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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MKI67IP
Full Name:
MKI67 FHA domain-interacting nucleolar phosphoprotein
Alias:
MK67I; MKI67 (FHA domain) interacting nucleolar phosphoprotein; NIFK; Nopp34; Nucleolar phosphoprotein Nopp34; Nucleolar protein interacting with the FHA domain of pKI-67; Nucleolar protein NIFK; RNA binding protein
Type:
RNA binding protein
Mass (Da):
34222
Number AA:
293
UniProt ID:
Q9BYG3
International Prot ID:
IPI00154590
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000794
GO:0005737
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006461
GO:0016072
GO:0009303
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
G
P
A
G
P
I
L
S
L
N
P
Q
E
D
V
Site 2
T34
A
Q
V
R
K
R
I
T
Q
R
K
K
Q
E
Q
Site 3
T43
R
K
K
Q
E
Q
L
T
P
G
V
V
Y
V
R
Site 4
Y48
Q
L
T
P
G
V
V
Y
V
R
H
L
P
N
L
Site 5
Y64
D
E
T
Q
I
F
S
Y
F
S
Q
F
G
T
V
Site 6
S66
T
Q
I
F
S
Y
F
S
Q
F
G
T
V
T
R
Site 7
T70
S
Y
F
S
Q
F
G
T
V
T
R
F
R
L
S
Site 8
T72
F
S
Q
F
G
T
V
T
R
F
R
L
S
R
S
Site 9
S77
T
V
T
R
F
R
L
S
R
S
K
R
T
G
N
Site 10
S79
T
R
F
R
L
S
R
S
K
R
T
G
N
S
K
Site 11
Y88
R
T
G
N
S
K
G
Y
A
F
V
E
F
E
S
Site 12
S142
N
I
P
F
K
Q
P
S
Y
P
S
V
K
R
Y
Site 13
Y143
I
P
F
K
Q
P
S
Y
P
S
V
K
R
Y
N
Site 14
S145
F
K
Q
P
S
Y
P
S
V
K
R
Y
N
R
N
Site 15
Y149
S
Y
P
S
V
K
R
Y
N
R
N
R
T
L
T
Site 16
T154
K
R
Y
N
R
N
R
T
L
T
Q
K
L
R
M
Site 17
T156
Y
N
R
N
R
T
L
T
Q
K
L
R
M
E
E
Site 18
Y183
L
A
K
K
G
I
D
Y
D
F
P
S
L
I
L
Site 19
S187
G
I
D
Y
D
F
P
S
L
I
L
Q
K
T
E
Site 20
T193
P
S
L
I
L
Q
K
T
E
S
I
S
K
T
N
Site 21
S195
L
I
L
Q
K
T
E
S
I
S
K
T
N
R
Q
Site 22
T199
K
T
E
S
I
S
K
T
N
R
Q
T
S
T
K
Site 23
T203
I
S
K
T
N
R
Q
T
S
T
K
G
Q
V
L
Site 24
S204
S
K
T
N
R
Q
T
S
T
K
G
Q
V
L
R
Site 25
S218
R
K
K
K
K
K
V
S
G
T
L
D
T
P
E
Site 26
T220
K
K
K
K
V
S
G
T
L
D
T
P
E
K
T
Site 27
T223
K
V
S
G
T
L
D
T
P
E
K
T
V
D
S
Site 28
T227
T
L
D
T
P
E
K
T
V
D
S
Q
G
P
T
Site 29
S230
T
P
E
K
T
V
D
S
Q
G
P
T
P
V
C
Site 30
T234
T
V
D
S
Q
G
P
T
P
V
C
T
P
T
F
Site 31
T238
Q
G
P
T
P
V
C
T
P
T
F
L
E
R
R
Site 32
T240
P
T
P
V
C
T
P
T
F
L
E
R
R
K
S
Site 33
S247
T
F
L
E
R
R
K
S
Q
V
A
E
L
N
D
Site 34
T277
V
K
E
E
I
Q
E
T
Q
T
P
T
H
S
R
Site 35
T279
E
E
I
Q
E
T
Q
T
P
T
H
S
R
K
K
Site 36
S290
S
R
K
K
R
R
R
S
S
N
Q
_
_
_
_
Site 37
S291
R
K
K
R
R
R
S
S
N
Q
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation