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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CORO1B
Full Name:
Coronin-1B
Alias:
Coronin-2
Type:
Actin binding protein
Mass (Da):
54235
Number AA:
489
UniProt ID:
Q9BR76
International Prot ID:
IPI00007058
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
F
R
K
V
V
R
Q
Site 2
S10
F
R
K
V
V
R
Q
S
K
F
R
H
V
F
G
Site 3
Y26
P
V
K
N
D
Q
C
Y
E
D
I
R
V
S
R
Site 4
T35
D
I
R
V
S
R
V
T
W
D
S
T
F
C
A
Site 5
T39
S
R
V
T
W
D
S
T
F
C
A
V
N
P
K
Site 6
S66
A
F
L
V
L
P
L
S
K
T
G
R
I
D
K
Site 7
T68
L
V
L
P
L
S
K
T
G
R
I
D
K
A
Y
Site 8
Y75
T
G
R
I
D
K
A
Y
P
T
V
C
G
H
T
Site 9
T77
R
I
D
K
A
Y
P
T
V
C
G
H
T
G
P
Site 10
S100
H
N
D
E
V
I
A
S
G
S
E
D
C
T
V
Site 11
T118
Q
I
P
E
N
G
L
T
S
P
L
T
E
P
V
Site 12
Y169
V
G
T
A
E
E
L
Y
R
L
D
S
L
H
P
Site 13
S173
E
E
L
Y
R
L
D
S
L
H
P
D
L
I
Y
Site 14
Y180
S
L
H
P
D
L
I
Y
N
V
S
W
N
H
N
Site 15
S193
H
N
G
S
L
F
C
S
A
C
K
D
K
S
V
Site 16
S199
C
S
A
C
K
D
K
S
V
R
I
I
D
P
R
Site 17
T209
I
I
D
P
R
R
G
T
L
V
A
E
R
E
K
Site 18
S243
T
T
G
F
S
R
M
S
E
R
Q
L
A
L
W
Site 19
Y283
D
P
D
T
S
V
V
Y
V
C
G
K
G
D
S
Site 20
S291
V
C
G
K
G
D
S
S
I
R
Y
F
E
I
T
Site 21
Y294
K
G
D
S
S
I
R
Y
F
E
I
T
E
E
P
Site 22
T298
S
I
R
Y
F
E
I
T
E
E
P
P
Y
I
H
Site 23
Y303
E
I
T
E
E
P
P
Y
I
H
F
L
N
T
F
Site 24
T309
P
Y
I
H
F
L
N
T
F
T
S
K
E
P
Q
Site 25
S312
H
F
L
N
T
F
T
S
K
E
P
Q
R
G
M
Site 26
S321
E
P
Q
R
G
M
G
S
M
P
K
R
G
L
E
Site 27
S330
P
K
R
G
L
E
V
S
K
C
E
I
A
R
F
Site 28
Y338
K
C
E
I
A
R
F
Y
K
L
H
E
R
K
C
Site 29
T351
K
C
E
P
I
V
M
T
V
P
R
K
S
D
L
Site 30
S356
V
M
T
V
P
R
K
S
D
L
F
Q
D
D
L
Site 31
Y364
D
L
F
Q
D
D
L
Y
P
D
T
A
G
P
E
Site 32
T367
Q
D
D
L
Y
P
D
T
A
G
P
E
A
A
L
Site 33
S381
L
E
A
E
E
W
V
S
G
R
D
A
D
P
I
Site 34
Y396
L
I
S
L
R
E
A
Y
V
P
S
K
Q
R
D
Site 35
S399
L
R
E
A
Y
V
P
S
K
Q
R
D
L
K
I
Site 36
S407
K
Q
R
D
L
K
I
S
R
R
N
V
L
S
D
Site 37
S413
I
S
R
R
N
V
L
S
D
S
R
P
A
M
A
Site 38
S415
R
R
N
V
L
S
D
S
R
P
A
M
A
P
G
Site 39
S423
R
P
A
M
A
P
G
S
S
H
L
G
A
P
A
Site 40
S424
P
A
M
A
P
G
S
S
H
L
G
A
P
A
S
Site 41
S431
S
H
L
G
A
P
A
S
T
T
T
A
A
D
A
Site 42
T439
T
T
T
A
A
D
A
T
P
S
G
S
L
A
R
Site 43
S443
A
D
A
T
P
S
G
S
L
A
R
A
G
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation