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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM48
Full Name:
Nucleoporin NDC1
Alias:
FLJ10407; HNDC1; NET3; Transmembrane protein 48
Type:
Unknown function
Mass (Da):
76305
Number AA:
674
UniProt ID:
Q9BTX1
International Prot ID:
IPI00386760
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005643
GO:0005643
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0017056
GO:0017056
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0051292
GO:0031081
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S61
P
I
Q
W
L
S
D
S
F
S
D
L
Y
S
S
Site 2
S63
Q
W
L
S
D
S
F
S
D
L
Y
S
S
Y
V
Site 3
Y66
S
D
S
F
S
D
L
Y
S
S
Y
V
I
F
Y
Site 4
S152
V
P
C
T
G
T
N
S
F
G
S
P
A
A
Q
Site 5
S155
T
G
T
N
S
F
G
S
P
A
A
Q
T
C
L
Site 6
Y184
G
Y
S
Y
S
L
L
Y
F
V
N
N
M
N
Y
Site 7
Y200
P
F
P
I
I
Q
Q
Y
K
F
L
R
F
R
R
Site 8
S311
Q
P
P
F
A
E
G
S
D
E
C
L
P
K
V
Site 9
S321
C
L
P
K
V
L
N
S
N
P
P
P
I
I
K
Site 10
S339
L
Q
D
L
M
L
L
S
Q
Y
S
P
S
R
R
Site 11
S342
L
M
L
L
S
Q
Y
S
P
S
R
R
Q
E
V
Site 12
S344
L
L
S
Q
Y
S
P
S
R
R
Q
E
V
F
S
Site 13
S351
S
R
R
Q
E
V
F
S
L
S
Q
P
G
G
H
Site 14
S353
R
Q
E
V
F
S
L
S
Q
P
G
G
H
P
H
Site 15
Y383
M
T
Q
K
L
I
L
Y
Q
E
A
A
A
T
N
Site 16
T389
L
Y
Q
E
A
A
A
T
N
G
R
V
S
S
S
Site 17
S394
A
A
T
N
G
R
V
S
S
S
Y
P
V
E
P
Site 18
S395
A
T
N
G
R
V
S
S
S
Y
P
V
E
P
K
Site 19
S396
T
N
G
R
V
S
S
S
Y
P
V
E
P
K
K
Site 20
Y397
N
G
R
V
S
S
S
Y
P
V
E
P
K
K
L
Site 21
S406
V
E
P
K
K
L
N
S
P
E
E
T
A
F
Q
Site 22
T410
K
L
N
S
P
E
E
T
A
F
Q
T
P
K
S
Site 23
T414
P
E
E
T
A
F
Q
T
P
K
S
S
Q
M
P
Site 24
S417
T
A
F
Q
T
P
K
S
S
Q
M
P
R
P
S
Site 25
S418
A
F
Q
T
P
K
S
S
Q
M
P
R
P
S
V
Site 26
S424
S
S
Q
M
P
R
P
S
V
P
P
L
V
K
T
Site 27
S432
V
P
P
L
V
K
T
S
L
F
S
S
K
L
S
Site 28
S435
L
V
K
T
S
L
F
S
S
K
L
S
T
P
D
Site 29
S436
V
K
T
S
L
F
S
S
K
L
S
T
P
D
V
Site 30
S439
S
L
F
S
S
K
L
S
T
P
D
V
V
S
P
Site 31
T440
L
F
S
S
K
L
S
T
P
D
V
V
S
P
F
Site 32
S445
L
S
T
P
D
V
V
S
P
F
G
T
P
F
G
Site 33
T449
D
V
V
S
P
F
G
T
P
F
G
S
S
V
M
Site 34
S453
P
F
G
T
P
F
G
S
S
V
M
N
R
M
A
Site 35
T467
A
G
I
F
D
V
N
T
C
Y
G
S
P
Q
S
Site 36
Y469
I
F
D
V
N
T
C
Y
G
S
P
Q
S
P
Q
Site 37
S471
D
V
N
T
C
Y
G
S
P
Q
S
P
Q
L
I
Site 38
S474
T
C
Y
G
S
P
Q
S
P
Q
L
I
R
R
G
Site 39
T486
R
R
G
P
R
L
W
T
S
A
S
D
Q
Q
M
Site 40
S487
R
G
P
R
L
W
T
S
A
S
D
Q
Q
M
T
Site 41
S489
P
R
L
W
T
S
A
S
D
Q
Q
M
T
E
F
Site 42
T494
S
A
S
D
Q
Q
M
T
E
F
S
N
P
S
P
Site 43
S497
D
Q
Q
M
T
E
F
S
N
P
S
P
S
T
S
Site 44
S500
M
T
E
F
S
N
P
S
P
S
T
S
I
S
A
Site 45
S502
E
F
S
N
P
S
P
S
T
S
I
S
A
E
G
Site 46
S504
S
N
P
S
P
S
T
S
I
S
A
E
G
K
T
Site 47
S506
P
S
P
S
T
S
I
S
A
E
G
K
T
M
R
Site 48
T511
S
I
S
A
E
G
K
T
M
R
Q
P
S
V
I
Site 49
S516
G
K
T
M
R
Q
P
S
V
I
Y
S
W
I
Q
Site 50
S520
R
Q
P
S
V
I
Y
S
W
I
Q
N
K
R
E
Site 51
Y541
S
K
R
V
L
I
M
Y
F
F
S
K
H
P
E
Site 52
S550
F
S
K
H
P
E
A
S
I
Q
A
V
F
S
D
Site 53
Y605
L
Q
E
A
V
D
K
Y
F
K
L
P
H
A
S
Site 54
S612
Y
F
K
L
P
H
A
S
S
K
P
P
R
I
S
Site 55
S613
F
K
L
P
H
A
S
S
K
P
P
R
I
S
G
Site 56
S619
S
S
K
P
P
R
I
S
G
S
L
V
D
T
S
Site 57
S621
K
P
P
R
I
S
G
S
L
V
D
T
S
Y
K
Site 58
T625
I
S
G
S
L
V
D
T
S
Y
K
T
L
R
F
Site 59
S626
S
G
S
L
V
D
T
S
Y
K
T
L
R
F
A
Site 60
Y627
G
S
L
V
D
T
S
Y
K
T
L
R
F
A
F
Site 61
T629
L
V
D
T
S
Y
K
T
L
R
F
A
F
R
A
Site 62
T646
K
T
A
I
Y
R
I
T
T
T
F
G
E
H
L
Site 63
T647
T
A
I
Y
R
I
T
T
T
F
G
E
H
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation