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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCAMKL3
Full Name:
Serine/threonine-protein kinase DCLK3
Alias:
DCLK3; Doublecortin-like kinase 3; EC 2.7.11.1; KIAA1765
Type:
Protein-serine kinase, CAMK group, DCAMKL family
Mass (Da):
73814
Number AA:
608
UniProt ID:
Q9C098
International Prot ID:
IPI00028196
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
Q
V
A
V
E
E
L
Y
P
N
K
A
R
A
L
Site 2
T27
P
N
K
A
R
A
L
T
L
A
Q
H
S
R
A
Site 3
S32
A
L
T
L
A
Q
H
S
R
A
P
S
P
R
L
Site 4
S36
A
Q
H
S
R
A
P
S
P
R
L
R
S
R
L
Site 5
S41
A
P
S
P
R
L
R
S
R
L
F
S
K
A
L
Site 6
S45
R
L
R
S
R
L
F
S
K
A
L
K
G
D
H
Site 7
T57
G
D
H
R
C
G
E
T
E
T
P
K
S
C
S
Site 8
T59
H
R
C
G
E
T
E
T
P
K
S
C
S
E
V
Site 9
S62
G
E
T
E
T
P
K
S
C
S
E
V
A
G
C
Site 10
S64
T
E
T
P
K
S
C
S
E
V
A
G
C
K
A
Site 11
T91
S
L
D
D
R
A
R
T
Q
K
K
W
G
R
G
Site 12
S105
G
K
W
E
P
E
P
S
S
K
P
P
R
E
A
Site 13
S106
K
W
E
P
E
P
S
S
K
P
P
R
E
A
T
Site 14
T113
S
K
P
P
R
E
A
T
L
E
E
R
H
A
R
Site 15
S151
R
E
R
E
L
Q
Q
S
L
E
R
E
R
L
S
Site 16
S158
S
L
E
R
E
R
L
S
L
G
T
S
E
L
D
Site 17
S162
E
R
L
S
L
G
T
S
E
L
D
M
G
K
G
Site 18
Y172
D
M
G
K
G
P
M
Y
D
V
E
K
L
V
R
Site 19
S182
E
K
L
V
R
T
R
S
C
R
R
S
P
E
A
Site 20
S186
R
T
R
S
C
R
R
S
P
E
A
N
P
A
S
Site 21
S193
S
P
E
A
N
P
A
S
G
E
E
G
W
K
G
Site 22
S202
E
E
G
W
K
G
D
S
H
R
S
S
P
R
N
Site 23
S205
W
K
G
D
S
H
R
S
S
P
R
N
P
T
Q
Site 24
S206
K
G
D
S
H
R
S
S
P
R
N
P
T
Q
E
Site 25
T211
R
S
S
P
R
N
P
T
Q
E
L
R
R
P
S
Site 26
S218
T
Q
E
L
R
R
P
S
K
S
M
D
K
K
E
Site 27
S220
E
L
R
R
P
S
K
S
M
D
K
K
E
D
R
Site 28
S234
R
G
P
E
D
Q
E
S
H
A
Q
G
A
A
K
Site 29
T264
L
R
E
V
K
K
D
T
R
P
M
S
R
S
K
Site 30
S268
K
K
D
T
R
P
M
S
R
S
K
H
G
G
W
Site 31
S270
D
T
R
P
M
S
R
S
K
H
G
G
W
L
L
Site 32
T290
G
F
E
K
L
R
R
T
R
G
E
E
K
E
A
Site 33
S306
K
E
K
K
P
C
M
S
G
G
R
R
M
T
L
Site 34
T312
M
S
G
G
R
R
M
T
L
R
D
D
Q
P
A
Site 35
S338
E
N
K
P
E
R
P
S
G
R
K
P
R
P
M
Site 36
T358
N
V
E
K
H
Y
E
T
G
R
V
I
G
D
G
Site 37
T378
K
E
C
R
H
R
E
T
R
Q
A
Y
A
M
K
Site 38
Y382
H
R
E
T
R
Q
A
Y
A
M
K
I
I
D
K
Site 39
S390
A
M
K
I
I
D
K
S
R
L
K
G
K
E
D
Site 40
S401
G
K
E
D
M
V
D
S
E
I
L
I
I
Q
S
Site 41
T423
K
L
H
E
V
Y
E
T
D
M
E
I
Y
L
I
Site 42
S492
V
Q
R
N
E
D
K
S
T
T
L
K
L
A
D
Site 43
T493
Q
R
N
E
D
K
S
T
T
L
K
L
A
D
F
Site 44
S526
Y
V
A
P
E
I
L
S
E
K
G
Y
G
L
E
Site 45
Y530
E
I
L
S
E
K
G
Y
G
L
E
V
D
M
W
Site 46
S555
C
G
F
P
P
F
R
S
P
E
R
D
Q
D
E
Site 47
Y578
H
F
E
F
L
P
P
Y
W
D
N
I
S
D
A
Site 48
S583
P
P
Y
W
D
N
I
S
D
A
A
K
D
L
V
Site 49
S591
D
A
A
K
D
L
V
S
R
L
L
V
V
D
P
Site 50
T603
V
D
P
K
K
R
Y
T
A
H
Q
V
L
Q
H
Site 51
T621
E
T
A
G
K
T
N
T
V
K
R
Q
K
Q
V
Site 52
S629
V
K
R
Q
K
Q
V
S
P
S
S
E
G
H
F
Site 53
S631
R
Q
K
Q
V
S
P
S
S
E
G
H
F
R
S
Site 54
S632
Q
K
Q
V
S
P
S
S
E
G
H
F
R
S
Q
Site 55
S638
S
S
E
G
H
F
R
S
Q
H
K
R
V
V
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation