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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NMNAT1
Full Name:
Nicotinamide mononucleotide adenylyltransferase 1
Alias:
Nicotinamide nucleotide adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NMN adenylyltransferase; NMN adenylyltransferase 1; NMNA1; NMNAT; PNAT1; PNAT-1
Type:
Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 2.7.7.1; Transferase
Mass (Da):
31932
Number AA:
279
UniProt ID:
Q9HAN9
International Prot ID:
IPI00009726
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0000309
PhosphoSite+
KinaseNET
Biological Process:
GO:0009435
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
L
F
E
L
A
K
D
Y
M
N
G
T
G
R
Y
Site 2
T38
A
K
D
Y
M
N
G
T
G
R
Y
T
V
V
K
Site 3
Y41
Y
M
N
G
T
G
R
Y
T
V
V
K
G
I
I
Site 4
Y55
I
S
P
V
G
D
A
Y
K
K
K
G
L
I
P
Site 5
Y64
K
K
G
L
I
P
A
Y
H
R
V
I
M
A
E
Site 6
T84
S
K
W
V
E
V
D
T
W
E
S
L
Q
K
E
Site 7
T95
L
Q
K
E
W
K
E
T
L
K
V
L
R
H
H
Site 8
S117
D
C
D
H
Q
Q
N
S
P
T
L
E
R
P
G
Site 9
T119
D
H
Q
Q
N
S
P
T
L
E
R
P
G
R
K
Site 10
T130
P
G
R
K
R
K
W
T
E
T
Q
D
S
S
Q
Site 11
T132
R
K
R
K
W
T
E
T
Q
D
S
S
Q
K
K
Site 12
S135
K
W
T
E
T
Q
D
S
S
Q
K
K
S
L
E
Site 13
S136
W
T
E
T
Q
D
S
S
Q
K
K
S
L
E
P
Site 14
S140
Q
D
S
S
Q
K
K
S
L
E
P
K
T
K
A
Site 15
T145
K
K
S
L
E
P
K
T
K
A
V
P
K
V
K
Site 16
S171
A
V
P
N
L
W
K
S
E
D
I
T
Q
I
V
Site 17
T175
L
W
K
S
E
D
I
T
Q
I
V
A
N
Y
G
Site 18
Y198
N
D
A
Q
K
F
I
Y
E
S
D
V
L
W
K
Site 19
S223
W
I
A
N
D
I
S
S
T
K
I
R
R
A
L
Site 20
S235
R
A
L
R
R
G
Q
S
I
R
Y
L
V
P
D
Site 21
Y238
R
R
G
Q
S
I
R
Y
L
V
P
D
L
V
Q
Site 22
Y247
V
P
D
L
V
Q
E
Y
I
E
K
H
N
L
Y
Site 23
Y254
Y
I
E
K
H
N
L
Y
S
S
E
S
E
D
R
Site 24
S256
E
K
H
N
L
Y
S
S
E
S
E
D
R
N
A
Site 25
S258
H
N
L
Y
S
S
E
S
E
D
R
N
A
G
V
Site 26
T274
L
A
P
L
Q
R
N
T
A
E
A
K
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation