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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R9B
Full Name:
Neurabin-2
Alias:
NEB2; Neurabin-2; Neurabin-II; Neural tissue-specific F-actin binding protein II; P130; PP1bp134; PPP1R6; PPP1R9; Protein phosphatase 1, regulatory (inhibitor) subunit 9B; SPINO; Spinophilin; Spn
Type:
Protein phosphatase, regulatory subunit, Adaptor/scaffold
Mass (Da):
89192
Number AA:
815
UniProt ID:
Q96SB3
International Prot ID:
IPI00045550
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0043197
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0004864
GO:0008157
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0007050
GO:0030308
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
G
P
G
G
P
L
R
S
A
S
P
H
R
S
A
Site 2
S17
G
G
P
L
R
S
A
S
P
H
R
S
A
Y
E
Site 3
S21
R
S
A
S
P
H
R
S
A
Y
E
A
G
I
Q
Site 4
Y23
A
S
P
H
R
S
A
Y
E
A
G
I
Q
A
L
Site 5
Y50
K
G
A
H
H
K
K
Y
G
S
N
V
H
R
I
Site 6
S52
A
H
H
K
K
Y
G
S
N
V
H
R
I
K
S
Site 7
T67
M
F
L
Q
M
G
T
T
A
G
P
S
G
E
A
Site 8
S71
M
G
T
T
A
G
P
S
G
E
A
G
G
G
A
Site 9
S87
L
A
E
A
P
R
A
S
E
R
G
V
R
L
S
Site 10
S94
S
E
R
G
V
R
L
S
L
P
R
A
S
S
L
Site 11
S99
R
L
S
L
P
R
A
S
S
L
N
E
N
V
D
Site 12
S100
L
S
L
P
R
A
S
S
L
N
E
N
V
D
H
Site 13
S108
L
N
E
N
V
D
H
S
A
L
L
K
L
G
T
Site 14
S116
A
L
L
K
L
G
T
S
V
S
E
R
V
S
R
Site 15
S118
L
K
L
G
T
S
V
S
E
R
V
S
R
F
D
Site 16
S122
T
S
V
S
E
R
V
S
R
F
D
S
K
P
A
Site 17
S126
E
R
V
S
R
F
D
S
K
P
A
P
S
A
Q
Site 18
S131
F
D
S
K
P
A
P
S
A
Q
P
A
P
P
P
Site 19
S142
A
P
P
P
H
P
P
S
R
L
Q
E
T
R
K
Site 20
S154
T
R
K
L
F
E
R
S
A
P
A
A
G
G
D
Site 21
S190
V
V
V
R
F
N
G
S
T
E
A
L
D
K
L
Site 22
T191
V
V
R
F
N
G
S
T
E
A
L
D
K
L
D
Site 23
S203
K
L
D
A
D
A
V
S
P
T
V
S
Q
L
S
Site 24
T205
D
A
D
A
V
S
P
T
V
S
Q
L
S
A
V
Site 25
S218
A
V
F
E
K
A
D
S
R
T
G
L
H
R
G
Site 26
S239
A
G
V
P
Q
V
N
S
K
L
V
S
K
R
S
Site 27
S243
Q
V
N
S
K
L
V
S
K
R
S
R
V
F
Q
Site 28
S246
S
K
L
V
S
K
R
S
R
V
F
Q
P
P
P
Site 29
S260
P
P
P
P
P
A
P
S
G
D
A
P
A
E
K
Site 30
S304
K
P
V
E
V
E
E
S
G
E
S
E
A
E
S
Site 31
S307
E
V
E
E
S
G
E
S
E
A
E
S
A
P
G
Site 32
S311
S
G
E
S
E
A
E
S
A
P
G
E
V
I
Q
Site 33
T335
E
N
G
S
T
V
A
T
A
A
S
P
A
P
E
Site 34
S338
S
T
V
A
T
A
A
S
P
A
P
E
E
P
K
Site 35
S380
A
P
E
E
V
D
E
S
K
K
E
D
F
S
E
Site 36
S386
E
S
K
K
E
D
F
S
E
A
D
L
V
D
V
Site 37
S394
E
A
D
L
V
D
V
S
A
Y
S
G
L
G
E
Site 38
S403
Y
S
G
L
G
E
D
S
A
G
S
A
L
E
E
Site 39
Y423
E
E
D
G
E
P
P
Y
E
P
E
S
G
C
V
Site 40
S427
E
P
P
Y
E
P
E
S
G
C
V
E
I
P
G
Site 41
S436
C
V
E
I
P
G
L
S
E
E
E
D
P
A
P
Site 42
S450
P
S
R
K
I
H
F
S
T
A
P
I
Q
V
F
Site 43
S458
T
A
P
I
Q
V
F
S
T
Y
S
N
E
D
Y
Site 44
Y465
S
T
Y
S
N
E
D
Y
D
R
R
N
E
D
V
Site 45
S478
D
V
D
P
M
A
A
S
A
E
Y
E
L
E
K
Site 46
S501
P
V
E
L
E
K
D
S
E
G
L
G
I
S
I
Site 47
S565
V
T
Q
S
F
A
A
S
V
L
R
N
T
K
G
Site 48
T570
A
A
S
V
L
R
N
T
K
G
R
V
R
F
M
Site 49
S587
R
E
R
P
G
E
Q
S
E
V
A
Q
L
I
Q
Site 50
Y611
R
E
M
M
E
Q
R
Y
A
Q
Y
G
E
D
D
Site 51
T621
Y
G
E
D
D
E
E
T
G
E
Y
A
T
D
E
Site 52
Y624
D
D
E
E
T
G
E
Y
A
T
D
E
D
E
E
Site 53
S633
T
D
E
D
E
E
L
S
P
T
F
P
G
G
E
Site 54
T635
E
D
E
E
L
S
P
T
F
P
G
G
E
M
A
Site 55
S656
A
E
N
E
D
A
L
S
P
V
D
M
E
P
E
Site 56
S710
E
K
A
Q
L
E
Q
S
V
E
E
N
K
E
R
Site 57
T742
V
D
E
H
L
R
E
T
Q
A
Q
Y
Q
A
L
Site 58
Y746
L
R
E
T
Q
A
Q
Y
Q
A
L
E
R
K
Y
Site 59
Y753
Y
Q
A
L
E
R
K
Y
S
K
A
K
R
L
I
Site 60
S754
Q
A
L
E
R
K
Y
S
K
A
K
R
L
I
K
Site 61
Y763
A
K
R
L
I
K
D
Y
Q
Q
K
E
I
E
F
Site 62
S784
Q
R
R
V
L
E
E
S
E
L
A
R
K
E
E
Site 63
S800
D
K
L
L
D
K
I
S
E
L
E
G
N
L
Q
Site 64
T808
E
L
E
G
N
L
Q
T
L
R
N
S
N
S
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation