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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSSK1
Full Name:
Testis-specific serine/threonine-protein kinase 1
Alias:
EC 2.7.11.1; FKSG81; Serine/threonine protein kinase 22A; Serine/threonine protein kinase FKSG81; SPOGA1; SPOGA4; ST2A; STK22A; STK22D; Testis-specific kinase 1; Testis-specific serine kinase 1; TSK-1; TSSK-1; TSSK7P
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1;
CAMK
group; TSSK family
Mass (Da):
41618
Number AA:
367
UniProt ID:
Q9BXA7
International Prot ID:
IPI00012465
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
A
V
L
K
R
R
G
Y
L
L
G
I
N
L
G
Site 2
S22
G
I
N
L
G
E
G
S
Y
A
K
V
K
S
A
Site 3
Y23
I
N
L
G
E
G
S
Y
A
K
V
K
S
A
Y
Site 4
S28
G
S
Y
A
K
V
K
S
A
Y
S
E
R
L
K
Site 5
S31
A
K
V
K
S
A
Y
S
E
R
L
K
F
N
V
Site 6
T75
N
H
C
S
I
I
K
T
Y
E
I
F
E
T
S
Site 7
Y76
H
C
S
I
I
K
T
Y
E
I
F
E
T
S
H
Site 8
T81
K
T
Y
E
I
F
E
T
S
H
G
K
V
Y
I
Site 9
T104
D
L
L
E
L
I
K
T
R
G
A
L
H
E
D
Site 10
S153
K
D
F
N
I
K
L
S
D
F
S
F
S
K
R
Site 11
S156
N
I
K
L
S
D
F
S
F
S
K
R
C
L
R
Site 12
S158
K
L
S
D
F
S
F
S
K
R
C
L
R
D
D
Site 13
S166
K
R
C
L
R
D
D
S
G
R
M
A
L
S
K
Site 14
S172
D
S
G
R
M
A
L
S
K
T
F
C
G
S
P
Site 15
T174
G
R
M
A
L
S
K
T
F
C
G
S
P
A
Y
Site 16
S178
L
S
K
T
F
C
G
S
P
A
Y
A
A
P
E
Site 17
Y192
E
V
L
Q
G
I
P
Y
Q
P
K
V
Y
D
I
Site 18
Y197
I
P
Y
Q
P
K
V
Y
D
I
W
S
L
G
V
Site 19
Y207
W
S
L
G
V
I
L
Y
I
M
V
C
G
S
M
Site 20
Y216
M
V
C
G
S
M
P
Y
D
D
S
N
I
K
K
Site 21
S219
G
S
M
P
Y
D
D
S
N
I
K
K
M
L
R
Site 22
S238
H
R
V
N
F
P
R
S
K
H
L
T
G
E
C
Site 23
T242
F
P
R
S
K
H
L
T
G
E
C
K
D
L
I
Site 24
Y250
G
E
C
K
D
L
I
Y
H
M
L
Q
P
D
V
Site 25
S279
M
Q
P
K
A
R
G
S
P
S
V
A
I
N
K
Site 26
S281
P
K
A
R
G
S
P
S
V
A
I
N
K
E
G
Site 27
S290
A
I
N
K
E
G
E
S
S
R
G
T
E
P
L
Site 28
S291
I
N
K
E
G
E
S
S
R
G
T
E
P
L
W
Site 29
T294
E
G
E
S
S
R
G
T
E
P
L
W
T
P
E
Site 30
T299
R
G
T
E
P
L
W
T
P
E
P
G
S
D
K
Site 31
S304
L
W
T
P
E
P
G
S
D
K
K
S
A
T
K
Site 32
S308
E
P
G
S
D
K
K
S
A
T
K
L
E
P
E
Site 33
S336
E
G
T
A
M
Q
M
S
R
Q
S
E
I
L
G
Site 34
S339
A
M
Q
M
S
R
Q
S
E
I
L
G
F
P
S
Site 35
S346
S
E
I
L
G
F
P
S
K
P
S
T
M
E
T
Site 36
S349
L
G
F
P
S
K
P
S
T
M
E
T
E
E
G
Site 37
T350
G
F
P
S
K
P
S
T
M
E
T
E
E
G
P
Site 38
T353
S
K
P
S
T
M
E
T
E
E
G
P
P
Q
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation