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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SH3GL1
Full Name:
Endophilin-A2
Alias:
CNSA1; EEN; EEN fusion partner of MLL; Endophilin A2; Extra 11-19 leukemia fusion; Extra eleven-nineteen leukemia fusion gene; Fusion partner of MLL; MGC111371; SH3 domain GRB2-like 1; SH3 domain protein 2B; SH31; SH3-containing Grb-2-like 1 protein; SH3-containing GRB2-like protein 1; SH3-containing protein EEN; SH3D2B; SH3-domain GRB2-like 1; SH3-domain GRB2-like 1 (EEN); SH3G1; SH3P8
Type:
Vesicle protein
Mass (Da):
41490
Number AA:
368
UniProt ID:
Q99961
International Prot ID:
IPI00019169
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0008289
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0006897
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
A
G
L
K
K
Q
F
Y
K
A
S
Q
L
V
S
Site 2
S14
K
K
Q
F
Y
K
A
S
Q
L
V
S
E
K
V
Site 3
S18
Y
K
A
S
Q
L
V
S
E
K
V
G
G
A
E
Site 4
S44
E
K
K
V
D
V
T
S
K
A
V
T
E
V
L
Site 5
Y57
V
L
A
R
T
I
E
Y
L
Q
P
N
P
A
S
Site 6
S64
Y
L
Q
P
N
P
A
S
R
A
K
L
T
M
L
Site 7
T73
A
K
L
T
M
L
N
T
V
S
K
I
R
G
Q
Site 8
S75
L
T
M
L
N
T
V
S
K
I
R
G
Q
V
K
Site 9
Y86
G
Q
V
K
N
P
G
Y
P
Q
S
E
G
L
L
Site 10
S89
K
N
P
G
Y
P
Q
S
E
G
L
L
G
E
C
Site 11
S108
G
K
E
L
G
G
E
S
N
F
G
D
A
L
L
Site 12
S130
R
L
A
E
V
K
D
S
L
D
I
E
V
K
Q
Site 13
Y170
G
R
R
L
D
F
D
Y
K
K
K
R
Q
G
K
Site 14
T199
E
S
K
E
V
A
E
T
S
M
H
N
L
L
E
Site 15
S200
S
K
E
V
A
E
T
S
M
H
N
L
L
E
T
Site 16
S213
E
T
D
I
E
Q
V
S
Q
L
S
A
L
V
D
Site 17
Y225
L
V
D
A
Q
L
D
Y
H
R
Q
A
V
Q
I
Site 18
S248
K
R
R
M
R
E
A
S
S
R
P
K
R
E
Y
Site 19
Y255
S
S
R
P
K
R
E
Y
K
P
K
P
R
E
P
Site 20
S271
D
L
G
E
P
E
Q
S
N
G
G
F
P
C
T
Site 21
S286
T
A
P
K
I
A
A
S
S
S
F
R
S
S
D
Site 22
S287
A
P
K
I
A
A
S
S
S
F
R
S
S
D
K
Site 23
S288
P
K
I
A
A
S
S
S
F
R
S
S
D
K
P
Site 24
S291
A
A
S
S
S
F
R
S
S
D
K
P
I
R
T
Site 25
S292
A
S
S
S
F
R
S
S
D
K
P
I
R
T
P
Site 26
T298
S
S
D
K
P
I
R
T
P
S
R
S
M
P
P
Site 27
S300
D
K
P
I
R
T
P
S
R
S
M
P
P
L
D
Site 28
S302
P
I
R
T
P
S
R
S
M
P
P
L
D
Q
P
Site 29
S310
M
P
P
L
D
Q
P
S
C
K
A
L
Y
D
F
Site 30
Y315
Q
P
S
C
K
A
L
Y
D
F
E
P
E
N
D
Site 31
T336
E
G
D
V
I
T
L
T
N
Q
I
D
E
N
W
Site 32
Y344
N
Q
I
D
E
N
W
Y
E
G
M
L
D
G
Q
Site 33
S352
E
G
M
L
D
G
Q
S
G
F
F
P
L
S
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation