S
Q
S
N
Site 14
S121
V
T
D
T
V
P
G
S
Q
S
N
S
D
T
Q
Site 15
S123
D
T
V
P
G
S
Q
S
N
S
D
T
Q
S
V
Site 16
S125
V
P
G
S
Q
S
N
S
D
T
Q
S
V
Q
S
Site 17
T127
G
S
Q
S
N
S
D
T
Q
S
V
Q
S
T
I
Site 18
S129
Q
S
N
S
D
T
Q
S
V
Q
S
T
I
S
R
Site 19
S132
S
D
T
Q
S
V
Q
S
T
I
S
R
F
A
C
Site 20
T133
D
T
Q
S
V
Q
S
T
I
S
R
F
A
C
R
Site 21
T150
C
E
R
N
P
P
F
T
A
R
I
Y
A
A
G
Site 22
Y154
P
P
F
T
A
R
I
Y
A
A
G
F
D
S
S
Site 23
S161
Y
A
A
G
F
D
S
S
K
N
I
F
L
G
E
Site 24
S201
R
N
G
F
T
E
D
S
K
P
G
I
W
R
E
Site 25
S217
S
V
C
G
N
V
F
S
L
R
E
T
R
S
A
Site 26
T221
N
V
F
S
L
R
E
T
R
S
A
Q
Q
R
G
Site 27
S223
F
S
L
R
E
T
R
S
A
Q
Q
R
G
K
M
Site 28
S242
T
N
Q
L
Q
D
G
S
L
I
D
L
C
G
A
Site 29
T262
T
A
E
G
L
S
H
T
P
T
V
K
H
L
E
Site 30
T264
E
G
L
S
H
T
P
T
V
K
H
L
E
A
L
Site 31
T288
Q
C
P
V
G
F
N
T
L
A
F
P
S
M
K
Site 32
S293
F
N
T
L
A
F
P
S
M
K
R
K
D
V
V
Site 33
S338
R
E
C
P
M
C
R
S
V
G
P
Y
V
P
L
Site 34
T361
Y
V
D
A
G
P
P
T
H
A
F
S
P
C
G
Site 35
S365
G
P
P
T
H
A
F
S
P
C
G
H
V
C
S
Site 36
Y378
C
S
E
K
T
T
A
Y
W
S
Q
I
P
L
P
Site 37
S380
E
K
T
T
A
Y
W
S
Q
I
P
L
P
H
G
Site 38
T390
P
L
P
H
G
T
H
T
F
H
A
A
C
P
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation