PhosphoNET

           
Protein Info 
   
Short Name:  EGLN2
Full Name:  Egl nine homolog 2
Alias:  EC 1.14.11.-; EGL nine; EIT6; Estrogen-induced tag 6; HIF-PH1; HIF-prolyl hydroxylase 1; HPH-3; Hypoxia-inducible factor prolyl hydroxylase 1; PHD1; Prolyl hydroxylase domain-containing 1
Type: 
Mass (Da):  43650
Number AA:  407
UniProt ID:  Q96KS0
International Prot ID:  IPI00074957
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0031418  GO:0008198  GO:0016706 PhosphoSite+ KinaseNET
Biological Process:  GO:0045454  GO:0030520  GO:0055114 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11PCQPQPLSQALPQLP
Site 2S20ALPQLPGSSSEPLEP
Site 3S22PQLPGSSSEPLEPEP
Site 4S55YHCPGVPSEASAGSG
Site 5S58PGVPSEASAGSGTPR
Site 6S61PSEASAGSGTPRATA
Site 7T63EASAGSGTPRATATS
Site 8T67GSGTPRATATSTTAS
Site 9T69GTPRATATSTTASPL
Site 10S70TPRATATSTTASPLR
Site 11S74TATSTTASPLRDGFG
Site 12S130EDGGDAPSPSKRPWA
Site 13S132GGDAPSPSKRPWARQ
Site 14S151AEREGGMSCSCSSGS
Site 15S153REGGMSCSCSSGSGE
Site 16S155GGMSCSCSSGSGEAS
Site 17S156GMSCSCSSGSGEASA
Site 18S158SCSCSSGSGEASAGL
Site 19S162SSGSGEASAGLMEEA
Site 20S226LRDGQLVSQRAIPPR
Site 21S234QRAIPPRSIRGDQIA
Site 22S252GHEPGCRSIGALMAH
Site 23S273HCAGRLGSYVINGRT
Site 24Y274CAGRLGSYVINGRTK
Site 25Y294YPGNGLGYVRHVDNP
Site 26S352DRLLIFWSDRRNPHE
Site 27Y364PHEVKPAYATRYAIT
Site 28Y374RYAITVWYFDAKERA
Site 29Y387RAAAKDKYQLASGQK
Site 30S401KGVQVPVSQPPTPT_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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