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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cdt1
Full Name:
DNA replication factor Cdt1
Alias:
chromatin licensing and DNA replication factor 1; DNA replication factor; DUP; HCDT1; MMCDT1; RIS2
Type:
DNA replication protein
Mass (Da):
60443
Number AA:
546
UniProt ID:
Q9H211
International Prot ID:
IPI00096899
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
GO:0005657
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0000076
GO:0007049
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
E
Q
R
R
V
T
D
F
F
A
R
R
R
Site 2
T29
P
P
K
L
A
C
R
T
P
S
P
A
R
P
A
Site 3
S31
K
L
A
C
R
T
P
S
P
A
R
P
A
L
R
Site 4
S42
P
A
L
R
A
P
A
S
A
T
S
G
S
R
K
Site 5
T44
L
R
A
P
A
S
A
T
S
G
S
R
K
R
A
Site 6
S45
R
A
P
A
S
A
T
S
G
S
R
K
R
A
R
Site 7
S73
A
R
R
R
L
R
L
S
V
D
E
V
S
S
P
Site 8
S78
R
L
S
V
D
E
V
S
S
P
S
T
P
E
A
Site 9
S79
L
S
V
D
E
V
S
S
P
S
T
P
E
A
P
Site 10
T82
D
E
V
S
S
P
S
T
P
E
A
P
D
I
P
Site 11
S93
P
D
I
P
A
C
P
S
P
G
Q
K
I
K
K
Site 12
S101
P
G
Q
K
I
K
K
S
T
P
A
A
G
Q
P
Site 13
T102
G
Q
K
I
K
K
S
T
P
A
A
G
Q
P
P
Site 14
T119
T
S
A
Q
D
Q
D
T
I
S
E
L
A
S
C
Site 15
S121
A
Q
D
Q
D
T
I
S
E
L
A
S
C
L
Q
Site 16
S125
D
T
I
S
E
L
A
S
C
L
Q
R
A
R
E
Site 17
S143
R
V
R
A
L
K
A
S
A
Q
D
A
G
E
S
Site 18
T152
Q
D
A
G
E
S
C
T
P
E
A
E
G
R
P
Site 19
Y170
C
G
E
K
A
P
A
Y
Q
R
F
H
A
L
A
Site 20
S211
V
G
M
L
H
N
R
S
E
T
P
T
F
A
K
Site 21
T213
M
L
H
N
R
S
E
T
P
T
F
A
K
V
Q
Site 22
T215
H
N
R
S
E
T
P
T
F
A
K
V
Q
R
G
Site 23
T241
R
N
V
G
Q
I
K
T
V
Y
P
A
S
Y
R
Site 24
Y243
V
G
Q
I
K
T
V
Y
P
A
S
Y
R
F
R
Site 25
S246
I
K
T
V
Y
P
A
S
Y
R
F
R
Q
E
R
Site 26
S254
Y
R
F
R
Q
E
R
S
V
P
T
F
K
D
G
Site 27
T257
R
Q
E
R
S
V
P
T
F
K
D
G
T
R
R
Site 28
S265
F
K
D
G
T
R
R
S
D
Y
Q
L
T
I
E
Site 29
Y267
D
G
T
R
R
S
D
Y
Q
L
T
I
E
P
L
Site 30
T270
R
R
S
D
Y
Q
L
T
I
E
P
L
L
E
Q
Site 31
T287
D
G
A
A
P
Q
L
T
A
S
R
L
L
Q
R
Site 32
S299
L
Q
R
R
Q
I
F
S
Q
K
L
V
E
H
V
Site 33
S318
K
A
F
L
A
S
L
S
P
A
M
V
V
P
E
Site 34
T359
P
A
T
E
K
L
T
T
A
Q
E
V
L
A
R
Site 35
S372
A
R
A
R
N
L
I
S
P
R
M
E
K
A
L
Site 36
S380
P
R
M
E
K
A
L
S
Q
L
A
L
R
S
A
Site 37
S386
L
S
Q
L
A
L
R
S
A
A
P
S
S
P
G
Site 38
S390
A
L
R
S
A
A
P
S
S
P
G
S
P
R
P
Site 39
S391
L
R
S
A
A
P
S
S
P
G
S
P
R
P
A
Site 40
S394
A
A
P
S
S
P
G
S
P
R
P
A
L
P
A
Site 41
T402
P
R
P
A
L
P
A
T
P
P
A
T
P
P
A
Site 42
T406
L
P
A
T
P
P
A
T
P
P
A
A
S
P
S
Site 43
S411
P
A
T
P
P
A
A
S
P
S
A
L
K
G
V
Site 44
S413
T
P
P
A
A
S
P
S
A
L
K
G
V
S
Q
Site 45
T439
Q
K
Q
L
A
Q
M
T
R
C
P
E
Q
E
Q
Site 46
S463
E
L
A
R
V
L
R
S
V
F
V
S
E
R
K
Site 47
S474
S
E
R
K
P
A
L
S
M
E
V
A
C
A
R
Site 48
S491
G
S
C
C
T
I
M
S
P
G
E
M
E
K
H
Site 49
S511
E
L
L
P
D
W
L
S
L
H
R
I
R
T
D
Site 50
T517
L
S
L
H
R
I
R
T
D
T
Y
V
K
L
D
Site 51
T519
L
H
R
I
R
T
D
T
Y
V
K
L
D
K
A
Site 52
Y520
H
R
I
R
T
D
T
Y
V
K
L
D
K
A
A
Site 53
T540
T
A
R
L
A
H
Q
T
R
A
E
E
G
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation