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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BACH2
Full Name:
Transcription regulator protein BACH2
Alias:
BTB and CNC homologue 2
Type:
Transcription protein
Mass (Da):
92537
Number AA:
841
UniProt ID:
Q9BYV9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0046983
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
V
D
E
K
P
D
S
P
M
Y
V
Y
E
S
Site 2
Y12
E
K
P
D
S
P
M
Y
V
Y
E
S
T
V
H
Site 3
Y14
P
D
S
P
M
Y
V
Y
E
S
T
V
H
C
T
Site 4
T40
K
D
I
L
C
D
V
T
L
I
V
E
R
K
E
Site 5
S77
T
K
N
D
L
V
V
S
L
P
E
E
V
T
A
Site 6
T131
S
C
F
S
F
L
Q
T
Q
L
L
N
S
E
D
Site 7
S159
P
H
E
D
C
E
N
S
A
G
E
E
E
D
E
Site 8
T170
E
E
D
E
E
E
E
T
M
D
S
E
T
A
K
Site 9
S173
E
E
E
E
T
M
D
S
E
T
A
K
M
A
C
Site 10
T214
L
P
E
P
D
V
P
T
D
T
K
E
S
S
E
Site 11
T216
E
P
D
V
P
T
D
T
K
E
S
S
E
K
D
Site 12
S220
P
T
D
T
K
E
S
S
E
K
D
A
L
T
Q
Site 13
T226
S
S
E
K
D
A
L
T
Q
Y
P
R
Y
K
K
Site 14
Y228
E
K
D
A
L
T
Q
Y
P
R
Y
K
K
Y
Q
Site 15
Y231
A
L
T
Q
Y
P
R
Y
K
K
Y
Q
L
A
C
Site 16
Y234
Q
Y
P
R
Y
K
K
Y
Q
L
A
C
T
K
N
Site 17
Y243
L
A
C
T
K
N
V
Y
N
A
S
S
H
S
T
Site 18
S246
T
K
N
V
Y
N
A
S
S
H
S
T
S
G
F
Site 19
S247
K
N
V
Y
N
A
S
S
H
S
T
S
G
F
A
Site 20
S249
V
Y
N
A
S
S
H
S
T
S
G
F
A
S
T
Site 21
T250
Y
N
A
S
S
H
S
T
S
G
F
A
S
T
F
Site 22
S251
N
A
S
S
H
S
T
S
G
F
A
S
T
F
R
Site 23
S255
H
S
T
S
G
F
A
S
T
F
R
E
D
N
S
Site 24
T256
S
T
S
G
F
A
S
T
F
R
E
D
N
S
S
Site 25
S262
S
T
F
R
E
D
N
S
S
N
S
L
K
P
G
Site 26
S263
T
F
R
E
D
N
S
S
N
S
L
K
P
G
L
Site 27
S265
R
E
D
N
S
S
N
S
L
K
P
G
L
A
R
Site 28
S277
L
A
R
G
Q
I
K
S
E
P
P
S
E
E
N
Site 29
S281
Q
I
K
S
E
P
P
S
E
E
N
E
E
E
S
Site 30
S288
S
E
E
N
E
E
E
S
I
T
L
C
L
S
G
Site 31
T290
E
N
E
E
E
S
I
T
L
C
L
S
G
D
E
Site 32
S294
E
S
I
T
L
C
L
S
G
D
E
P
D
A
K
Site 33
S315
E
M
D
R
K
Q
P
S
P
A
P
T
P
T
A
Site 34
T319
K
Q
P
S
P
A
P
T
P
T
A
P
A
G
A
Site 35
S334
A
C
L
E
R
S
R
S
V
A
S
P
S
C
L
Site 36
S337
E
R
S
R
S
V
A
S
P
S
C
L
R
S
L
Site 37
S339
S
R
S
V
A
S
P
S
C
L
R
S
L
F
S
Site 38
S343
A
S
P
S
C
L
R
S
L
F
S
I
T
K
S
Site 39
S354
I
T
K
S
V
E
L
S
G
L
P
S
T
S
Q
Site 40
S358
V
E
L
S
G
L
P
S
T
S
Q
Q
H
F
A
Site 41
S360
L
S
G
L
P
S
T
S
Q
Q
H
F
A
R
S
Site 42
S367
S
Q
Q
H
F
A
R
S
P
A
C
P
F
D
K
Site 43
T383
I
T
Q
G
D
L
K
T
D
Y
T
P
F
T
G
Site 44
Y385
Q
G
D
L
K
T
D
Y
T
P
F
T
G
N
Y
Site 45
T386
G
D
L
K
T
D
Y
T
P
F
T
G
N
Y
G
Site 46
T389
K
T
D
Y
T
P
F
T
G
N
Y
G
Q
P
H
Site 47
Y392
Y
T
P
F
T
G
N
Y
G
Q
P
H
V
G
Q
Site 48
S409
V
S
N
F
T
M
G
S
P
L
R
G
P
G
L
Site 49
S430
E
G
E
L
D
R
R
S
V
I
F
S
S
S
A
Site 50
S434
D
R
R
S
V
I
F
S
S
S
A
C
D
Q
V
Site 51
S436
R
S
V
I
F
S
S
S
A
C
D
Q
V
S
T
Site 52
S442
S
S
A
C
D
Q
V
S
T
S
V
H
S
Y
S
Site 53
T443
S
A
C
D
Q
V
S
T
S
V
H
S
Y
S
G
Site 54
S444
A
C
D
Q
V
S
T
S
V
H
S
Y
S
G
V
Site 55
S447
Q
V
S
T
S
V
H
S
Y
S
G
V
S
S
L
Site 56
Y448
V
S
T
S
V
H
S
Y
S
G
V
S
S
L
D
Site 57
S449
S
T
S
V
H
S
Y
S
G
V
S
S
L
D
K
Site 58
S453
H
S
Y
S
G
V
S
S
L
D
K
D
L
S
E
Site 59
S459
S
S
L
D
K
D
L
S
E
P
V
P
K
G
L
Site 60
S473
L
W
V
G
A
G
Q
S
L
P
S
S
Q
A
Y
Site 61
S476
G
A
G
Q
S
L
P
S
S
Q
A
Y
S
H
G
Site 62
S477
A
G
Q
S
L
P
S
S
Q
A
Y
S
H
G
G
Site 63
Y480
S
L
P
S
S
Q
A
Y
S
H
G
G
L
M
A
Site 64
S481
L
P
S
S
Q
A
Y
S
H
G
G
L
M
A
D
Site 65
T498
P
G
R
M
R
P
N
T
S
C
P
V
P
I
K
Site 66
S499
G
R
M
R
P
N
T
S
C
P
V
P
I
K
V
Site 67
S510
P
I
K
V
C
P
R
S
P
P
L
E
T
R
T
Site 68
T515
P
R
S
P
P
L
E
T
R
T
R
T
S
S
S
Site 69
T517
S
P
P
L
E
T
R
T
R
T
S
S
S
C
S
Site 70
T519
P
L
E
T
R
T
R
T
S
S
S
C
S
S
Y
Site 71
S520
L
E
T
R
T
R
T
S
S
S
C
S
S
Y
S
Site 72
S521
E
T
R
T
R
T
S
S
S
C
S
S
Y
S
Y
Site 73
S522
T
R
T
R
T
S
S
S
C
S
S
Y
S
Y
A
Site 74
S524
T
R
T
S
S
S
C
S
S
Y
S
Y
A
E
D
Site 75
S525
R
T
S
S
S
C
S
S
Y
S
Y
A
E
D
G
Site 76
Y526
T
S
S
S
C
S
S
Y
S
Y
A
E
D
G
S
Site 77
S527
S
S
S
C
S
S
Y
S
Y
A
E
D
G
S
G
Site 78
Y528
S
S
C
S
S
Y
S
Y
A
E
D
G
S
G
G
Site 79
S533
Y
S
Y
A
E
D
G
S
G
G
S
P
C
S
L
Site 80
S536
A
E
D
G
S
G
G
S
P
C
S
L
P
L
C
Site 81
S546
S
L
P
L
C
E
F
S
S
S
P
C
S
Q
G
Site 82
S547
L
P
L
C
E
F
S
S
S
P
C
S
Q
G
A
Site 83
S548
P
L
C
E
F
S
S
S
P
C
S
Q
G
A
R
Site 84
S551
E
F
S
S
S
P
C
S
Q
G
A
R
F
L
A
Site 85
T559
Q
G
A
R
F
L
A
T
E
H
Q
E
P
G
L
Site 86
Y572
G
L
M
G
D
G
M
Y
N
Q
V
R
P
Q
I
Site 87
S584
P
Q
I
K
C
E
Q
S
Y
G
T
N
S
S
D
Site 88
Y585
Q
I
K
C
E
Q
S
Y
G
T
N
S
S
D
E
Site 89
S589
E
Q
S
Y
G
T
N
S
S
D
E
S
G
S
F
Site 90
S590
Q
S
Y
G
T
N
S
S
D
E
S
G
S
F
S
Site 91
S593
G
T
N
S
S
D
E
S
G
S
F
S
E
A
D
Site 92
S595
N
S
S
D
E
S
G
S
F
S
E
A
D
S
E
Site 93
S597
S
D
E
S
G
S
F
S
E
A
D
S
E
S
C
Site 94
S601
G
S
F
S
E
A
D
S
E
S
C
P
V
Q
D
Site 95
S603
F
S
E
A
D
S
E
S
C
P
V
Q
D
R
G
Site 96
T623
P
F
P
V
D
Q
I
T
D
L
P
R
N
D
F
Site 97
S654
I
H
D
V
R
R
R
S
K
N
R
I
A
A
Q
Site 98
S690
C
E
K
E
K
L
L
S
E
R
N
Q
L
K
A
Site 99
S710
L
D
N
F
S
C
L
S
Q
E
V
C
R
D
I
Site 100
S719
E
V
C
R
D
I
Q
S
P
E
Q
I
Q
A
L
Site 101
Y729
Q
I
Q
A
L
H
R
Y
C
P
V
L
R
P
M
Site 102
T740
L
R
P
M
D
L
P
T
A
S
S
I
N
P
A
Site 103
S742
P
M
D
L
P
T
A
S
S
I
N
P
A
P
L
Site 104
S758
A
E
Q
N
I
A
A
S
Q
C
A
V
G
E
N
Site 105
S784
P
G
P
P
W
A
P
S
N
T
S
E
N
C
T
Site 106
S787
P
W
A
P
S
N
T
S
E
N
C
T
S
G
R
Site 107
T791
S
N
T
S
E
N
C
T
S
G
R
R
L
E
G
Site 108
S792
N
T
S
E
N
C
T
S
G
R
R
L
E
G
T
Site 109
T799
S
G
R
R
L
E
G
T
D
P
G
T
F
S
E
Site 110
T803
L
E
G
T
D
P
G
T
F
S
E
R
G
P
P
Site 111
S805
G
T
D
P
G
T
F
S
E
R
G
P
P
L
E
Site 112
S815
G
P
P
L
E
P
R
S
Q
T
V
T
V
D
F
Site 113
T817
P
L
E
P
R
S
Q
T
V
T
V
D
F
C
Q
Site 114
T819
E
P
R
S
Q
T
V
T
V
D
F
C
Q
E
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation