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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PELI2
Full Name:
Protein pellino homolog 2
Alias:
Type:
Mass (Da):
46417
Number AA:
420
UniProt ID:
Q9HAT8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
P
N
K
E
P
V
K
Y
G
E
L
V
V
L
G
Site 2
S41
G
D
R
G
R
R
K
S
R
F
A
L
Y
K
R
Site 3
Y46
R
K
S
R
F
A
L
Y
K
R
P
K
A
N
G
Site 4
S57
K
A
N
G
V
K
P
S
T
V
H
V
I
S
T
Site 5
T58
A
N
G
V
K
P
S
T
V
H
V
I
S
T
P
Site 6
S63
P
S
T
V
H
V
I
S
T
P
Q
A
S
K
A
Site 7
T64
S
T
V
H
V
I
S
T
P
Q
A
S
K
A
I
Site 8
S68
V
I
S
T
P
Q
A
S
K
A
I
S
C
K
G
Site 9
S72
P
Q
A
S
K
A
I
S
C
K
G
Q
H
S
I
Site 10
S78
I
S
C
K
G
Q
H
S
I
S
Y
T
L
S
R
Site 11
S80
C
K
G
Q
H
S
I
S
Y
T
L
S
R
N
Q
Site 12
Y81
K
G
Q
H
S
I
S
Y
T
L
S
R
N
Q
T
Site 13
T82
G
Q
H
S
I
S
Y
T
L
S
R
N
Q
T
V
Site 14
S84
H
S
I
S
Y
T
L
S
R
N
Q
T
V
V
V
Site 15
T88
Y
T
L
S
R
N
Q
T
V
V
V
E
Y
T
H
Site 16
T108
M
F
Q
V
G
R
S
T
E
S
P
I
D
F
V
Site 17
S110
Q
V
G
R
S
T
E
S
P
I
D
F
V
V
T
Site 18
T119
I
D
F
V
V
T
D
T
I
S
G
S
Q
N
T
Site 19
S121
F
V
V
T
D
T
I
S
G
S
Q
N
T
D
E
Site 20
S123
V
T
D
T
I
S
G
S
Q
N
T
D
E
A
Q
Site 21
T132
N
T
D
E
A
Q
I
T
Q
S
T
I
S
R
F
Site 22
S134
D
E
A
Q
I
T
Q
S
T
I
S
R
F
A
C
Site 23
Y151
V
C
D
R
N
E
P
Y
T
A
R
I
F
A
A
Site 24
T152
C
D
R
N
E
P
Y
T
A
R
I
F
A
A
G
Site 25
S203
R
G
G
F
T
E
E
S
Q
P
G
V
W
R
E
Site 26
Y218
I
S
V
C
G
D
V
Y
T
L
R
E
T
R
S
Site 27
T219
S
V
C
G
D
V
Y
T
L
R
E
T
R
S
A
Site 28
T223
D
V
Y
T
L
R
E
T
R
S
A
Q
Q
R
G
Site 29
S225
Y
T
L
R
E
T
R
S
A
Q
Q
R
G
K
L
Site 30
S235
Q
R
G
K
L
V
E
S
E
T
N
V
L
Q
D
Site 31
T252
L
I
D
L
C
G
A
T
L
L
W
R
T
A
D
Site 32
T264
T
A
D
G
L
F
H
T
P
T
Q
K
H
I
E
Site 33
T266
D
G
L
F
H
T
P
T
Q
K
H
I
E
A
L
Site 34
T290
Q
C
P
V
G
L
N
T
L
A
F
P
S
I
N
Site 35
S295
L
N
T
L
A
F
P
S
I
N
R
K
E
V
V
Site 36
Y310
E
E
K
Q
P
W
A
Y
L
S
C
G
H
V
H
Site 37
T328
N
W
G
H
R
S
D
T
E
A
N
E
R
E
C
Site 38
T340
R
E
C
P
M
C
R
T
V
G
P
Y
V
P
L
Site 39
T363
Y
V
D
A
G
P
P
T
H
A
F
T
P
C
G
Site 40
T367
G
P
P
T
H
A
F
T
P
C
G
H
V
C
S
Site 41
Y380
C
S
E
K
S
A
K
Y
W
S
Q
I
P
L
P
Site 42
S382
E
K
S
A
K
Y
W
S
Q
I
P
L
P
H
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation