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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WWOX
Full Name:
WW domain-containing oxidoreductase
Alias:
Aberrant WW domain-containing oxidoreductase; EC 1.1.1.-; FOR; WOX1
Type:
Apoptosis protein; Enzyme - Oxidoreductase; Cytoplasm, nucleus, mitochondrio, Golgi apparatus protein
Mass (Da):
46677
Number AA:
414
UniProt ID:
Q9NZC7
International Prot ID:
IPI00299802
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005739
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0050662
GO:0016491
GO:0046983
PhosphoSite+
KinaseNET
Biological Process:
GO:0030178
GO:0055114
GO:0008202
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
R
Y
A
G
L
D
D
T
D
S
E
D
E
L
P
Site 2
S14
A
G
L
D
D
T
D
S
E
D
E
L
P
P
G
Site 3
Y33
T
T
K
D
G
W
V
Y
Y
A
N
H
T
E
E
Site 4
Y34
T
K
D
G
W
V
Y
Y
A
N
H
T
E
E
K
Site 5
T49
T
Q
W
E
H
P
K
T
G
K
R
K
R
V
A
Site 6
Y61
R
V
A
G
D
L
P
Y
G
W
E
Q
E
T
D
Site 7
T84
D
H
I
N
K
R
T
T
Y
L
D
P
R
L
A
Site 8
Y85
H
I
N
K
R
T
T
Y
L
D
P
R
L
A
F
Site 9
T93
L
D
P
R
L
A
F
T
V
D
D
N
P
T
K
Site 10
Y107
K
P
T
T
R
Q
R
Y
D
G
S
T
T
A
M
Site 11
S110
T
R
Q
R
Y
D
G
S
T
T
A
M
E
I
L
Site 12
T111
R
Q
R
Y
D
G
S
T
T
A
M
E
I
L
Q
Site 13
S162
C
R
N
M
A
R
A
S
E
A
V
S
R
I
L
Site 14
S166
A
R
A
S
E
A
V
S
R
I
L
E
E
W
H
Site 15
T228
T
K
D
G
L
E
T
T
F
Q
V
N
H
L
G
Site 16
S259
P
A
R
V
I
V
V
S
S
E
S
H
R
F
T
Site 17
T266
S
S
E
S
H
R
F
T
D
I
N
D
S
L
G
Site 18
S271
R
F
T
D
I
N
D
S
L
G
K
L
D
F
S
Site 19
S278
S
L
G
K
L
D
F
S
R
L
S
P
T
K
N
Site 20
S281
K
L
D
F
S
R
L
S
P
T
K
N
D
Y
W
Site 21
Y287
L
S
P
T
K
N
D
Y
W
A
M
L
A
Y
N
Site 22
Y293
D
Y
W
A
M
L
A
Y
N
R
S
K
L
C
N
Site 23
S312
N
E
L
H
R
R
L
S
P
R
G
V
T
S
N
Site 24
T317
R
L
S
P
R
G
V
T
S
N
A
V
H
P
G
Site 25
S318
L
S
P
R
G
V
T
S
N
A
V
H
P
G
N
Site 26
T349
F
T
L
A
R
P
F
T
K
S
M
Q
Q
G
A
Site 27
S351
L
A
R
P
F
T
K
S
M
Q
Q
G
A
A
T
Site 28
S385
N
C
C
R
C
M
P
S
P
E
A
Q
S
E
E
Site 29
T396
Q
S
E
E
T
A
R
T
L
W
A
L
S
E
R
Site 30
S401
A
R
T
L
W
A
L
S
E
R
L
I
Q
E
R
Site 31
S411
L
I
Q
E
R
L
G
S
Q
S
G
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation