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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC24A2
Full Name:
Sodium/potassium/calcium exchanger 2 precursor
Alias:
Na(+)/K(+)/Ca(2+)-exchange protein 2; NCKX2; Retinal cone Na-Ca+K exchanger; Solute carrier family 24 (sodium/potassium/calcium exchanger) member 2; Solute carrier family 24 member 2
Type:
Transport protein, facilitator
Mass (Da):
73664
Number AA:
661
UniProt ID:
Q9UI40
International Prot ID:
IPI00006444
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0015297
GO:0005509
GO:0030955
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0006813
GO:0006814
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
L
Q
Q
S
T
T
I
T
S
L
E
K
W
C
L
Site 2
S20
E
K
W
C
L
D
E
S
L
S
G
C
R
R
H
Site 3
Y28
L
S
G
C
R
R
H
Y
S
V
K
K
K
L
K
Site 4
S29
S
G
C
R
R
H
Y
S
V
K
K
K
L
K
L
Site 5
S57
S
T
V
S
F
S
I
S
A
F
S
E
T
D
T
Site 6
S60
S
F
S
I
S
A
F
S
E
T
D
T
Q
S
T
Site 7
T62
S
I
S
A
F
S
E
T
D
T
Q
S
T
G
E
Site 8
T64
S
A
F
S
E
T
D
T
Q
S
T
G
E
A
S
Site 9
S71
T
Q
S
T
G
E
A
S
V
V
S
G
P
R
V
Site 10
S74
T
G
E
A
S
V
V
S
G
P
R
V
A
Q
G
Site 11
Y82
G
P
R
V
A
Q
G
Y
H
Q
R
T
L
L
D
Site 12
Y97
L
N
D
K
I
L
D
Y
T
P
Q
P
P
L
S
Site 13
T98
N
D
K
I
L
D
Y
T
P
Q
P
P
L
S
K
Site 14
S104
Y
T
P
Q
P
P
L
S
K
E
G
E
S
E
N
Site 15
S112
K
E
G
E
S
E
N
S
T
D
H
A
Q
G
D
Site 16
T113
E
G
E
S
E
N
S
T
D
H
A
Q
G
D
Y
Site 17
Y120
T
D
H
A
Q
G
D
Y
P
K
D
I
F
S
L
Site 18
S126
D
Y
P
K
D
I
F
S
L
E
E
R
R
K
G
Site 19
T165
V
P
S
L
T
V
I
T
E
K
L
G
I
S
D
Site 20
T321
A
R
D
K
D
E
P
T
L
P
A
K
P
R
L
Site 21
S333
P
R
L
Q
R
G
G
S
S
A
S
L
H
N
S
Site 22
S334
R
L
Q
R
G
G
S
S
A
S
L
H
N
S
L
Site 23
S336
Q
R
G
G
S
S
A
S
L
H
N
S
L
M
R
Site 24
S340
S
S
A
S
L
H
N
S
L
M
R
N
S
I
F
Site 25
S363
P
L
A
E
E
L
G
S
Y
G
K
L
K
Y
Y
Site 26
Y364
L
A
E
E
L
G
S
Y
G
K
L
K
Y
Y
D
Site 27
Y369
G
S
Y
G
K
L
K
Y
Y
D
T
M
T
E
E
Site 28
Y370
S
Y
G
K
L
K
Y
Y
D
T
M
T
E
E
G
Site 29
T372
G
K
L
K
Y
Y
D
T
M
T
E
E
G
R
F
Site 30
T374
L
K
Y
Y
D
T
M
T
E
E
G
R
F
R
E
Site 31
S417
E
K
I
E
L
P
N
S
T
S
T
D
V
E
M
Site 32
S419
I
E
L
P
N
S
T
S
T
D
V
E
M
T
P
Site 33
T425
T
S
T
D
V
E
M
T
P
S
S
D
A
S
E
Site 34
S427
T
D
V
E
M
T
P
S
S
D
A
S
E
P
V
Site 35
S428
D
V
E
M
T
P
S
S
D
A
S
E
P
V
Q
Site 36
S431
M
T
P
S
S
D
A
S
E
P
V
Q
N
G
N
Site 37
S440
P
V
Q
N
G
N
L
S
H
N
I
E
G
A
E
Site 38
S460
E
E
E
D
Q
P
L
S
L
A
W
P
S
E
T
Site 39
T467
S
L
A
W
P
S
E
T
R
K
Q
V
T
F
L
Site 40
S494
L
P
D
V
R
K
P
S
S
R
K
F
F
P
I
Site 41
S495
P
D
V
R
K
P
S
S
R
K
F
F
P
I
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation