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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Fused
Full Name:
Serine/threonine-protein kinase 36
Alias:
EC 2.7.11.1; FU; Fused serine/threonine kinase; KIAA1278; Serine/threonine kinase 36, fused; STK36
Type:
EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Other group; ULK family
Mass (Da):
143995
Number AA:
1315
UniProt ID:
Q9NRP7
International Prot ID:
IPI00235407
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0009791
GO:0006468
GO:0051090
Phosida
TranscriptoNet
STRING
Kinexus Products
Serine/threonine-protein kinase 36 S159 phosphosite-specific antibody AB-PK643#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PK643#Serine/threonine-protein kinase 36 (V156-G162, human) pS159 phosphopeptide - Powder PE-04AMO99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AMO99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
L
E
M
I
G
E
G
S
F
G
R
V
Y
K
G
Site 2
Y19
E
G
S
F
G
R
V
Y
K
G
R
R
K
Y
S
Site 3
Y25
V
Y
K
G
R
R
K
Y
S
A
Q
V
V
A
L
Site 4
S26
Y
K
G
R
R
K
Y
S
A
Q
V
V
A
L
K
Site 5
S69
N
I
V
H
M
L
D
S
F
E
T
D
K
E
V
Site 6
S118
S
A
L
Y
Y
L
H
S
H
R
I
L
H
R
D
Site 7
Y166
S
I
K
G
T
P
L
Y
M
S
P
E
L
V
E
Site 8
S168
K
G
T
P
L
Y
M
S
P
E
L
V
E
E
R
Site 9
Y177
E
L
V
E
E
R
P
Y
D
H
T
A
D
L
W
Site 10
T180
E
E
R
P
Y
D
H
T
A
D
L
W
S
V
G
Site 11
S221
K
D
P
V
R
W
P
S
T
I
S
P
C
F
K
Site 12
T222
D
P
V
R
W
P
S
T
I
S
P
C
F
K
N
Site 13
T236
N
F
L
Q
G
L
L
T
K
D
P
R
Q
R
L
Site 14
S244
K
D
P
R
Q
R
L
S
W
P
D
L
L
Y
H
Site 15
T271
P
A
G
P
D
L
G
T
P
F
T
S
R
L
P
Site 16
T274
P
D
L
G
T
P
F
T
S
R
L
P
P
E
L
Site 17
T303
G
N
Q
S
R
I
L
T
Q
A
Y
K
R
M
A
Site 18
Y306
S
R
I
L
T
Q
A
Y
K
R
M
A
E
E
A
Site 19
T331
A
L
E
Q
E
D
K
T
S
K
V
A
P
G
T
Site 20
S332
L
E
Q
E
D
K
T
S
K
V
A
P
G
T
A
Site 21
T347
P
L
P
R
L
G
A
T
P
Q
E
S
S
L
L
Site 22
S364
I
L
A
S
E
L
K
S
S
W
A
K
S
G
T
Site 23
S365
L
A
S
E
L
K
S
S
W
A
K
S
G
T
G
Site 24
S369
L
K
S
S
W
A
K
S
G
T
G
E
V
P
S
Site 25
S376
S
G
T
G
E
V
P
S
A
P
R
E
N
R
T
Site 26
T384
A
P
R
E
N
R
T
T
P
D
C
E
R
A
F
Site 27
T404
E
V
L
G
Q
R
S
T
D
V
V
D
L
E
N
