PhosphoNET

           
Protein Info 
   
Short Name:  CDK11
Full Name:  Cell division protein kinase 19
Alias:  BA346C16.3; CD2L6; CDC2L6; CDK8-like; CDK8-like cyclin-dependent kinase; CDK8-like cyclin-dependent kinase 11; Cell division cycle 2-like 6; Cyclin-dependent kinase (CDC2-like) 11; Death-preventing kinase; EC 2.7.11.22;; KIAA1028
Type:  EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); CMGC group; CDK family; CDK8 subfamily
Mass (Da):  56802
Number AA:  502
UniProt ID:  Q9BWU1
International Prot ID:  IPI00250316
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0004693  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006468     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y22RVEDLFEYEGCKVGR
Site 2T31GCKVGRGTYGHVYKA
Site 3Y32CKVGRGTYGHVYKAR
Site 4Y36RGTYGHVYKARRKDG
Site 5Y49DGKDEKEYALKQIEG
Site 6S60QIEGTGISMSACREI
Site 7S87ALQKVFLSHSDRKVW
Site 8S89QKVFLSHSDRKVWLL
Site 9S114IIKFHRASKANKKPM
Site 10S126KPMQLPRSMVKSLLY
Site 11S182GFARLFNSPLKPLAD
Site 12S257DQLDRIFSVMGFPAD
Site 13Y276DIRKMPEYPTLQKDF
Site 14T286LQKDFRRTTYANSSL
Site 15T287QKDFRRTTYANSSLI
Site 16Y288KDFRRTTYANSSLIK
Site 17Y296ANSSLIKYMEKHKVK
Site 18S306KHKVKPDSKVFLLLQ
Site 19T321KLLTMDPTKRITSEQ
Site 20T325MDPTKRITSEQALQD
Site 21S326DPTKRITSEQALQDP
Site 22Y334EQALQDPYFQEDPLP
Site 23Y353FAGCQIPYPKREFLN
Site 24S426TGAGLQHSQDSSLNQ
Site 25S430LQHSQDSSLNQVPPN
Site 26S445KKPRLGPSGANSGGP
Site 27S449LGPSGANSGGPVMPS
Site 28S456SGGPVMPSDYQHSSS
Site 29Y458GPVMPSDYQHSSSRL
Site 30S461MPSDYQHSSSRLNYQ
Site 31S462PSDYQHSSSRLNYQS
Site 32S463SDYQHSSSRLNYQSS
Site 33Y467HSSSRLNYQSSVQGS
Site 34S469SSRLNYQSSVQGSSQ
Site 35S470SRLNYQSSVQGSSQS
Site 36S474YQSSVQGSSQSQSTL
Site 37S475QSSVQGSSQSQSTLG
Site 38S477SVQGSSQSQSTLGYS
Site 39S479QGSSQSQSTLGYSSS
Site 40T480GSSQSQSTLGYSSSS
Site 41Y483QSQSTLGYSSSSQQS
Site 42S484SQSTLGYSSSSQQSS
Site 43S485QSTLGYSSSSQQSSQ
Site 44S486STLGYSSSSQQSSQY
Site 45S487TLGYSSSSQQSSQYH
Site 46S490YSSSSQQSSQYHPSH
Site 47S491SSSSQQSSQYHPSHQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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