PhosphoNET

           
Protein Info 
   
Short Name:  PAWR
Full Name:  PRKC apoptosis WT1 regulator protein
Alias:  PAR4; Par-4; PRKC, apoptosis, WT1, regulator; Prostate apoptosis response 4 protein; Prostate apoptosis response protein 4; Prostate apoptosis response protein PAR-4; Prostate apoptosis response-4 protein; Transcriptional repressor PAR4; WT1-interacting protein
Type:  Apoptosis protein
Mass (Da):  36568
Number AA:  340
UniProt ID:  Q96IZ0
International Prot ID:  IPI00001871
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0019899  GO:0043522  GO:0003714 PhosphoSite+ KinaseNET
Biological Process:  GO:0006915  GO:0000122  GO:0043065 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T8MATGGYRTSSGLGGS
Site 2S9ATGGYRTSSGLGGST
Site 3S10TGGYRTSSGLGGSTT
Site 4S15TSSGLGGSTTDFLEE
Site 5T16SSGLGGSTTDFLEEW
Site 6T17SGLGGSTTDFLEEWK
Site 7S47APPGGGSSDAAGKPP
Site 8S108AAPGPRRSEDEPPAA
Site 9S116EDEPPAASASAAPPP
Site 10S118EPPAASASAAPPPQR
Site 11S139GVPEKGKSSGPSARK
Site 12S143KGKSSGPSARKGKGQ
Site 13S162KLREKRRSTGVVNIP
Site 14T163LREKRRSTGVVNIPA
Site 15Y177AAECLDEYEDDEAGQ
Site 16T194RKREDAITQQNTIQN
Site 17S211VNLLDPGSSYLLQEP
Site 18Y213LLDPGSSYLLQEPPR
Site 19T221LLQEPPRTVSGRYKS
Site 20S223QEPPRTVSGRYKSTT
Site 21Y226PRTVSGRYKSTTSVS
Site 22S228TVSGRYKSTTSVSEE
Site 23T229VSGRYKSTTSVSEED
Site 24T230SGRYKSTTSVSEEDV
Site 25S231GRYKSTTSVSEEDVS
Site 26S233YKSTTSVSEEDVSSR
Site 27S238SVSEEDVSSRYSRTD
Site 28S239VSEEDVSSRYSRTDR
Site 29Y241EEDVSSRYSRTDRSG
Site 30S242EDVSSRYSRTDRSGF
Site 31T244VSSRYSRTDRSGFPR
Site 32S247RYSRTDRSGFPRYNR
Site 33Y252DRSGFPRYNRDANVS
Site 34S259YNRDANVSGTLVSSS
Site 35T261RDANVSGTLVSSSTL
Site 36S266SGTLVSSSTLEKKIE
Site 37T267GTLVSSSTLEKKIED
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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