Site 28
S416
L
E
N
E
E
P
D
S
D
N
E
W
Q
H
L
Site 29
T426
E
W
Q
H
L
L
E
T
T
E
P
V
P
I
Q
Site 30
S452
D
F
C
Q
R
I
Q
S
Q
L
H
E
A
G
G
Site 31
S512
L
L
S
L
L
R
H
S
Q
E
S
N
S
L
Q
Site 32
S515
L
L
R
H
S
Q
E
S
N
S
L
Q
Q
Q
S
Site 33
S517
R
H
S
Q
E
S
N
S
L
Q
Q
Q
S
W
Y
Site 34
S548
C
T
F
N
L
E
R
S
Q
T
S
D
S
L
Q
Site 35
T550
F
N
L
E
R
S
Q
T
S
D
S
L
Q
V
F
Site 36
S553
E
R
S
Q
T
S
D
S
L
Q
V
F
Q
E
A
Site 37
T581
Q
P
D
D
S
E
Q
T
L
R
R
D
S
L
M
Site 38
S586
E
Q
T
L
R
R
D
S
L
M
C
F
T
V
L
Site 39
S601
C
E
A
M
D
G
N
S
R
A
I
S
K
A
F
Site 40
S605
D
G
N
S
R
A
I
S
K
A
F
Y
S
S
L
Site 41
Y609
R
A
I
S
K
A
F
Y
S
S
L
L
T
T
Q
Site 42
T636
V
P
Q
L
P
V
H
T
P
Q
G
A
P
Q
V
Site 43
S644
P
Q
G
A
P
Q
V
S
Q
P
L
R
E
Q
S
Site 44
S651
S
Q
P
L
R
E
Q
S
E
D
I
P
G
A
I
Site 45
T691
W
H
L
A
N
Q
L
T
E
D
S
S
Q
L
R
Site 46
S695
N
Q
L
T
E
D
S
S
Q
L
R
P
S
L
I
Site 47
S700
D
S
S
Q
L
R
P
S
L
I
S
G
L
Q
H
Site 48
T816
Q
L
G
Q
Q
G
V
T
F
D
L
Q
P
M
E
Site 49
S867
L
T
E
Q
G
K
A
S
L
I
R
D
M
S
S
Site 50
S873
A
S
L
I
R
D
M
S
S
S
E
M
W
T
V
Site 51
S896
L
R
L
P
E
E
A
S
A
Q
E
G
E
L
S
Site 52
S903
S
A
Q
E
G
E
L
S
L
S
S
P
P
S
P
Site 53
S905
Q
E
G
E
L
S
L
S
S
P
P
S
P
E
P
Site 54
S906
E
G
E
L
S
L
S
S
P
P
S
P
E
P
D
Site 55
S909
L
S
L
S
S
P
P
S
P
E
P
D
W
T
L
Site 56
T915
P
S
P
E
P
D
W
T
L
I
S
P
Q
G
M
Site 57
S918
E
P
D
W
T
L
I
S
P
Q
G
M
A
A
L
Site 58
S942
Q
E
P
Q
L
C
L
S
C
L
S
Q
H
G
S
Site 59
S962
L
K
H
L
L
C
P
S
F
L
N
Q
L
R
Q
Site 60
T1054
S
L
N
Q
F
V
N
T
V
S
A
S
P
R
T
Site 61
S1095
T
A
R
V
L
S
P
S
H
L
S
F
I
Q
E
Site 62
S1110
L
L
A
G
S
D
E
S
Y
R
P
L
R
S
L
Site 63
Y1111
L
A
G
S
D
E
S
Y
R
P
L
R
S
L
L
Site 64
S1116
E
S
Y
R
P
L
R
S
L
L
G
H
P
E
N
Site 65
S1124
L
L
G
H
P
E
N
S
V
R
A
H
T
Y
R
Site 66
T1129
E
N
S
V
R
A
H
T
Y
R
L
L
G
H
L
Site 67
Y1181
F
A
V
G
N
A
A
Y
Q
A
G
P
L
G
P
Site 68
S1214
G
I
R
R
N
V
A
S
A
L
G
N
L
G
P
Site 69
S1283
S
E
K
L
S
L
L
S
L
G
N
Q
S
L
P
Site 70
S1288
L
L
S
L
G
N
Q
S
L
P
H
S
S
P
R
Site 71
S1292
G
N
Q
S
L
P
H
S
S
P
R
P
A
S
A
Site 72
S1293
N
Q
S
L
P
H
S
S
P
R
P
A
S
A
K
Site 73
S1298
H
S
S
P
R
P
A
S
A
K
H
C
R
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation