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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCNL2
Full Name:
Cyclin-L2
Alias:
ANIA-6B; Cyclin L2; HCLA-ISO; HLA-ISO; Paneth cell-enhanced expression; Paneth cell-enhanced expression protein; PCEE; SB138
Type:
Nuclear speck, Nucleus protein
Mass (Da):
58147
Number AA:
520
UniProt ID:
Q96S94
International Prot ID:
IPI00066458
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016607
GO:0016604
GO:0016607
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
A
A
A
G
A
P
G
S
G
G
A
P
S
G
S
Site 2
S32
S
G
G
A
P
S
G
S
Q
G
V
L
I
G
D
Site 3
T62
P
D
D
K
L
R
F
T
P
S
M
S
S
G
L
Site 4
S64
D
K
L
R
F
T
P
S
M
S
S
G
L
D
T
Site 5
T71
S
M
S
S
G
L
D
T
D
T
E
T
D
L
R
Site 6
T73
S
S
G
L
D
T
D
T
E
T
D
L
R
V
V
Site 7
T75
G
L
D
T
D
T
E
T
D
L
R
V
V
G
C
Site 8
T101
L
P
Q
V
A
M
A
T
G
Q
V
L
F
Q
R
Site 9
T112
L
F
Q
R
F
F
Y
T
K
S
F
V
K
H
S
Site 10
S119
T
K
S
F
V
K
H
S
M
E
H
V
S
M
A
Site 11
Y169
P
L
L
L
D
Q
D
Y
V
N
L
K
N
Q
I
Site 12
Y222
L
V
Q
T
S
W
N
Y
M
N
D
S
L
R
T
Site 13
T292
A
R
K
K
V
D
L
T
H
L
E
G
E
V
E
Site 14
T320
R
G
L
L
P
G
G
T
Q
V
L
D
G
T
S
Site 15
T326
G
T
Q
V
L
D
G
T
S
G
F
S
P
A
P
Site 16
S330
L
D
G
T
S
G
F
S
P
A
P
K
L
V
E
Site 17
S338
P
A
P
K
L
V
E
S
P
K
E
G
K
G
S
Site 18
S345
S
P
K
E
G
K
G
S
K
P
S
P
L
S
V
Site 19
S348
E
G
K
G
S
K
P
S
P
L
S
V
K
N
T
Site 20
S351
G
S
K
P
S
P
L
S
V
K
N
T
K
R
R
Site 21
T355
S
P
L
S
V
K
N
T
K
R
R
L
E
G
A
Site 22
S369
A
K
K
A
K
A
D
S
P
V
N
G
L
P
K
Site 23
S380
G
L
P
K
G
R
E
S
R
S
R
S
R
S
R
Site 24
S382
P
K
G
R
E
S
R
S
R
S
R
S
R
E
Q
Site 25
S384
G
R
E
S
R
S
R
S
R
S
R
E
Q
S
Y
Site 26
S386
E
S
R
S
R
S
R
S
R
E
Q
S
Y
S
R
Site 27
S390
R
S
R
S
R
E
Q
S
Y
S
R
S
P
S
R
Site 28
Y391
S
R
S
R
E
Q
S
Y
S
R
S
P
S
R
S
Site 29
S392
R
S
R
E
Q
S
Y
S
R
S
P
S
R
S
A
Site 30
S394
R
E
Q
S
Y
S
R
S
P
S
R
S
A
S
P
Site 31
S396
Q
S
Y
S
R
S
P
S
R
S
A
S
P
K
R
Site 32
S398
Y
S
R
S
P
S
R
S
A
S
P
K
R
R
K
Site 33
S400
R
S
P
S
R
S
A
S
P
K
R
R
K
S
D
Site 34
S406
A
S
P
K
R
R
K
S
D
S
G
S
T
S
G
Site 35
S408
P
K
R
R
K
S
D
S
G
S
T
S
G
G
S
Site 36
S410
R
R
K
S
D
S
G
S
T
S
G
G
S
K
S
Site 37
T411
R
K
S
D
S
G
S
T
S
G
G
S
K
S
Q
Site 38
S412
K
S
D
S
G
S
T
S
G
G
S
K
S
Q
S
Site 39
S415
S
G
S
T
S
G
G
S
K
S
Q
S
R
S
R
Site 40
S417
S
T
S
G
G
S
K
S
Q
S
R
S
R
S
R
Site 41
S419
S
G
G
S
K
S
Q
S
R
S
R
S
R
S
D
Site 42
S421
G
S
K
S
Q
S
R
S
R
S
R
S
D
S
P
Site 43
S423
K
S
Q
S
R
S
R
S
R
S
D
S
P
P
R
Site 44
S425
Q
S
R
S
R
S
R
S
D
S
P
P
R
Q
A
Site 45
S427
R
S
R
S
R
S
D
S
P
P
R
Q
A
P
R
Site 46
S435
P
P
R
Q
A
P
R
S
A
P
Y
K
G
S
E
Site 47
S441
R
S
A
P
Y
K
G
S
E
I
R
G
S
R
K
Site 48
S446
K
G
S
E
I
R
G
S
R
K
S
K
D
C
K
Site 49
S449
E
I
R
G
S
R
K
S
K
D
C
K
Y
P
Q
Site 50
Y454
R
K
S
K
D
C
K
Y
P
Q
K
P
H
K
S
Site 51
S461
Y
P
Q
K
P
H
K
S
R
S
R
S
S
S
R
Site 52
S463
Q
K
P
H
K
S
R
S
R
S
S
S
R
S
R
Site 53
S465
P
H
K
S
R
S
R
S
S
S
R
S
R
S
R
Site 54
S466
H
K
S
R
S
R
S
S
S
R
S
R
S
R
S
Site 55
S467
K
S
R
S
R
S
S
S
R
S
R
S
R
S
R
Site 56
S469
R
S
R
S
S
S
R
S
R
S
R
S
R
E
R
Site 57
S471
R
S
S
S
R
S
R
S
R
S
R
E
R
A
D
Site 58
S473
S
S
R
S
R
S
R
S
R
E
R
A
D
N
P
Site 59
Y483
R
A
D
N
P
G
K
Y
K
K
K
S
H
Y
Y
Site 60
S487
P
G
K
Y
K
K
K
S
H
Y
Y
R
D
Q
R
Site 61
Y489
K
Y
K
K
K
S
H
Y
Y
R
D
Q
R
R
E
Site 62
S498
R
D
Q
R
R
E
R
S
R
S
Y
E
R
T
G
Site 63
S500
Q
R
R
E
R
S
R
S
Y
E
R
T
G
R
R
Site 64
Y501
R
R
E
R
S
R
S
Y
E
R
T
G
R
R
Y
Site 65
T504
R
S
R
S
Y
E
R
T
G
R
R
Y
E
R
D
Site 66
Y508
Y
E
R
T
G
R
R
Y
E
R
D
H
P
G
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation