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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAG
Full Name:
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1
Alias:
CBP; CSK binding protein; Csk-binding protein; PAG1; Phosphoprotein associated with GEMs; Phosphoprotein associated with glycosphingolipid microdomains 1
Type:
Adapter/scaffold protein
Mass (Da):
46981
Number AA:
432
UniProt ID:
Q9NWQ8
International Prot ID:
IPI00020464
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0045121
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0042169
GO:0005070
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
GO:0007242
GO:0050863
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S38
T
F
L
I
F
L
C
S
S
C
D
R
E
K
K
Site 2
S39
F
L
I
F
L
C
S
S
C
D
R
E
K
K
P
Site 3
S50
E
K
K
P
R
Q
H
S
G
D
H
E
N
L
M
Site 4
S61
E
N
L
M
N
V
P
S
D
K
E
M
F
S
R
Site 5
S67
P
S
D
K
E
M
F
S
R
S
V
T
S
L
A
Site 6
S69
D
K
E
M
F
S
R
S
V
T
S
L
A
T
D
Site 7
T71
E
M
F
S
R
S
V
T
S
L
A
T
D
A
P
Site 8
S72
M
F
S
R
S
V
T
S
L
A
T
D
A
P
A
Site 9
T75
R
S
V
T
S
L
A
T
D
A
P
A
S
S
E
Site 10
S80
L
A
T
D
A
P
A
S
S
E
Q
N
G
A
L
Site 11
T88
S
E
Q
N
G
A
L
T
N
G
D
I
L
S
E
Site 12
S94
L
T
N
G
D
I
L
S
E
D
S
T
L
T
C
Site 13
S97
G
D
I
L
S
E
D
S
T
L
T
C
M
Q
H
Site 14
T98
D
I
L
S
E
D
S
T
L
T
C
M
Q
H
Y
Site 15
Y105
T
L
T
C
M
Q
H
Y
E
E
V
Q
T
S
A
Site 16
T110
Q
H
Y
E
E
V
Q
T
S
A
S
D
L
L
D
Site 17
S111
H
Y
E
E
V
Q
T
S
A
S
D
L
L
D
S
Site 18
S113
E
E
V
Q
T
S
A
S
D
L
L
D
S
Q
D
Site 19
S118
S
A
S
D
L
L
D
S
Q
D
S
T
G
K
P
Site 20
T122
L
L
D
S
Q
D
S
T
G
K
P
K
C
H
Q
Site 21
S130
G
K
P
K
C
H
Q
S
R
E
L
P
R
I
P
Site 22
T144
P
P
E
S
A
V
D
T
M
L
T
A
R
S
V
Site 23
T147
S
A
V
D
T
M
L
T
A
R
S
V
D
G
D
Site 24
S150
D
T
M
L
T
A
R
S
V
D
G
D
Q
G
L
Site 25
Y163
G
L
G
M
E
G
P
Y
E
V
L
K
D
S
S
Site 26
S169
P
Y
E
V
L
K
D
S
S
S
Q
E
N
M
V
Site 27
S171
E
V
L
K
D
S
S
S
Q
E
N
M
V
E
D
Site 28
Y181
N
M
V
E
D
C
L
Y
E
T
V
K
E
I
K
Site 29
T183
V
E
D
C
L
Y
E
T
V
K
E
I
K
E
V
Site 30
S201
A
H
L
E
K
G
H
S
G
K
A
K
S
T
S
Site 31
S206
G
H
S
G
K
A
K
S
T
S
A
S
K
E
L
Site 32
S208
S
G
K
A
K
S
T
S
A
S
K
E
L
P
G
Site 33
S210
K
A
K
S
T
S
A
S
K
E
L
P
G
P
Q
Site 34
Y227
G
K
A
E
F
A
E
Y
A
S
V
D
R
N
K
Site 35
S229
A
E
F
A
E
Y
A
S
V
D
R
N
K
K
C
Site 36
S239
R
N
K
K
C
R
Q
S
V
N
V
E
S
I
L
Site 37
S244
R
Q
S
V
N
V
E
S
I
L
G
N
S
C
D
Site 38
S249
V
E
S
I
L
G
N
S
C
D
P
E
E
E
A
Site 39
S282
E
G
G
E
A
E
E
S
A
T
D
T
T
S
E
Site 40
T284
G
E
A
E
E
S
A
T
D
T
T
S
E
T
N
Site 41
T286
A
E
E
S
A
T
D
T
T
S
E
T
N
K
R
Site 42
S288
E
S
A
T
D
T
T
S
E
T
N
K
R
F
S
Site 43
T290
A
T
D
T
T
S
E
T
N
K
R
F
S
S
L
Site 44
S295
S
E
T
N
K
R
F
S
S
L
S
Y
K
S
R
Site 45
S296
E
T
N
K
R
F
S
S
L
S
Y
K
S
R
E
Site 46
S298
N
K
R
F
S
S
L
S
Y
K
S
R
E
E
D
Site 47
Y299
K
R
F
S
S
L
S
Y
K
S
R
E
E
D
P
Site 48
S301
F
S
S
L
S
Y
K
S
R
E
E
D
P
T
L
Site 49
T307
K
S
R
E
E
D
P
T
L
T
E
E
E
I
S
Site 50
T309
R
E
E
D
P
T
L
T
E
E
E
I
S
A
M
Site 51
S314
T
L
T
E
E
E
I
S
A
M
Y
S
S
V
N
Site 52
Y317
E
E
E
I
S
A
M
Y
S
S
V
N
K
P
G
Site 53
S318
E
E
I
S
A
M
Y
S
S
V
N
K
P
G
Q
Site 54
S319
E
I
S
A
M
Y
S
S
V
N
K
P
G
Q
L
Site 55
S330
P
G
Q
L
V
N
K
S
G
Q
S
L
T
V
P
Site 56
S333
L
V
N
K
S
G
Q
S
L
T
V
P
E
S
T
Site 57
T335
N
K
S
G
Q
S
L
T
V
P
E
S
T
Y
T
Site 58
S339
Q
S
L
T
V
P
E
S
T
Y
T
S
I
Q
G
Site 59
T340
S
L
T
V
P
E
S
T
Y
T
S
I
Q
G
D
Site 60
Y341
L
T
V
P
E
S
T
Y
T
S
I
Q
G
D
P
Site 61
T342
T
V
P
E
S
T
Y
T
S
I
Q
G
D
P
Q
Site 62
S343
V
P
E
S
T
Y
T
S
I
Q
G
D
P
Q
R
Site 63
S351
I
Q
G
D
P
Q
R
S
P
S
S
C
N
D
L
Site 64
S353
G
D
P
Q
R
S
P
S
S
C
N
D
L
Y
A
Site 65
S354
D
P
Q
R
S
P
S
S
C
N
D
L
Y
A
T
Site 66
Y359
P
S
S
C
N
D
L
Y
A
T
V
K
D
F
E
Site 67
T361
S
C
N
D
L
Y
A
T
V
K
D
F
E
K
T
Site 68
T368
T
V
K
D
F
E
K
T
P
N
S
T
L
P
P
Site 69
S371
D
F
E
K
T
P
N
S
T
L
P
P
A
G
R
Site 70
T372
F
E
K
T
P
N
S
T
L
P
P
A
G
R
P
Site 71
S380
L
P
P
A
G
R
P
S
E
E
P
E
P
D
Y
Site 72
Y387
S
E
E
P
E
P
D
Y
E
A
I
Q
T
L
N
Site 73
T392
P
D
Y
E
A
I
Q
T
L
N
R
E
E
E
K
Site 74
T401
N
R
E
E
E
K
A
T
L
G
T
N
G
H
H
Site 75
Y417
L
V
P
K
E
N
D
Y
E
S
I
S
D
L
Q
Site 76
S419
P
K
E
N
D
Y
E
S
I
S
D
L
Q
Q
G
Site 77
S421
E
N
D
Y
E
S
I
S
D
L
Q
Q
G
R
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation