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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NKX3-1
Full Name:
Homeobox protein Nkx-3.1
Alias:
BAPX2; NK3 homeobox 1; NKX3.1; NKX31; NKX3A
Type:
Transcription protein
Mass (Da):
26350
Number AA:
234
UniProt ID:
Q99801
International Prot ID:
IPI00018412
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
A
E
G
A
A
P
P
T
P
S
K
P
L
T
S
Site 2
S23
G
A
A
P
P
T
P
S
K
P
L
T
S
F
L
Site 3
T27
P
T
P
S
K
P
L
T
S
F
L
I
Q
D
I
Site 4
T46
A
Q
R
Q
G
G
R
T
S
S
Q
R
Q
R
D
Site 5
S47
Q
R
Q
G
G
R
T
S
S
Q
R
Q
R
D
P
Site 6
S48
R
Q
G
G
R
T
S
S
Q
R
Q
R
D
P
E
Site 7
S67
P
E
P
E
G
G
R
S
R
A
G
A
Q
N
D
Site 8
S77
G
A
Q
N
D
Q
L
S
T
G
P
R
A
A
P
Site 9
T89
A
A
P
E
E
A
E
T
L
A
E
T
E
P
E
Site 10
T93
E
A
E
T
L
A
E
T
E
P
E
R
H
L
G
Site 11
Y102
P
E
R
H
L
G
S
Y
L
L
D
S
E
N
T
Site 12
S106
L
G
S
Y
L
L
D
S
E
N
T
S
G
A
L
Site 13
S110
L
L
D
S
E
N
T
S
G
A
L
P
R
L
P
Site 14
T119
A
L
P
R
L
P
Q
T
P
K
Q
P
Q
K
R
Site 15
S127
P
K
Q
P
Q
K
R
S
R
A
A
F
S
H
T
Site 16
T134
S
R
A
A
F
S
H
T
Q
V
I
E
L
E
R
Site 17
S144
I
E
L
E
R
K
F
S
H
Q
K
Y
L
S
A
Site 18
Y148
R
K
F
S
H
Q
K
Y
L
S
A
P
E
R
A
Site 19
S150
F
S
H
Q
K
Y
L
S
A
P
E
R
A
H
L
Site 20
T166
K
N
L
K
L
T
E
T
Q
V
K
I
W
F
Q
Site 21
Y177
I
W
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
Site 22
T179
F
Q
N
R
R
Y
K
T
K
R
K
Q
L
S
S
Site 23
S185
K
T
K
R
K
Q
L
S
S
E
L
G
D
L
E
Site 24
S186
T
K
R
K
Q
L
S
S
E
L
G
D
L
E
K
Site 25
S195
L
G
D
L
E
K
H
S
S
L
P
A
L
K
E
Site 26
S196
G
D
L
E
K
H
S
S
L
P
A
L
K
E
E
Site 27
S209
E
E
A
F
S
R
A
S
L
V
S
V
Y
N
S
Site 28
S212
F
S
R
A
S
L
V
S
V
Y
N
S
Y
P
Y
Site 29
Y214
R
A
S
L
V
S
V
Y
N
S
Y
P
Y
Y
P
Site 30
S216
S
L
V
S
V
Y
N
S
Y
P
Y
Y
P
Y
L
Site 31
Y217
L
V
S
V
Y
N
S
Y
P
Y
Y
P
Y
L
Y
Site 32
Y219
S
V
Y
N
S
Y
P
Y
Y
P
Y
L
Y
C
V
Site 33
Y220
V
Y
N
S
Y
P
Y
Y
P
Y
L
Y
C
V
G
Site 34
Y222
N
S
Y
P
Y
Y
P
Y
L
Y
C
V
G
S
W
Site 35
Y224
Y
P
Y
Y
P
Y
L
Y
C
V
G
S
W
S
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation