KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DRAK1
Full Name:
Death-associated protein kinase-related apoptosis inducing protein kinase 1
Alias:
DAP kinase-related apoptosis-inducing protein kinase 1; Death-associated protein kinase-related 1; EC 2.7.11.1; Kinase DRAK1; Serine,threonine kinase 17A; Serine/threonine kinase 17A; St17a; ST17A; Stk17a; STK17A
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1;
CAMK
group; DAPK family
Mass (Da):
46559
Number AA:
414
UniProt ID:
Q9UEE5
International Prot ID:
IPI00646659
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006917
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
I
P
L
E
K
P
G
S
G
G
S
S
P
G
A
Site 2
S12
E
K
P
G
S
G
G
S
S
P
G
A
T
S
G
Site 3
S13
K
P
G
S
G
G
S
S
P
G
A
T
S
G
S
Site 4
T17
G
G
S
S
P
G
A
T
S
G
S
G
R
A
G
Site 5
S18
G
S
S
P
G
A
T
S
G
S
G
R
A
G
R
Site 6
S20
S
P
G
A
T
S
G
S
G
R
A
G
R
G
L
Site 7
S28
G
R
A
G
R
G
L
S
G
P
C
R
P
P
P
Site 8
T52
E
I
R
A
V
V
R
T
E
P
F
Q
D
G
Y
Site 9
Y59
T
E
P
F
Q
D
G
Y
S
L
C
P
G
R
E
Site 10
S60
E
P
F
Q
D
G
Y
S
L
C
P
G
R
E
L
Site 11
T195
K
P
Q
N
I
L
L
T
S
E
S
P
L
G
D
Site 12
S196
P
Q
N
I
L
L
T
S
E
S
P
L
G
D
I
Site 13
S211
K
I
V
D
F
G
L
S
R
I
L
K
N
S
E
Site 14
S217
L
S
R
I
L
K
N
S
E
E
L
R
E
I
M
Site 15
T226
E
L
R
E
I
M
G
T
P
E
Y
V
A
P
E
Site 16
T271
L
G
N
D
K
Q
E
T
F
L
N
I
S
Q
M
Site 17
S276
Q
E
T
F
L
N
I
S
Q
M
N
L
S
Y
S
Site 18
S281
N
I
S
Q
M
N
L
S
Y
S
E
E
E
F
D
Site 19
S283
S
Q
M
N
L
S
Y
S
E
E
E
F
D
V
L
Site 20
S291
E
E
E
F
D
V
L
S
E
S
A
V
D
F
I
Site 21
T311
K
K
P
E
D
R
A
T
A
E
E
C
L
K
H
Site 22
T322
C
L
K
H
P
W
L
T
Q
S
S
I
Q
E
P
Site 23
S324
K
H
P
W
L
T
Q
S
S
I
Q
E
P
S
F
Site 24
S330
Q
S
S
I
Q
E
P
S
F
R
M
E
K
A
L
Site 25
S348
N
A
L
Q
E
G
H
S
V
P
E
I
N
S
D
Site 26
S354
H
S
V
P
E
I
N
S
D
T
D
K
S
E
T
Site 27
T356
V
P
E
I
N
S
D
T
D
K
S
E
T
E
E
Site 28
S359
I
N
S
D
T
D
K
S
E
T
E
E
S
I
V
Site 29
S364
D
K
S
E
T
E
E
S
I
V
T
E
E
L
I
Site 30
S384
T
L
G
Q
C
R
Q
S
E
K
E
K
M
E
Q
Site 31
S395
K
M
E
Q
K
A
I
S
K
R
F
K
F
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation