PhosphoNET

           
Protein Info 
   
Short Name:  TRIB3
Full Name:  Tribbles homolog 3
Alias:  Neuronal cell death-inducible putative kinase;SINK;p65-interacting inhibitor of NF-kappa-B
Type: 
Mass (Da):  39578
Number AA:  358
UniProt ID:  Q96RU7
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12PLAAPAGSLSRKKRL
Site 2S14AAPAGSLSRKKRLEL
Site 3T27ELDDNLDTERPVQKR
Site 4S37PVQKRARSGPQPRLP
Site 5S51PPCLLPLSPPTAPDR
Site 6T60PTAPDRATAVATASR
Site 7Y71TASRLGPYVLLEPEE
Site 8Y83PEEGGRAYQALHCPT
Site 9Y94HCPTGTEYTCKVYPV
Site 10Y99TEYTCKVYPVQEALA
Site 11Y111ALAVLEPYARLPPHK
Site 12T124HKHVARPTEVLAGTQ
Site 13S146RTHGDMHSLVRSRHR
Site 14S150DMHSLVRSRHRIPEP
Site 15S206VLENLEDSCVLTGPD
Site 16T210LEDSCVLTGPDDSLW
Site 17S215VLTGPDDSLWDKHAC
Site 18Y225DKHACPAYVGPEILS
Site 19S232YVGPEILSSRASYSG
Site 20S233VGPEILSSRASYSGK
Site 21S236EILSSRASYSGKAAD
Site 22Y237ILSSRASYSGKAADV
Site 23Y259FTMLAGHYPFQDSEP
Site 24S264GHYPFQDSEPVLLFG
Site 25Y278GKIRRGAYALPAGLS
Site 26S285YALPAGLSAPARCLV
Site 27T305REPAERLTATGILLH
Site 28S327MPLAPTRSHLWEAAQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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