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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NHEJ1
Full Name:
Non-homologous end-joining factor 1
Alias:
Cernunnos; FLJ12610; nonhomologous end-joining factor 1; XLF
Type:
DNA repair
Mass (Da):
33340
Number AA:
UniProt ID:
Q9H9Q4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0030183
GO:0030217
GO:0007417
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T51
V
W
H
E
Q
V
D
T
S
V
V
S
Q
R
A
Site 2
S52
W
H
E
Q
V
D
T
S
V
V
S
Q
R
A
K
Site 3
S55
Q
V
D
T
S
V
V
S
Q
R
A
K
E
L
N
Site 4
T66
K
E
L
N
K
R
L
T
A
P
P
A
A
F
L
Site 5
S91
L
K
D
A
A
H
P
S
E
A
T
F
S
C
D
Site 6
S113
L
R
V
R
S
E
L
S
G
L
P
F
Y
W
N
Site 7
S132
L
A
S
P
S
L
V
S
Q
H
L
I
R
P
L
Site 8
Y167
K
D
L
E
I
Q
D
Y
Q
E
S
G
A
T
L
Site 9
T173
D
Y
Q
E
S
G
A
T
L
I
R
D
R
L
K
Site 10
T181
L
I
R
D
R
L
K
T
E
P
F
E
E
N
S
Site 11
S188
T
E
P
F
E
E
N
S
F
L
E
Q
F
M
I
Site 12
S203
E
K
L
P
E
A
C
S
I
G
D
G
K
P
F
Site 13
T223
D
L
Y
M
A
V
T
T
Q
E
V
Q
V
G
Q
Site 14
T240
Q
G
A
G
D
P
H
T
S
N
S
A
S
L
Q
Site 15
S241
G
A
G
D
P
H
T
S
N
S
A
S
L
Q
G
Site 16
S243
G
D
P
H
T
S
N
S
A
S
L
Q
G
I
D
Site 17
S245
P
H
T
S
N
S
A
S
L
Q
G
I
D
S
Q
Site 18
S251
A
S
L
Q
G
I
D
S
Q
C
V
N
Q
P
E
Site 19
S262
N
Q
P
E
Q
L
V
S
S
A
P
T
L
S
A
Site 20
S263
Q
P
E
Q
L
V
S
S
A
P
T
L
S
A
P
Site 21
T266
Q
L
V
S
S
A
P
T
L
S
A
P
E
K
E
Site 22
S268
V
S
S
A
P
T
L
S
A
P
E
K
E
S
T
Site 23
S274
L
S
A
P
E
K
E
S
T
G
T
S
G
P
L
Site 24
T275
S
A
P
E
K
E
S
T
G
T
S
G
P
L
Q
Site 25
T277
P
E
K
E
S
T
G
T
S
G
P
L
Q
R
P
Site 26
S278
E
K
E
S
T
G
T
S
G
P
L
Q
R
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation