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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSSK2
Full Name:
Testis-specific serine/threonine-protein kinase 2
Alias:
DGSG; DiGeorge syndrome protein G; EC 2.7.11.1; Serine/threonine protein kinase 22B; SPOGA2; ST2B; STK22B; Testis-specific kinase 2; Testis-specific serine kinase 2; TSK-2; TSSK-2
Type:
Protein-serine kinase, CAMK group, TSSK family
Mass (Da):
40939
Number AA:
358
UniProt ID:
Q96PF2
International Prot ID:
IPI00289715
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
T
V
L
R
K
K
G
Y
I
V
G
I
N
L
G
Site 2
S22
G
I
N
L
G
K
G
S
Y
A
K
V
K
S
A
Site 3
Y23
I
N
L
G
K
G
S
Y
A
K
V
K
S
A
Y
Site 4
S28
G
S
Y
A
K
V
K
S
A
Y
S
E
R
L
K
Site 5
S31
A
K
V
K
S
A
Y
S
E
R
L
K
F
N
V
Site 6
T48
K
I
I
D
R
K
K
T
P
T
D
F
V
E
R
Site 7
T50
I
D
R
K
K
T
P
T
D
F
V
E
R
F
L
Site 8
T75
N
H
G
S
I
I
K
T
Y
E
I
F
E
T
S
Site 9
Y76
H
G
S
I
I
K
T
Y
E
I
F
E
T
S
D
Site 10
T81
K
T
Y
E
I
F
E
T
S
D
G
R
I
Y
I
Site 11
Y87
E
T
S
D
G
R
I
Y
I
I
M
E
L
G
V
Site 12
S121
R
K
M
F
R
Q
L
S
S
A
V
K
Y
C
H
Site 13
S153
K
D
F
N
I
K
L
S
D
F
G
F
S
K
R
Site 14
S158
K
L
S
D
F
G
F
S
K
R
C
L
R
D
S
Site 15
S165
S
K
R
C
L
R
D
S
N
G
R
I
I
L
S
Site 16
S172
S
N
G
R
I
I
L
S
K
T
F
C
G
S
A
Site 17
T174
G
R
I
I
L
S
K
T
F
C
G
S
A
A
Y
Site 18
S189
A
A
P
E
V
L
Q
S
I
P
Y
Q
P
K
V
Site 19
Y197
I
P
Y
Q
P
K
V
Y
D
I
W
S
L
G
V
Site 20
Y207
W
S
L
G
V
I
L
Y
I
M
V
C
G
S
M
Site 21
Y216
M
V
C
G
S
M
P
Y
D
D
S
D
I
R
K
Site 22
S219
G
S
M
P
Y
D
D
S
D
I
R
K
M
L
R
Site 23
T242
F
P
R
S
K
N
L
T
C
E
C
K
D
L
I
Site 24
Y250
C
E
C
K
D
L
I
Y
R
M
L
Q
P
D
V
Site 25
S258
R
M
L
Q
P
D
V
S
Q
R
L
H
I
D
E
Site 26
S268
L
H
I
D
E
I
L
S
H
S
W
L
Q
P
P
Site 27
S282
P
K
P
K
A
T
S
S
A
S
F
K
R
E
G
Site 28
S284
P
K
A
T
S
S
A
S
F
K
R
E
G
E
G
Site 29
T301
R
A
E
C
K
L
D
T
K
T
G
L
R
P
D
Site 30
T303
E
C
K
L
D
T
K
T
G
L
R
P
D
H
R
Site 31
T319
D
H
K
L
G
A
K
T
Q
H
R
L
L
V
V
Site 32
S341
E
D
R
L
A
E
T
S
R
A
K
D
H
H
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation