KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
Cdc6
Full Name:
Cell division control protein 6 homolog
Alias:
CDC18; CDC18L; CDC6 cell division cycle 6 homolog; CDC6-related protein; cell division cycle 6
Type:
Transcription protein
Mass (Da):
62720
Number AA:
560
UniProt ID:
Q99741
International Prot ID:
IPI00014575
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0017111
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0000076
GO:0051301
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
P
Q
T
R
S
Q
A
Q
A
T
I
S
Site 2
S13
S
Q
A
Q
A
T
I
S
F
P
K
R
K
L
S
Site 3
S20
S
F
P
K
R
K
L
S
R
A
L
N
K
A
K
Site 4
T37
S
D
A
K
L
E
P
T
N
V
Q
T
V
T
C
Site 5
T41
L
E
P
T
N
V
Q
T
V
T
C
S
P
R
V
Site 6
T43
P
T
N
V
Q
T
V
T
C
S
P
R
V
K
A
Site 7
S45
N
V
Q
T
V
T
C
S
P
R
V
K
A
L
P
Site 8
S54
R
V
K
A
L
P
L
S
P
R
K
R
L
G
D
Site 9
T67
G
D
D
N
L
C
N
T
P
H
L
P
P
C
S
Site 10
S74
T
P
H
L
P
P
C
S
P
P
K
Q
G
K
K
Site 11
S88
K
E
N
G
P
P
H
S
H
T
L
K
G
R
R
Site 12
T90
N
G
P
P
H
S
H
T
L
K
G
R
R
L
V
Site 13
T103
L
V
F
D
N
Q
L
T
I
K
S
P
S
K
R
Site 14
S106
D
N
Q
L
T
I
K
S
P
S
K
R
E
L
A
Site 15
S108
Q
L
T
I
K
S
P
S
K
R
E
L
A
K
V
Site 16
S122
V
H
Q
N
K
I
L
S
S
V
R
K
S
Q
E
Site 17
S123
H
Q
N
K
I
L
S
S
V
R
K
S
Q
E
I
Site 18
S127
I
L
S
S
V
R
K
S
Q
E
I
T
T
N
S
Site 19
T131
V
R
K
S
Q
E
I
T
T
N
S
E
Q
R
C
Site 20
S134
S
Q
E
I
T
T
N
S
E
Q
R
C
P
L
K
Site 21
Y157
F
K
Q
E
G
T
C
Y
Q
Q
A
K
L
V
L
Site 22
T166
Q
A
K
L
V
L
N
T
A
V
P
D
R
L
P
Site 23
Y199
G
K
K
A
G
S
L
Y
L
S
G
A
P
G
T
Site 24
S201
K
A
G
S
L
Y
L
S
G
A
P
G
T
G
K
Site 25
T228
K
E
L
K
G
F
K
T
I
M
L
N
C
M
S
Site 26
T272
R
K
L
E
K
H
M
T
A
E
K
G
P
M
I
Site 27
Y298
S
K
G
Q
D
V
L
Y
T
L
F
E
W
P
W
Site 28
Y346
Q
L
L
N
F
P
P
Y
T
R
N
Q
I
V
T
Site 29
S363
Q
D
R
L
N
Q
V
S
R
D
Q
V
L
D
N
Site 30
S381
Q
F
C
A
R
K
V
S
A
V
S
G
D
V
R
Site 31
S384
A
R
K
V
S
A
V
S
G
D
V
R
K
A
L
Site 32
S403
R
A
I
E
I
V
E
S
D
V
K
S
Q
T
I
Site 33
T409
E
S
D
V
K
S
Q
T
I
L
K
P
L
S
E
Site 34
S415
Q
T
I
L
K
P
L
S
E
C
K
S
P
S
E
Site 35
S419
K
P
L
S
E
C
K
S
P
S
E
P
L
I
P
Site 36
S421
L
S
E
C
K
S
P
S
E
P
L
I
P
K
R
Site 37
S439
I
H
I
S
Q
V
I
S
E
V
D
G
N
R
M
Site 38
T447
E
V
D
G
N
R
M
T
L
S
Q
E
G
A
Q
Site 39
S449
D
G
N
R
M
T
L
S
Q
E
G
A
Q
D
S
Site 40
S456
S
Q
E
G
A
Q
D
S
F
P
L
Q
Q
K
I
Site 41
T481
Q
L
K
I
K
E
V
T
L
G
K
L
Y
E
A
Site 42
Y486
E
V
T
L
G
K
L
Y
E
A
Y
S
K
V
C
Site 43
Y489
L
G
K
L
Y
E
A
Y
S
K
V
C
R
K
Q
Site 44
S490
G
K
L
Y
E
A
Y
S
K
V
C
R
K
Q
Q
Site 45
S510
Q
S
E
C
L
S
L
S
G
L
L
E
A
R
G
Site 46
T530
R
N
K
E
T
R
L
T
K
V
F
F
K
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation